HsaINT0044297 @ hg19
Intron Retention
Gene
ENSG00000130649 | CYP2E1
Description
cytochrome P450, family 2, subfamily E, polypeptide 1 [Source:HGNC Symbol;Acc:2631]
Coordinates
chr10:135345628-135346372:+
Coord C1 exon
chr10:135345628-135345788
Coord A exon
chr10:135345789-135346195
Coord C2 exon
chr10:135346196-135346372
Length
407 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAAG
5' ss Score
6.66
3' ss Seq
ATATTTTTTTCCCTCTCTAGCTT
3' ss Score
9.86
Exon sequences
Seq C1 exon
GCCAGCCTTTCGACCCCACCTTCCTCATCGGCTGCGCGCCCTGCAACGTCATAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTGATGTATTTGTTTAATGAGAACTTCCACCTACTCAGCACTCCCTGGCTCCAG
Seq A exon
GTGAAGCCACTTTCCTCTTTCATCAGTCATCAACTGTAGAGTTTACGTTAGAAAAAGAAGGAAAATTTGGGTTATATGTGATAGACAGGACTGCAAAAGCCAAACAACATAGCTTCGAGGGGTGTTTGATTAGACAGCCCAAATATTCCTCCCAGAGACATCTCTGGGGCCCCACGCACCCCCTTTCCTAACGTCAGGATGTGTATCGACCTGTGTGTGCACATTTGCCATGCAGAGTTTGCACTGCTGAGGAGAATGGTGCCCAAGAAGGACACTGTTGACCCAAAATATTCCAAATAAACAATGATTACAGCCACAAATTCAGGTTTGGAGAAAGTTGTTGGTCCAACACACACAATTATGTTGCATCCAGAAAAAAGTAGTAAAATATTTTTTTCCCTCTCTAG
Seq C2 exon
CTTTACAATAATTTTCCCAGCTTTCTACACTACTTGCCTGGAAGCCACAGAAAAGTCATAAAAAATGTGGCTGAAGTAAAAGAGTATGTGTCTGAAAGGGTGAAGGAGCACCATCAATCTCTGGACCCCAACTGTCCCCGGGACCTCACCGACTGCCTGCTCGTGGAAATGGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130649-CYP2E1:NM_000773:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.148 A=NA C2=0.017
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(11.6=100)
A:
NA
C2:
PF0006717=p450=FE(12.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCTTTCGACCCCACCTTC
R:
TTCTCCATTTCCACGAGCAGG
Band lengths:
334-741
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)