HsaINT0044554 @ hg19
Intron Retention
Gene
ENSG00000186377 | CYP4X1
Description
cytochrome P450, family 4, subfamily X, polypeptide 1 [Source:HGNC Symbol;Acc:20244]
Coordinates
chr1:47512139-47514301:+
Coord C1 exon
chr1:47512139-47512272
Coord A exon
chr1:47512273-47514236
Coord C2 exon
chr1:47514237-47514301
Length
1964 bp
Sequences
Splice sites
5' ss Seq
CAGGTCTTT
5' ss Score
2.36
3' ss Seq
TTATTTCCCTCCTTTCTTAGGGA
3' ss Score
11.24
Exon sequences
Seq C1 exon
GGACCAGCTGGGTGAGATGTCGTACACCACAATGTGCATCAAGGAGACGTGCCGATTGATTCCTGCAGTCCCGTCCATTTCCAGAGATCTCAGCAAGCCACTTACCTTCCCAGATGGATGCACATTGCCTGCAG
Seq A exon
GTCTTTACATTCTTTTCCTAAGCAGTTCTTAGAGGCTATGGGATCCTGGAGACCACAGTGACAAAGATTAGTGAGTCTCTTAGCACTTGGAGAAGTCAAAAGATAATGCTAACATGTGACTTAGGTTTTATCACCTATGAGGAGCTCAGAGGATAATGCTTTGGTCAGACATGAATTTCAATGACTTTCCCAAAGGCACATAGCCAGTTGCAGCAAAGCTAAGCCCAGAATCCATGTCTCTGGAATCCCAGCCCAGGGTCTCTTCCATTGTGGGACATCATTTCTAAGATAATCTTTGTTTGGCTGAGTTTGAGACCGAGCTGAAACTTCATGGAAAATAGCACCAGCATCTTTATCTGAAAGACCAAGGGGGATCTTTGGCCTCATCATCATAATATCACCCTTATAAATATACAACATTTAATAGTTAATATAGAGCCTTCAGACCCATTATCTCATTTTTCCCCTTGGAATCCAATGTTAACAGACGCTTATACAATGATTTACAGTTCACTGAACACTTTTAAGTACTTTCAATGTGGCCCAAAATCCAGAGGCAGCCCCAATGTGTAGATGACATTAACTGATGTGAGCAGAGCTAGAACTTGTGCGGAGACCCTGAGTCTGGAGCCTAGAGTTCTTCGGAACAACACAGGTTTCTGAGCAGGGCTTATAGGAAGCAGAGGGGTCATGTGAGACATATTATCTGATTCAATGTTCTATTAATTCATGTCTTAGGAAGCAAGCCAACAGGATTGCTTCTGGCAAACACCTACAGCCTGTTACTGTAACTTTGCTGACAGACCCAGAATTAATTTCTGGAAGCTAGAATTATTTCTGGAAACCAAATAACCCTCACATTCTCTCTCCTTTGTTTTGTACTCTGTTTCTCCCCAAACCACATGGATATTTGCCAAAATTCTCCACTTTCCATATGTGAATAGCACCAATGGAAATTTGTCATGGGATCTGCATGACAGAATCACAGTTCTGTGTGTGTGTGTGTGCGTTTTCCTCTCAAGACAGAGTCTTGCTATGTAGCCCAGGCTGGAGTACAGTGGCGTAATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTTAAGCAGTTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCACACCACGCCTGGCAAATTTTTGTATTTTTATTAGAGATGGGGTTTCACCATGTTGGCCAGGCTAGTCTCAAGCTCCTGATCTCGAGACCAGCCCTCCTCAGCCTCCCAAAGCGCTGGGACTACAGCCATGAGCCACTGCACCCAGCCAGTTCTGTGCTTTTATACCTAAATTGTCTCCAGGAGTGCTTAATAGTCCATTAATAGGTATTTAGGCCAGGCACAGTGGCTGACGCATATAATCCCAATATTTTGTGACACCAAGGTGGGAAGACTGCTTGAAGTTAGGAGTCTGAGACTAGCCTGGGCAACATAGGGAGACCCTGTCTTTACAAAAAAAAAAAAAGAGAGAGATAGCCAGGCATGGTGTTGCATGCTTGTATTCCTGCCTACTTGGGGGACTGAGGCAGGAGGATCACTTGAGCTCAGAAGTTCAAGGTTACCGTGAGCAATGTTCACGCCACTGCTCTCCAGCCTGATTGACAGGCCAGACCCTGACTCTAAACAAAAACAAAAAACAAATATTTAAGTAATTTCCAAACATAGCAGAAAATATAAGCATGGTTTATCACTTTGATATGACACCAACAGCTACTTAAGATAGAATCATGAATTCAGTAAATTGTTGTGTGGAAAGCTAAGGTGCCAACCCAAGCCGCATCTTCTTAGGTGCTCCTCACTGGTGTCATCAGCTACAGCAGGCAGAGCATTGCCAGGAGCTAGCTCTTCCCTTCAAGAACAAAAGTCTTGTTTAAGAGCACAGTAGCCCACAACTTGCTCTTTCTCCTGCAGTCTCTTTTATTTCCCTCCTTTCTTAG
Seq C2 exon
GGATCACCGTGGTTCTTAGTATTTGGGGTCTTCACCACAACCCTGCTGTCTGGAAAAACCCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186377-CYP4X1:NM_178033:9
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(10.0=100)
A:
NA
C2:
PF0006717=p450=FE(4.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTGGGTGAGATGTCGTACA
R:
TGGGTTTTTCCAGACAGCAGG
Band lengths:
191-2155
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)