HsaINT0048146 @ hg19
Intron Retention
Gene
ENSG00000066084 | DIP2B
Description
DIP2 disco-interacting protein 2 homolog B (Drosophila) [Source:HGNC Symbol;Acc:29284]
Coordinates
chr12:51069112-51072659:+
Coord C1 exon
chr12:51069112-51069231
Coord A exon
chr12:51069232-51072461
Coord C2 exon
chr12:51072462-51072659
Length
3230 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGTA
5' ss Score
5.69
3' ss Seq
TTGGGATTTTCCTGGTACAGTAC
3' ss Score
3.09
Exon sequences
Seq C1 exon
GTGTTCCTGTCAGTAGCAGAGTATCTACAAAAATCCAGCAGCTTCTGAACACTCTGAAACGACCCAAAAGGCCTCCCTTAAAGGAATTTTTTGTGGATGACTCTGAAGAAATTGTGGAAG
Seq A exon
GTAGTAGTAAAAATACCAAAAACATATATTCATTAAATAAATATATCTTAAGCAGTTACTATGTGTTAGGTACTGTAGGGTTAAAGAATGAACAAGACACAGTTCTTGGTTCAAAGAGTTCATCATTTTCTGCTCTTTTTTCCCTAATGATTATCTGTATTTTAGATCTTAGATGAAAATTAAGGAGGGAAGGAAGAAGAGGGAAGAAAGGCAAAGAGATCACCATGGAGCATAGAACTGTCTTTGGAAATAAACTCTTTGAAATTAGGAACTATCCCAAATACATGATTTTACGAGTTATTTATATTTGGCATTTTCTCGGATGTGGATATCAAATTCAGCCTCAAAAGTTTGCCTACTCTGTTTTCATATAATGTAATCCTTTTATGAATCAACCAATCAATACATATTTCTGCTTTCTACAAGGCAGCGTGTTAGATGGTGAAAAGGTTCAAAGATTTATAAAAATACAGTTATTTCCTTCATGTTGTTTACAATTTAGACGGGTGCTAAAATATATCCATGTGAATACTTAGTTTAAGTATTAAGTATCTATCAGCCAATATAGGCACTTCTGAGAAGGGAAGAAATCAGTTCCTTCTGGGTTAGGAAAGGCTTCACAGAGGAAGTGTAACAGTGATTTATTCATTCAATAATTTTTAAATTATGGATAAAACCATATATCTAGGATTTAATAGGGAAGGGGAATGAGTGTGAGTATGGATAAAATGAGAATGGCCATTTGATAATTATAGAGTGATGACGATAGATCTAGACAAATAGATCTACCTAAGAAAAGCTTTTGTTGAAAGAGCTAAGCGTTGGTAGCTTTGTAGTCTGTTTTTATGTCCTGAGACTAATAGTAATAGGTTTTGATCACATCAGCTTGTTAATAGAATTAGGTACATTGGTAGACTAGATCTGGTCTTAGCCCAATTTATACCGCAGAAAGCAACCTGACATATGAGGTTAAGATGAGTATCTGTTTTTTTAGGAATCACTAAACTCATTGAATGGTGGACGTCTTTCATGATGTACTGATGTTCAAGATGTCCACGCCAGCAATAGCCTTTCCAGTGTTTTTAGCATTGGGTATTGACCAGGCACATGAAGGTCACGGTTTTTAACAGGAATCTTACCTGAAAAAATTGCATTGGCAGAATAGAACTAACAACTTTCCATTAATTACTAATATAAATAGGCAATAGTTGCTTGTTTGAGTAATTGTCACCTTTGGAAAAGAAAAATACCAGTAGGTCTTTGGAAATCTGAAAGAGCATGCCCCAGAATCTGCATTGAAGCCTAATGGATAATGGCGATAATGTCAGCTTTCATGGCAGGAAACAATGCCTACTATATACATAGTCTGTCCAAACAAATACAATACTTATTTAGAAACACCCATGTTTATTTTTTTTAGTTAATCTGGTGGTTTAGCGTCTGGGAATGTACAAAGCAGAAGGGCAGTTGAAACATTTATTATTTACCCTAAGGCAGCAAATTGGGGAGTGAAACTATTTCATGAATGTTACGTTAGTAGAAAAATGAATCAAGGCATTTTAAGTACAATCCCCAGATTTGTCATTGAGCTATAAAACATTTATTTCATATTTCATTTGCCCATCTAAGATTTGTTGCTCATTCTGTCCCTTCTCCCTTCCGTGCCTCTTTTCTCATCTCTTGTTCACCTGGCTAATTCCTGATCATCCTTTAAGACTCAGCTCAGACATTTCCTCCTCCAGGTGGAGACGTGCCCCACTTCTCACGCACTGCTCATGTTGTCCTAGCCTTAGCGCTGAGTCTGTGTGTGTTTATGTCCCCTGGTGCACTCTATCTAGAGTGATTTGTTCCACGTGTAAATTATCTTTCCTGCTATGAAAATGTAGCATTTGGCCGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTCTGGGAGGCTGAGGCGAGTGGGAATTCAGGAGTTCAAGACCAGCCTGGCCAATATAGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCGGGCGCCTATAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCTTTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATCGCTCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTCGTGGGGGTAGGGAAGGAAATGTAGGATTCTTTTTTTGATTTTTATTATTTGAATAATACTTGTTCATTTTAGAAATTAAGAGGACTTTTGTTTTATCTGTGAAAGGGTATGAAATATTCACCCCCAATCTCTGGAATAAGCATGTTAATAATTAGTTCCCCACTAAACACACAACCAAATTCAGTCCAGTTCAGCTGACATTGTTGAACAACCGTGAAGTATTAGGCACTACAGCCAGTAAGGGGAGTAAGAGCCACCCCTTTCCTCAAGAAGCCATCAGCCTTTGTGGGGGAAAACTTGTACAGTAAAAGAAGTCCTTAGGATGCTCAGTGCTTTCCTAAGGGCAACGTGGGAGCACTAAGGAAGCAGTAGTCTCCTCAGGGAGTGGTTGGGAATGGTTCCCAGAGAATGTGCTGTTTCAGCCAAGTCCTGAAAAGGATGAGGAAGAGTTCACCAGGAGGCAAAGGGATTGGCCATACGAGATGAGTGCAGAGGTCTGGAGACATGGGATATTGTGGTTTATGCCCATTGTCTGTTTGAGTGAAGTAATGACCCTGAGGTATAACTGTTACTATCCCCGTTTTACAGATGAGGAAAGCCAAGCTCAGGTAAATCAATTGGCCTAAGGTAATACTAGTAAAAAGTCAATGTAAACTTGGGCTTTCTGACTCACAGTATAATGCTTTCTCATTAAACATAATCTGCTGTAGTAGAACCTGGCTGTCTCACACTGGACACAGACTGTACAGATTTAAAAACAAATTTGCTAAAAATTGTGAAATTGCTACAAAAAATGTATATTTTGTGCTATTCTATATATGCAGTGATTTGCTTTGTCAGGGTCAGGATTTGTTCATTGCATAAAACGAATATGATTTCACATTTAAGTGGAAAATTGAATTAAGGCCCAGTTTGTGGACCACCATTTCTAACCATGTCCTTTCTCAAAGTGAGTTTAAACCAGGTAAATATGAAGTGAAAAGGAAGATGCAGTTGAGATTAGAGACCTAAGTTGTGTTCATTGGTATTTGTACTCATTTCACTCATTGGGATTTTCCTGGTACAG
Seq C2 exon
TACCTCAGCCAGACCCCAACCAGCCCAAGCCGGAGGGACGGCAGATGACCCCTGTGAAAGGAGAGCCTTTAGGAGTCATCTGTAACTGGCCTCCTGCTCTTGAATCTGCCCTGCAGCGCTGGGGTACCACTCAAGCAAAATGCTCCTGTCTGACTGCACTGGACATGACAGGGAAACCAGTTTACACTCTTACATATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000066084-DIP2B:NM_173602:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.724 A=NA C2=0.286
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0050123=AMP-binding=PU(16.6=37.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)