HsaINT0048741 @ hg19
Intron Retention
Gene
ENSG00000108813 | DLX4
Description
distal-less homeobox 4 [Source:HGNC Symbol;Acc:2917]
Coordinates
chr17:48050130-48051951:+
Coord C1 exon
chr17:48050130-48050633
Coord A exon
chr17:48050634-48051064
Coord C2 exon
chr17:48051065-48051951
Length
431 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
3' ss Seq
TTCCCCTTTTCTTCCCGAAGGTA
3' ss Score
10.23
Exon sequences
Seq C1 exon
CCGCAGGCGCCGCGGTACCCTGGCTGTGGCCCTCGGCGCTTTCTTCCTAGGGTCACAGGACCCATACGAGTGGGAGCTCCCTGGGAGCAGAACTGCGTCTTGTATCACCTGGCGCGGTGAACGTGGGGGTTGAAACGCTCCACGCGGAAGGTAGAGGGCAGGGGCCAAGGGGGCGATCCTGGTGGCTGCGCTTTTTGCTATTTGCTGCCGACGGCATGCAGACGAGATGCAAATAAGCTTATGAAACTGTCCGTCCTACCCCCTCGCTCCCTCCTCGCCCCCTACACCGTGTTGTGCTGCCCACCAGACTCGGAGAAGCCGCGGCTGTCCCCGGAACCCTCCGAGCGGCGCCCTCAGGCCCCCGCCAAAAAGCTCCGCAAGCCGAGGACCATCTACTCCAGCCTGCAGCTGCAGCACCTAAACCAGCGTTTCCAGCACACGCAGTACCTGGCGCTGCCCGAGAGGGCCCAGCTGGCAGCGCAGCTCGGCCTCACCCAGACCCAG
Seq A exon
GTGGGGCCAGTGTCGTCCTTCCCCATCTCTCACCTTCCCTGGTTCTCTGGGAACTCATCCCCCAGCCCCAGCTGTGAATGACTGATGGATTGGTGCTGTGGCCCTGTTGTCACAGTTCTCCAGGGAATGTTCATAGCTGGCTCTTAGTAAGCCTTGGGGGGAATGTGTTGAAAGGTGTGCATGTATGTGCGGGTGGGGTGGAGTGGGTCAGGAAGAGGAGGGTAGGTCAGACAGGGAGACATGGATACTAGCTCAGAGGCAGGAACTCAGAAGGCTCCTGGGGCTGTGGGGGACTGAAGCAAATGTTCCCAGCCTAGGGAACTGCTGGTCTCCCAGGACTGTGCCTGCACCTGGATCCCTTTCCCTTCCTCGAAACTTTTCACACATATCTTCCTCCTGATCTTTCATTCTTTCCCCTTTTCTTCCCGAAG
Seq C2 exon
GTAAAGATCTGGTTTCAGAACAAACGCTCCAAGTATAAGAAGCTCCTGAAGCAGAATTCTGGGGGGCAGGAAGGGGACTTCCCTGGGAGGACCTTCTCTGTGTCTCCCTGCTCCCCACCCCTCCCCTCCCTCTGGGATCTACCCAAGGCAGGGACCCTGCCCACCAGTGGCTATGGCAACAGCTTTGGAGCCTGGTATCAGCATCACTCCTCAGATGTCCTGGCTTCGCCTCAGATGATGTGAATCTGGGGAAGGGCGGGTCAGGCCCACAGCCTTCCTGCAAAGCCCAGGACCCAGGCAGTCCACCTGCACCCCTTCTGGGCTGGGAGGAAACCAGCTCCAGATGGGTTTTCTCTGGAGGACAAGCAGTTAGAGGAGAAAAAGGAATGGAGCAGAGCCTGTACCCCTAACCCTAACAGCTAAATCAAGGACCTCAGCCTTATATAATCATTGTCCCCACCACTACCATGGACTGGACACCTTCACTCCAGCTGGACAAAGACTCTGGAGAGAGAGCCATTGGCTGGAGTTGAGACTGTCCCCAGAACCCTTGGTCTTGCCACTCCCCCACTCCTTCTTCCCTCTCTCCCTTTCTCCTCTCCCTGCTTTCTTGAAAAGGACTGAATCGCCACTACAGCCTGGGTGCAAAATCAGCAAGAAACATTGAGTATTTTTTTTTCTTTGTATGCCTTTGGCCTTGCACAACCCATTTGTGAGCAAAAGCAGAAGTGGACCACCATCAGCTCCCACCCACCCAGCGATTTTTCCTTGGAGGTCAGCCCGTTACCCCCATAACTGATTTACCTACTTACCATACTGGGAGGTAGAAGAGATGCAGAGAAATGTGGAATTTGTGGACCTATGGGTAATTTATGCTTTCCTCCTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108813-DLX4:NM_001934:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.318 A=NA C2=0.275
Domain overlap (PFAM):
C1:
PF0004624=Homeobox=PU(73.7=47.7)
A:
NA
C2:
PF0004624=Homeobox=PD(22.8=16.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGCCGAGGACCATCTACTCC
R:
GCCAGGACATCTGAGGAGTGA
Band lengths:
350-781
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)