HsaINT0048741 @ hg38
Intron Retention
Gene
ENSG00000108813 | DLX4
Description
distal-less homeobox 4 [Source:HGNC Symbol;Acc:HGNC:2917]
Coordinates
chr17:49973073-49974959:+
Coord C1 exon
chr17:49973073-49973269
Coord A exon
chr17:49973270-49973700
Coord C2 exon
chr17:49973701-49974959
Length
431 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
3' ss Seq
TTCCCCTTTTCTTCCCGAAGGTA
3' ss Score
10.23
Exon sequences
Seq C1 exon
ACTCGGAGAAGCCGCGGCTGTCCCCGGAACCCTCCGAGCGGCGCCCTCAGGCCCCCGCCAAAAAGCTCCGCAAGCCGAGGACCATCTACTCCAGCCTGCAGCTGCAGCACCTAAACCAGCGTTTCCAGCACACGCAGTACCTGGCGCTGCCCGAGAGGGCCCAGCTGGCAGCGCAGCTCGGCCTCACCCAGACCCAG
Seq A exon
GTGGGGCCAGTGTCGTCCTTCCCCATCTCTCACCTTCCCTGGTTCTCTGGGAACTCATCCCCCAGCCCCAGCTGTGAATGACTGATGGATTGGTGCTGTGGCCCTGTTGTCACAGTTCTCCAGGGAATGTTCATAGCTGGCTCTTAGTAAGCCTTGGGGGGAATGTGTTGAAAGGTGTGCATGTATGTGCGGGTGGGGTGGAGTGGGTCAGGAAGAGGAGGGTAGGTCAGACAGGGAGACATGGATACTAGCTCAGAGGCAGGAACTCAGAAGGCTCCTGGGGCTGTGGGGGACTGAAGCAAATGTTCCCAGCCTAGGGAACTGCTGGTCTCCCAGGACTGTGCCTGCACCTGGATCCCTTTCCCTTCCTCGAAACTTTTCACACATATCTTCCTCCTGATCTTTCATTCTTTCCCCTTTTCTTCCCGAAG
Seq C2 exon
GTAAAGATCTGGTTTCAGAACAAACGCTCCAAGTATAAGAAGCTCCTGAAGCAGAATTCTGGGGGGCAGGAAGGGGACTTCCCTGGGAGGACCTTCTCTGTGTCTCCCTGCTCCCCACCCCTCCCCTCCCTCTGGGATCTACCCAAGGCAGGGACCCTGCCCACCAGTGGCTATGGCAACAGCTTTGGAGCCTGGTATCAGCATCACTCCTCAGATGTCCTGGCTTCGCCTCAGATGATGTGAATCTGGGGAAGGGCGGGTCAGGCCCACAGCCTTCCTGCAAAGCCCAGGACCCAGGCAGTCCACCTGCACCCCTTCTGGGCTGGGAGGAAACCAGCTCCAGATGGGTTTTCTCTGGAGGACAAGCAGTTAGAGGAGAAAAAGGAATGGAGCAGAGCCTGTACCCCTAACCCTAACAGCTAAATCAAGGACCTCAGCCTTATATAATCATTGTCCCCACCACTACCATGGACTGGACACCTTCACTCCAGCTGGACAAAGACTCTGGAGAGAGAGCCATTGGCTGGAGTTGAGACTGTCCCCAGAACCCTTGGTCTTGCCACTCCCCCACTCCTTCTTCCCTCTCTCCCTTTCTCCTCTCCCTGCTTTCTTGAAAAGGACTGAATCGCCACTACAGCCTGGGTGCAAAATCAGCAAGAAACATTGAGTATTTTTTTTTCTTTGTATGCCTTTGGCCTTGCACAACCCATTTGTGAGCAAAAGCAGAAGTGGACCACCATCAGCTCCCACCCACCCAGCGATTTTTCCTTGGAGGTCAGCCCGTTACCCCCATAACTGATTTACCTACTTACCATACTGGGAGGTAGAAGAGATGCAGAGAAATGTGGAATTTGTGGACCTATGGGTAATTTATGCTTTCCTCCTAAAAAAAAAAAAAAAGCCCTCTTTCCCACCCCCTCCCCATCTCCCCTTTTTGAATAGATAATGGATCCAATTATCCATATAATTCAATAGGTATTTATTGAGAGGCTCCCTTCTATTCCCCATCCCTAATCCCTAACGAACCCACGGGCACACACTTTTGGAAACCTGGTAAAGTAACACTTAGGGGGAAATGGGGACAAACTGGCTCTCTGGATTAGTGCGGGTATAGACACCCCCAAATAGGTGGGTAGGCCCATTGATTCAGCTCCTTGCAGCTGTCTCTGTTCAAAGGAACTGTGCAGATTTAGAACGAATTGGAGCTTGAGCTTCACACCACCAGCTTCCAGAGATTAAAGTTTGTACAAAACATTGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108813:ENST00000240306:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.374 A=NA C2=0.275
Domain overlap (PFAM):
C1:
PF0004624=Homeobox=PU(73.7=63.6)
A:
NA
C2:
PF0004624=Homeobox=PD(22.8=16.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGCCGAGGACCATCTACTCC
R:
GCCAGGACATCTGAGGAGTGA
Band lengths:
350-781
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development