HsaINT0048742 @ hg19
Intron Retention
Gene
ENSG00000105880 | DLX5
Description
distal-less homeobox 5 [Source:HGNC Symbol;Acc:2918]
Coordinates
chr7:96651497-96654143:-
Coord C1 exon
chr7:96653581-96654143
Coord A exon
chr7:96651682-96653580
Coord C2 exon
chr7:96651497-96651681
Length
1899 bp
Sequences
Splice sites
5' ss Seq
CAGGTACAT
5' ss Score
7.79
3' ss Seq
AGTCTGTTTTGATTATTTAGAGA
3' ss Score
5.01
Exon sequences
Seq C1 exon
AGCAGTCAGCCGGCCGGAGACAGAGACTTCACGACTCCCAGTCTCCTCCTCGCCGCGGCCGCCGCCTCCTCCTTCTCTCCTCCTCCTCTTCCTCCTCCTCCCTCGCTCCCACAGCCATGTCTGCTTAGACCAGAGCAGCCCCACAGCCAACTAGGGCAGCTGCCGCCGCCACAACAGCAAGGACAGCCGCTGCCGCCGCCCGTGAGCGATGACAGGAGTGTTTGACAGAAGGGTCCCCAGCATCCGATCCGGCGACTTCCAAGCTCCGTTCCAGACGTCCGCAGCTATGCACCATCCGTCTCAGGAATCGCCAACTTTGCCCGAGTCTTCAGCTACCGATTCTGACTACTACAGCCCTACGGGGGGAGCCCCGCACGGCTACTGCTCTCCTACCTCGGCTTCCTATGGCAAAGCTCTCAACCCCTACCAGTATCAGTATCACGGCGTGAACGGCTCCGCCGGGAGCTACCCAGCCAAAGCTTATGCCGACTATAGCTACGCTAGCTCCTACCACCAGTACGGCGGCGCCTACAACCGCGTCCCAAGCGCCACCAACCAGCCAG
Seq A exon
GTACATGGACAGGGGGAAGGCTGGGCAGATACAGGGCGACTAGGACGCTGGGGGCGCGAGATGGGGTGGTAGATTGGGGGTCACAGCGGTTCACGGCAGTGGGGGCGCACGCGGCAGAAGGGAGTAGGACTCAGACCCTCCAACAAAGAGAGTTTCTCGGGCCAGCATTTTAGGGATTTTTAGTAGGAGAGCCCTGTGGAGGTTCGAACTAGCGTCTCTCCCCTCCGGCACCTTCCAAGGCCCTTCAGTCGCTGAATTCCCAGCTTGCCCGGCCAGGAAGCCGGCTAGGCTGGAAAGGGGATAGGGGTGGAGAGAAGAAAGAATCAAGCAGCTCCTGGCGTTTGCGTAACAAAGAGAAGGTTACTTGGGAATTTTGGTAAGCGTGCTGGGTTGGTGCGAGTGGGAATAGAAGGCTGCCTCAAAAACTCAGTCAGGATTAGTTTGAGAGCCGCCACAAGCTAGCACGGTGCGGGTGCCCTGAGCACGCTGGGTGGGGGTGGGGGGGTTAAGGAGTTGTAGCCAGCCAGAGAAGAGCGCGCCGAGAGTTTTGCGGTTTATCCAGGCATTTCCAAAAACAAAAAGCCATTTAAAGGTGGAGGAGGGTTGCTGAGGGGTCACGTTGTAGGATAGATTTTTTTTTCTGTCTCCATAGGCGCCCACAATTTGTCTTTCCGTCCTCCTTTTTCGTCCGCTTTGAAACTTACTTAGAGAGTTTAAGAGGGTTAGTGAGCTTGGGCGGTAAGAGAAAGGCATGAGGCTCGGCGGAGAGGTTTTATTGGTAAGGTTTGATCTCTTCCCACCAGCACATTAATAATCCTGCTAATATTAGCATCCCCTACTCTGGCAGAATTGAGACCACAGCCCTCATCCTCCACACTTCTCCCTGGAACTTGACACACACACACACACACACACACACACACACACACACCCTGGAGAGGTTCTCCGTCAGTTCCAGAGGGGTGGTAGTTTTGAGGAAGGGGAGTTGTAGCCCCAGGGCAGGTTTGTACAACACGCGTTTGGCAATCCCTCCCCCTCCCGCCCAAACCCATACTCATGACAGTGAGAATCTCATCCTGACCTGCCGCCCCTTTCCTACGAAAACACCCCACCACCGGTTCCTTCTCAGTGTGTGACTCTTGCTGAACTTTAAAAGAGAGCCCCGGGTTGAGGTGTCTACGTTTCTTTCACTCTCTCTGTATTCCGTGCATAAGTGGAAGATTTCTTTTTTTTTTTTTTTTTTTTGCCAAGAACATATTAAGTCTATTTGTAAAAGAAACCAGACACATCTGTGCCCTCGCAGATCTGCAGCGAGATTATGGGGGTTGCATAATCGACCCTCTGTCTGCGGCGGCCCCGACCGCTTGCTGCTGAAGTGAAGGAGCAGTTTGCTTGTGGGTCTTTGAACTTTGGAGACCTCGGTTAGCGTCTTCCCTGCCCAAGAGTCTGGCTTCTGCGGGCGCCCGAACAGACGCCGACAGAAGTAGGGTCACGGCCCAGGGCCACCTCCTTGAAGCCTGGGGAGGGGCTGGTGTTCTTGAAGCCTGGGGAGGGGCGGAAACGCGGAGGAGCACAGGGTGGGCGTAAAAACAAGTCCGGGAGAAGAAGCAACGACCGCAAGAGCTGAATCCCAGATGCCAAGGAGAAAGCAGTGTTGTAGGAAGCGCTTTGCACAAACTATCTGAATGAACAGAGTAGGAATTAATCAGAGGCTATCCCGCTTTTCCATATTTGGGGTAGGTGCATATTTATCGCGGTCCTGAAAAGCAAAGGTGGTGGTGATATGGGCAAAGAATGAAGACTGAGTGGTAAGAAACTCTAGGACTCTATTTGAGGCCCTTCCGCAAAAGGGGCATTGTCTGGTGACAAGCTTTAACTGAGTCTGTTTTGATTATTTAG
Seq C2 exon
AGAAAGAAGTGACCGAGCCCGAGGTGAGAATGGTGAATGGCAAACCAAAGAAAGTTCGTAAACCCAGGACTATTTATTCCAGCTTTCAGCTGGCCGCATTACAGAGAAGGTTTCAGAAGACTCAGTACCTCGCCTTGCCGGAACGCGCCGAGCTGGCCGCCTCGCTGGGATTGACACAAACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105880-DLX5:NM_005221:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.445 A=NA C2=0.323
Domain overlap (PFAM):
C1:
PF124133=DLL_N=WD(100=73.1)
A:
NA
C2:
PF0004624=Homeobox=PU(73.7=67.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACCTCGGCTTCCTATGGCAA
R:
TTTGTGTCAATCCCAGCGAGG
Band lengths:
353-2252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)