HsaINT0049211 @ hg19
Intron Retention
Gene
ENSG00000114841 | DNAH1
Description
dynein, axonemal, heavy chain 1 [Source:HGNC Symbol;Acc:2940]
Coordinates
chr3:52433561-52434513:+
Coord C1 exon
chr3:52433561-52433795
Coord A exon
chr3:52433796-52434340
Coord C2 exon
chr3:52434341-52434513
Length
545 bp
Sequences
Splice sites
5' ss Seq
CTGGTATGA
5' ss Score
6.69
3' ss Seq
CCCCTCCTTGCCCATTCCAGGAA
3' ss Score
10.38
Exon sequences
Seq C1 exon
GTGATGTTTGAGGCACCATCAGAGTTAACACAAAGACCCCAAGTAGGGTGCTATATCCATGGATTATTCCTGGAAGGTGCCCGCTGGGATCCAGAGGCCTTCCAGCTGGCTGAGTCTCAGCCCAAGGAGCTGTACACAGAGATGGCCGTTATCTGGCTCTTGCCAACACCCAACCGCAAGGCCCAGGACCAGGACTTTTACCTGTGCCCCATCTACAAGACACTGACTCGTGCTG
Seq A exon
GTATGAGGCCTGGGATGGGAGCCTACACTATGGGCGGGGACCCAGGACTAACCCAGCCCAGCCCAAGCCAGTCACTTATCCAGGTTAGCTGAACAAGGAAGGACAACAGAGATTTGGGCCAGGCCAGCAAGCAGCAGGCAGGTTAATGCCCAAGGCCTGCCGTCTGGCTGTGGGGAGCACCCCTGAACTCCTATCCTGCATGCCTCCCTCAGCAGGCCCACCTTGGGCCCCAAGAGCCTACAAGCCCCAGCCTGTCATTGGGAGTTCAGAGGGGTAACTGAGGCCCAGGGCAGGAACTTGTTTGGACTAGGTCCATCAGAGAATGAAAAGTGGCATCAACTCTGCCATCCCTATCTTCAGTCCCCAATACAGTAACCCTGGGCAGGCTTGAACCCTGGCCAGACCCCCTCATCAGGTAGGCTTCCTCTTGGGTCAGGGCCCCCTCCCTGTCCTCAGCTTAGTCTGCCCACTGCCCTGCCCCTACGCTATCCCTGCTAGTAGTAATAGGGCATGACCTAACCCGTCCCCCTCCTTGCCCATTCCAG
Seq C2 exon
GAACACTATCAACCACAGGACACTCTACCAACTATGTCATTGCTGTGGAGATCCCCACCCATCAGCCCCAGCGACACTGGATAAAGCGTGGTGTGGCCCTCATCTGTGCCCTGGACTACTAGACTCAGACAGAAGGGCTGGGGCCATTAAAGCTGAATTTTCTAAGCAGTCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000114841-DNAH1:NM_015512:77
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.028 A=NA C2=0.104
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(11.0=100)
A:
NA
C2:
PF0302810=Dynein_heavy=PD(5.1=87.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTTTGAGGCACCATCAGAGT
R:
TAGTCCAGGGCACAGATGAGG
Band lengths:
349-894
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)