HsaINT0049268 @ hg19
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein, axonemal, heavy chain 10 [Source:HGNC Symbol;Acc:2941]
Coordinates
chr12:124397645-124399097:+
Coord C1 exon
chr12:124397645-124397862
Coord A exon
chr12:124397863-124398875
Coord C2 exon
chr12:124398876-124399097
Length
1013 bp
Sequences
Splice sites
5' ss Seq
CAGGTTAGC
5' ss Score
4.9
3' ss Seq
TCCCTCTCCTCCCGTGCCAGGTG
3' ss Score
10.72
Exon sequences
Seq C1 exon
GTGGCCAGGCTGGAGCGGAATTTTTACCTCACTAAACGGGAACTGGAAAGGATCCAGAATGAGTTGGCAGCAATTCAGAAAGAGCTGGAAACATTGGGTGCCAAATATGAGGCCGCCATACTGGAAAAGCAGAAGCTGCAGGAAGAAGCCGAGATCATGGAGAGGCGGCTGATTGCCGCAGACAAACTCATCTCGGGTCTGGGGTCAGAAAACATCAG
Seq A exon
GTTAGCGCTGCTCACGAGCCCACCTGTTGCGGTTTGTAAACGGACGTCACCCACAGAGTTTCTCGCCATGTTGATTCTTTATCTCACGTTGTGTTTTTATGTGAAAACCATGTGACCAGGTCTTATGTTCCTATTATCATGTTTATGGCAGCTAATGGCTATTTTATAGGCTCTTGTTTGTATTAGGCACTGAGTGTTATTTATTAATTACTAAGGGTCAAGGAGGCAGTGCAGCTGTGGAGACGGGGGAATCCATACCATTTAGCAGGGTGCTCTAGGTTTGGGAAGTGTTCACTTCTTGGTGACCTCTAACCCCTGGGTCTTTTCTAGAAGAGTCTGTGGGAGAAGCCCATCTCTGTCACCGCACAGATGCCTTCTAAGGGTCCCAGTGGCTTGTTCAATCCTGGGCTTCAGTCTTAAGTGATGGGGCTGTTTGATATTTATGGGCAAGACCGCTTGGCCACAGCTTATTCACCAAATAGGGCAACAATTTTGAATCTAGCATCTGTAAGTGTGGTGTAGAAAACACTGAAAAATGTTGTTTGCGTGTGGGAAACAATTTTCAGTATTTCTTAAACCTAAGTCTTGGGGCATTTACTGAAAGAGGACAAATGAAACAGACGCTTTCTTTTATCTTGGGTGGAATTCTGTCATTGAGTGAGGCCAGAACTTGTTAGCTCTGCCGGGCTGATTTATATGTCTTTGATTAAGGCTTCAGAAACAACGTGATTACTACTTAATATGATCCACGCAATGTGATTACTGCTTAATAAAGACCACAGGCCTTTACTGAGCCCCCTGCTTGATGCTGGCTCCAAATACCAGGTTCACTAGGGTGGGAAGTTGCAAGATAAGCTGTTGGTCTCTGTTCCTCACAAGGAAAGAATATCTCAAAACATGTTTCCATCTGGCTAGCCCTGTTAGCAAGGTATCAAGCTGGTTCTTCTGGAATGTTCCTTTTGGTTGTGGCCAGAAGGTAAACTCACGGCAGCCTCCCTCTCCTCCCGTGCCAG
Seq C2 exon
GTGGCTGAACGACCTGGATGAGCTGATGCACCGGCGCGTGAAGCTGCTGGGGGACTGCCTGCTCTGCGCGGCTTTCCTCAGCTACGAGGGAGCCTTCACCTGGGAGTTCCGTGACGAGATGGTCAATCGGATTTGGCAAAATGACATCCTGGAGCGGGAGATCCCCCTGAGCCAGCCTTTCCGGCTGGAAAGCCTGCTCACGGATGATGTTGAGATCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653-DNAH10:NM_207437:59
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127772=MT=FE(31.5=100),PF064196=COG6=PD(43.2=68.9),PF097264=Macoilin=PD(55.7=86.5)
A:
NA
C2:
PF127772=MT=PD(14.5=65.3),PF127812=AAA_9=PU(3.9=12.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGCTGGAAACATTGGGTGC
R:
CATCATCCGTGAGCAGGCTTT
Band lengths:
347-1360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)