HsaINT0049275 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123923763-123924432:+
Coord C1 exon
chr12:123923763-123923867
Coord A exon
chr12:123923868-123924277
Coord C2 exon
chr12:123924278-123924432
Length
410 bp
Sequences
Splice sites
5' ss Seq
AAGGTAATG
5' ss Score
8.99
3' ss Seq
TTCTCTTCTGTTGTGATTAGGAA
3' ss Score
9.18
Exon sequences
Seq C1 exon
GGCTGTTTGAGAGGCACAAGCTACTCTTTTCTTTTAATATGACCATCAAGATAGAACAAGCAGAAGGGAGAGTCCCTCAAGAAGAACTAGATTTCTTTTTAAAAG
Seq A exon
GTAATGAATTTGCCTAGCTTCATTCCTCCCATCTCCTTGCCCACATGATACATGTATATAAGTTTGTCTGTTGAAACAAACAATAACAAAAATTCTCCTTAAAACTTGGCTTCCAACAGCACTGCATTTTTCACTATTCCAGTTGATCATTCCAGCCTCAGAAATGGCTCTGGTTGAAATCGGAGCAGCCAGCCTCTGTCTCGGGGCCATCCTGAGGCTGGAAGCTGGATGCTGCACTGAGCGCCTGGTTGGTGTCACTGGCGGTGACGAGGGCAAGCCTGGGCCACTTCCTGTTTCCAGTCTCCTTCTTGAAAAGTGGACTTTTCCCAAAAGTGGGAGAAGTCGAAGCAGAGTTGCTTGCTTTGTGTTAGTGGTACAATGGCTGCTTGCTTCTCTTCTGTTGTGATTAG
Seq C2 exon
GAAACATTTCCCTGGAGAAAAGCAAAAGAAAAAAGCCCTGCGCTTGGTTGTCTGACCAAGGATGGGAAGATATCATTCTTTTATCAGAAATGTTTTCAGACAACTTTGGGCAACTTCCTGATGATGTTGAGAATAATCAGACTGTCTGGCAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:65
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0302810=Dynein_heavy=PU(6.6=90.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGTTTGAGAGGCACAAGCT
R:
AGACAGTCTGATTATTCTCAACATCA
Band lengths:
251-661
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development