HsaINT0049727 @ hg19
Intron Retention
Gene
ENSG00000158486 | DNAH3
Description
dynein, axonemal, heavy chain 3 [Source:HGNC Symbol;Acc:2949]
Coordinates
chr16:20952723-20955985:-
Coord C1 exon
chr16:20955818-20955985
Coord A exon
chr16:20952866-20955817
Coord C2 exon
chr16:20952723-20952865
Length
2952 bp
Sequences
Splice sites
5' ss Seq
CAGGTAACT
5' ss Score
8.63
3' ss Seq
TCTTCTGCCTGCATTTTAAGGAA
3' ss Score
8.99
Exon sequences
Seq C1 exon
TCCTATATCGACTATCTCAGGAATCTCCCCATCACAGCCCACCCAGAAGTGTTCGGCCTCCATGAGAACGCAGACATCACCAAAGACAACCAGGAAACCAACCAGCTGTTTGAGGGGGTCCTGCTGACCCTCCCTAGACAGTCAGGAGGAAGTGGCAAGTCCCCTCAG
Seq A exon
GTAACTGGGCTCGGGAAAGGGGGCTTAATCCTATTTCCCAGGCAGTTCTTCATCCAGTGGGCACACAGGATTGGAGGGTGACCAAGAGGCAGAGAGTGGGGGCCTGGCAGCCTCCTGGCCAAGGGCAGGGAAGGAGCACTGTGGCCTTACTGCCGGGAGTCCTTATATCCAGAGCTGCAAGGGAACCAGTGTTTCCAAAATGTCAGCTATTCCTGTATAACCTTCATGTTTTCTGCTATATCCACCTATCACCTATACTCCATTTACATAATGGGTTTTATTCTTTTTTTTTTTCTTTTGCTTTTTTTTCTACATAATGTTTTAAAACTAACTCTCTTTTTTTTTTAATTTAAAAGATTGCACATCAGAACCATAAGTGGAAACCCAGTATCATTTCCATAAAGTCATGATACGCACAAAAAGAAAATGAAAGCTGAACAGTGAACAGTTGGTGTTTTTTGGTTTCTGTTTGTTGTTGTTGCTGTTTTTCTTTTCTTTTCTTTTTTTTTTTTGAGACACGGTTTGGCTCGGTTACCTAGGCTGGAGCGCAGTGGCGTGATCTTGTCTCACTGCAACCTCCGCCTCCCAGGCTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAAGCACATGCCACCATGCCCAGCTAAATTTTTTTGTATTTTCTGTAGAGACAGTGTTTCATCATATTGTCCAGGATCGTCTCAAACTCCTGGGCTCAAGCAATCTGCTTGCGTTGGCTTCCAAAAGTGCTGGGATTACAGGCGTGAGCCACTGCTCCCAGCGTTAACAGTTGTTAAGTTCTTCCCAGATGATGTTGCTGGCCAAAGCCCCTGAGCTGAGGCTTTGCTGGCTTCTTGTTAAAAGGAGAAAGATGTGTGAGTGTCAAAGAATTGGCACTGACCCGAAACTGTCTTTTTGAGAGGAATGAAAAGAGAAAGATGGTCAGAACTGGAAAAGAGGCCAGGTGCAGTGAATCGCACCTGTAGTCCCAGCACTTTGGGAGGCTGAAGCAGGAGGAGCACTTGAGGCCAGGAGTTCGAGGCCAGCCTGGGCAACATAAGGAGACCGCATCACTACAAAAAAATTTTTTTTAAGTTAACCGAGGGCTGGGTGCCATGGCTCATGCCTATAACCCTAGCACTTTGGGAGGCCAAGGTGGGTGGATTGCTTGAGCCAAGGAGTTGGAGACCAGCCTGAGCAACATAGCAAAACGCCGTCTATACAAAAAAAAAAAATAGCTGAGCTCAGTGGCGTGCACCTGTAATCCCAGCTACTCAGGAAGCTGAGGTGGGAGGATCGCTTGATTCTGGGCTGTTGAGGCTGCAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTAGGCGACAGAGTGAGACCCTGTCTTAAAAAAAGTTAACTGGGTGTGGTGGTGCGTGCCTGTAGTCCCAGCTACTAAGGGGGCTGCGGCAGGAGGATCACTTGAACCCAGGAGGTCGAGGCTGCAGTGAGGCTGTGATCACGAGGCTGTGATCATGCCTTTGCACTCCCACCTGGACGACAGAGTGAGACACTATCTCAAAACAGTAACAACAACAATGAAAAAAAACCCAAAACCTGAAAGAGTAACTTTCTCACCATGTGACTCAACATGATTTTTCTGTGTCCTGGAAACACCTAAAATCCTGGGTACCTCTAGTAGTCCCAGTGCACTCTTTGTGATGACCTGACCCAGGCCACCCTCCTAAGTCTACAAATGAAGAGAGAAACAAATCCTGAGAGAGAAAGTGACCGGCTTCCAGGCTTTCATAAAATCAAGGACGGAGCCAGAACCAGAGCCACCGTCTCCTGACTCCACCCGCTTCCTCTCCCATCCCTTCCCTTCTCCACCTTCCAAGCTACCTCCTGTTTAACCCCTCCCAACTGTAGAATTTGCTAATTTGCTTTCATGATTTGGTTCCTAGTGCCATTAAGTATCACTGGTATGAAGGTAAACCAGCCTGGTTGGTGTATCCCGATGTAGGAGTGGAAATTCCCCTCACAGTGGGAAGAGGGAAAGAATTATACATCCCAGCCTCCCACATCCACAGGACCACAGGGTGTCTGTCTCTCCCACACTCAGGTCTTGTTCCTCCTTGAGCCTCGAGGCCTGTCCCCTCCCTACTTGGCTAAGCTGAGGGTTCTGTGCTTTTCTTGCTCCAATGCTGAAGAATGGCCTGCTGCTTTCCCAGGTGTCACGGGCACTGAGAAAGGGCCCCATGGCACCAGGAGCTAATCCTCAGGGGTCAGAGGCTGTGGGAGATTCTCACCTGGGTGTGACATTGAAGACAGAGGCTTAGTGCTGCCCTGAAGCTACCTGGCTGAGCAAGAGTTCCCTTCCTGGCCCTTCGGCTCTTGCCTGAGGTGTCAGGACACGACTCTTTTTTTTTTTTTTTTTAACTTTTAGACAGGTGTTCCTCTGTCACCCAGGCTGGAGTGCAGCGGCCAGATCTCAGCTCACTGCAACATCCGCCTCCTGGGTTCAAGTGATTCTCCTGCTTCAGCCTCCCAAATAGCTGGGACCATAGGCATGCAGCATCATGCATGGCTAATGGCTAATTTTTGTATTTTTTGTAGAAACTGGGTTTCGCTATGTTTCCCAGGCTGGTCTCAAACTCCTGGACTCAAGCGATCCACCCACTTCGGCCTCCTAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCTCTGCCAAGGACAGGACTCTACTCTTCTGGACCAAGAGGCGATGCCCTCCCCAAGGCTGGTGGGGTGATGAGGGACTCCTTTCCCCACTGGAGGCAGAAATGGCTTCTGTTGGAGAGTTCTCAGGAAAGTCCCACAGAATACATTTGAAAAGTCAGATGCTCAGTACTTAAAGTTTATCCAAAGCCACAGCCTGTAGGGCTTGCTTCTCACTCACCTCTCTTCTGCCTGCATTTTAAG
Seq C2 exon
GAAGTGGTTGAGGAGTTGGCACAAGACATTCTCTCCAAGCTTCCCAGAGACTTTGACCTGGAAGAGGTCATGAAGTTGTACCCCGTGGTCTATGAAGAATCCATGAATACCGTCCTAAGGCAGGAGCTCATCAGATTCAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-DNAH3:NM_017539:58
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.125 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(7.7=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(6.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)