HsaINT0049730 @ hg19
Intron Retention
Gene
ENSG00000158486 | DNAH3
Description
dynein, axonemal, heavy chain 3 [Source:HGNC Symbol;Acc:2949]
Coordinates
chr16:20946670-20948175:-
Coord C1 exon
chr16:20947971-20948175
Coord A exon
chr16:20946808-20947970
Coord C2 exon
chr16:20946670-20946807
Length
1163 bp
Sequences
Splice sites
5' ss Seq
CAGGTACCT
5' ss Score
8.16
3' ss Seq
TGATTTCTGTGGCTCTCCAGGAA
3' ss Score
9.45
Exon sequences
Seq C1 exon
GCTGACCAAAGTGGTTCGGAGGAGCCTCATCAATCTTGGCCGAGCCATCAAAGGACAGGTCCTGATGTCCTCGGAGCTAGAGGAAGTCTTTAACAGCATGCTTGTGGGTAAAGTGCCAGCCATGTGGGCAGCCAAGTCTTACCCATCACTGAAGCCTCTGGGGGGCTACGTGGCTGACCTGCTGGCCCGCCTGACCTTCTTCCAG
Seq A exon
GTACCTGGGAGTCAGGGGTAACCGGGAACCTGGCATGCTTGCTTAGGTGGAGAGGACATTCTGAAATGGCAGACTAGAGGCAGGGGGAGGAGGGCAGGCAGCCACAGAACATCCTGGATTGAGCCTCTGGAAACAGTCTTCCTGGAGTTAGAAGCAGGAGGGAGACTTGAAAGTCCTGGAAAAGATTATAGCCGGCCGGGCGCAGTGGCTCACATCTGTATTGCCAGCACTCTGGGAGGCCGAGGCAGGCGGATCACTTGAGGTCAGGAGTTCGACACCAGCCTGGCCAGCATGGTGAAACCCCGTCTCTACTAAAAATACCAAAAAAATCAGCAGGGCATAGTGGCTTATGCCTGTAGTCTCAGCTACCTGGGAGGCTGAGGCAGGAAAATGGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATCACGCCATTTCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTAAAAAGAAAAAAAATGTCACAAACTGGTGGCTCATGAGATAGATTTGGACAATAATTATGTTTGGTTTGGCTACCTGGTAATTTAAACATTTTTGAGCCAGCATGTAAACATTGATTTTTTACATATAAAAATCCGATGTTTGTACTGCAAAAAATAGAAGACCTGAAACAATGCACCTGCGTTCTCGCATGGCATGGCGACTATTGCTGGAGATGAGTGGCAGCTGCTCAGTTTAGACAAGGTACATATTCTCCACTGCTACAGTCCCCACCACTCTCTGTTGTATCCCTGATATCAGCTTGCACCTGGGCTTTTTTTTTTTTTTTTGAGATGAAGTTTCACTCTTGTCACTCAGGCTGGAGTGCAATGGCATGATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCTTCCCAAGCAGCTGGGACTGCAGGTGCCCACCACCACGCCTGGCTAATTTTTGTAGTACCTAGGCGTTTCTTAAAGTGTAAATATATTTCTTTGTACCCTTATTTCAAAAGTGGGAAGATAGAAGCTAAACCAAGAGGGCTGTTTCAAGAAAAATATGAAAAAACATATTTTATATGGTACTCGTTACATTACTTGCATTTGAACTATCTTTGATGTGTTGTTGATTTTGAATCTTGATTTCTGTGGCTCTCCAG
Seq C2 exon
GAATGGATTGACAAGGGGCCCCCTGTGGTATTTTGGATCTCTGGATTCTACTTCACACAGTCTTTTTTGACTGGCGTCTCTCAAAATTATGCCCGGAAATATACCATCCCCATTGACCACATTGGATTTGAGTTTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-DNAH3:NM_017539:60
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(9.6=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(6.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAAAGTGGTTCGGAGGAGC
R:
AACTCAAATCCAATGTGGTCAATGG
Band lengths:
334-1497
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)