HsaINT0050024 @ hg38
Intron Retention
Gene
ENSG00000124721 | DNAH8
Description
dynein axonemal heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:2952]
Coordinates
chr6:38931811-38935697:+
Coord C1 exon
chr6:38931811-38931993
Coord A exon
chr6:38931994-38935591
Coord C2 exon
chr6:38935592-38935697
Length
3598 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATC
5' ss Score
6.99
3' ss Seq
TTTTTGTTTTTTAATGACAGGAG
3' ss Score
6.99
Exon sequences
Seq C1 exon
GTGAAAGTCGGTGATAAGGAATGTGATATCATGGATACATTTAAACTTTACATTACTACGAAGTTACCAAATCCTGCCTTTACCCCAGAGATTAATGCTAAAACGTCAGTCATTGATTTCACTGTTACAATGAAAGGACTTGAGAATCAGTTACTAAGGAGAGTCATTCTAACAGAGAAACAG
Seq A exon
GTAATCTCTCTCTCAAGGTAAAGAATTTCTGCTTATAATACATGCTTAAAATGTATTGAGAAATTGCTAAGTATGTGAAAAAGAAAAAAAAATTTAAAAACCATATTTATCCTTGTTAACATAAGTATTTCTTTTGCAGCCTTAATTCCTGTCAAGAAATCATGTAACTCATCTTCTCATCCAGCCTGAAACACACACACACACACACACACACACACACACACCCGTCTCTTTCTACTTCTGTCTTTAAACTTCTAGGTGTACTGACTCTCTTATGTATAGTCCTTGTCTTGGGGACACCTGAAAACATCAATAAAACAATGATTGAGAGAAAAAGAAATTCCTCTGAATGGCTCTTCTTTCCACTGTAGTAGTTTCAACTACTACAGTCCAATAATCTAATGATATAGGGAGCCATACCTTTATTTTTAATTAAATTTTCCTGCACTAAAGCAGGGAAATTATGTCTAACTGAGGGTTCTAATAAAACAAAGAACAACTTAGGACTGGAAGATTTTAAGAGACTGATACAAGATTAAACTAATTTTTAAGTTGAAGCTCAGAAAACATTGTTTTATGCATAAAATATAATTGCATAAAATATTTTATGTATCTGCATTATAAAGTACATTTGCATAAAATATGATAAAGTAATTAATTTTAGAATTAAAGATTCAAGACAAAGGCAAGGTTAGAAATAATAAGAGCAGCAAGGCATGAAGTGGATGGGTGAGAAAAAGAATGACAAGGGAGGAAAACAGACAGAGGAGGGAAAAGAGGAGATGTGAATCCAGGGTCCCAAACACAGGAGAGACATCCAAGAAGGGAGAGGGAAATGACACAGACACCAAAGAAGTAGACTCAGTGAAAGGCAACATCCTACCTGGCTCATAGACAGTTACCACAGGCACAGGCCCTTGAAAGGTGGCTGGTCTGGTGGAGTGAAAAGGGCACAGTCTCAGCTTTGACTCTCTTAGTTGTTTGATCTTGGTTTCCAACAAACCTGGGGCTTATGCAGTCCAGGAAGGGATCCCGTTCCTCTTCCACAGCCAGGCGGAGATGGCCCTGGCCCGGCAATTCACTGTTTCCATCGCCTCTCAGGATCACATGCTGTTAACTGTTGACAGTTAGTCCCTTGTGGTCTAATTGGTGCTGTGGGTTTATTTTGAGATGATTCCTCGCTGGTCTAGATCCCCCATGCAGGCTGCACTAACCTCCAGAAGTCAAGCAACTCCACTGTCTAAAGGTCCCCAGGGCTCCCCACACCCACTCTTCTTATTCCCTAGCTTCCTCTTCAAGAGATGTGCTAAGATGCTCATAGCAACCTTGCTGGAGAAAAAAATGCACATTTAATATGCAGGAGGGTATTCTAAACATTATATTTAACCCTCCTAACAATCCTACTATTATACCCATATTTTTACAGATGAGCAAATGGAGACCAAAGAAAATAAGGGTCTCGGTCTGTAACAGCACATGGACTTTGCAGCCTGCCAAGCCTCCTAGATAAGGTTTACAGGTCCTGCTATGAAGTTTAGCAAGAGTCCACTGTGCTATGATATCTGTTTTTCCATATCCAGAAAAGGAAGCTAATATGATTTCATTTTGTCCATGTATTCCTATACTGCCACCCAGGGGTGACCATTTTAATGAAAATGACTAACTGGTTATTTCCCTGCAAATACAGCAATGCTCTTTATCGCCCCATCAACTCCTGCCACCCTGTAAGTACAATGGCAATAACACTAGTCTTGGAGTTGGAGGACAAGGGTATTAGGCTGTTTTAACACACAGCTAGTTACTGGCAGAGACCGGCCTAATACCCTTGTTATTCAGAGTTCATATTTCTGGGTCCTTGGCTTTTCCAAATGTAAAATAAAGAAATTGGACTAAATTCAGCACATTTCAGTTTGACAAATATTTATTGGGTTGAGTTTCTTCTTTACAAAGCCACAAGATAAGTACTGTCAATAATACAAAAATGAATAGGAAAGCTTATGTATCTGTTTTCTAGATGCATAAACCGTAGTTGGAGGGAAATAATCTACTGATAGATTGTGATACAAACTATATTAGAGGCCAGGCGTGGTGGCTCACCCCTGTATTCCTAGCACTTTGGAAGGTTGAGGCAGGTGGATTACCTGAGGTCAAGAGTTTGAGACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCACGCCTGTAGTCCCAGCTACTCGGGAGTCTGAGGCAGGAGAATTGCTTGAACCTGGGCGGCAGAGGTTGCAGTGAGCCGAGATCACACCACTGTATCCTAGCCTGGGTGTCAGAGGGAGACTCCATCTCAAAAAAACAAAACAAAACAAAACAAAAAACACGCACAGAAAAAAATCACAAAAAAACAAAAAACAAAACAAACTACATTAGATGTACAGATGAAGGCTGTGCCATGGCTTTTGATTGACTGGTTCAGGAAGACTTTTTGAAAATGATGAAATTTCTGAAGCAATTTTCCCAGAAACCTTCCCAAATAAGTTTTAAAACACCTTCTTTTAACGTAATTCTAAGTGCAGCATGTGATTCTGTATAAAATCAGAAGAAAAATGTTGTAAGGAATATTATTGAGATTATTGAGATTTCAATGTAGACTCTGTGTTTAGTGAGAGTATCAGTGATACTGACACATCAGTATCAGTGTTAAATTTCCTGAATTTGAATATTGGGCTACACTTATGTAAAAGAATGACCTGGTTCTTCAGAGATTTGCTAAAGTGTTTAGGGGTAAAAGGACATGACATCCACGAGTGATTCAGCAGTAATAATAATGATAACAACAATAACAATAATGACAACATTATGTATTCTATAGAGATATAGTGATAAAGCAAAATGTGATTTGGTGAATCTAAGTGAAGGCTATATGAAAGTTCCTTGTATTAGGCTTGCAACTTTTTGAATGCTTGAAATTTTTTCAAAATATAATTTTAAAAATATATCATTTTATGTAAGAAGAAAAAAACTCCTGTAAACATTCAAGTTTGCCCTCTGTAGAAGGAGATACAAATAAAATGGAAAATGGGTTTGTATTGGCAATCGGCTGTGCCAAACCAGGTACCTGGTGCTCCCATAGGAACCAGGCCAAGAGCTCACATTTAATCTGGGTAGCCCCTTGGTTTCTTGGTATTATTGCCTTTTTGTTTCTACTTGTTCTGACTGCAAATAAAGATAGCATTTCTTACAGAAGCAGTGTGGGAACAGGGCCAAGAGAATGGGACATGCTATTTATAAACTTAAAGCTGGCAAGAGAGCTTGGGGTAATTGGGCAAAATTATTTAGCAGAATTGTCTGGTGCCTGCCAGTATAAGTGCTGTGGAACCTTAATGACAGTAGGCATAATTTTAAAAAAATTTCCACAGAAACAAAAATATGGATAGATAGATTTGGCTAATGATAGTAATTTCTTCTGCCATTCAAAAGGTACTTTGCTTTAAACTTTTAAAATTGTTAATAAACACTAGTGAGTTGGGTTTACTGTAATAACTGGTAATTATAGTTCCAATGTTATTTTTTGTTTTTTAATGACAG
Seq C2 exon
GAGTTAGAGGCTGAGAGGGTTAAACTTTTGGAGGATGTTACTTTTAATAAGCGGAAGATGAAAGAACTTGAAGATAACCTCCTCTATAAATTAAGTGCTACAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721:ENST00000359357:74
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127812=AAA_9=FE(26.0=100)
A:
NA
C2:
PF127812=AAA_9=FE(15.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development