HsaINT0050028 @ hg19
Intron Retention
Gene
ENSG00000124721 | DNAH8
Description
dynein, axonemal, heavy chain 8 [Source:HGNC Symbol;Acc:2952]
Coordinates
chr6:38913243-38917346:+
Coord C1 exon
chr6:38913243-38913364
Coord A exon
chr6:38913365-38917227
Coord C2 exon
chr6:38917228-38917346
Length
3863 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATA
5' ss Score
8.55
3' ss Seq
AATTGGCTTGCTTCTTTTAGATA
3' ss Score
7.3
Exon sequences
Seq C1 exon
GGGGAGCAGCTCTGGACCTGAAAGCCTGTCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGTGGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAACCAG
Seq A exon
GTAATACAATAAAGGGCTGGTTGAAAGTGCAGATCTGCAAACCCAAACATACCTGGGCCGCTTAAACTGGGGCTTCCTGGCAGCAATTCCTTCACCCAAAAAAGTCAACCCAATAGTTTGGATTTGAGGCTCTGTGGCTGTCTGGGAGAGATCTTGGACAGATGGACCTCAGGGTTAACCTCTTCATAGTTGCAGGCAACTATGTTTTCCTCCTGTGTGGTGGGCATGGGTCATTTTTGTATGCCTGTTAGAGTTGCTGCTGGAATCAGAACCAGTAGATGGACCCTTTTATTGTAGACGACTCATGCTTTTACACTTTAACTTCTGCCTATGATTAAGTGATTTGTACAGATTTGAATGTGAGTCAAATTAAGAGGTTGAGGTCCCTCTAAAAAATTAATTATTTTAGTGGTGAAATATAATGGTGAAAATGGAGAAATAGGTACCGATTTGCTTGTTGTTTTTTTCTTATTTGAAAATGTACATTGATTACTGTGGATTAATTGTTGAGTCAATTGTTACTGGAAAACAATCATGAGACTCAGAATAAAGATAGCTGTTTCTTACTGGGTTCTGTTGGCTGCAACTGCCTGTCACTAATGGAGCCTGCAGTTTCCCAGTGTCAGATGCCAATAATCATCTCTTTTCTATGGCTGCTAGTGACTGACAGATGGGGCCATAGGTAGACTGCAGGTTGTCAGAGCCTCATGCTGTAATCACCAATCCCCTGCCCAACATACTGTGTTAGCTGCCTCTGTTTGTTTAGTGGCATTTCTGAAACATTGTGTAGACTCTACCTATTCAGCCTGGTTGGGTCTGAGTCAATTGGATAAACTCTCTGGGTTCCATCTGTGGATAGACAGTGAGCTTTGTTTTGTAGTACAACCACAGATGAGTCCTCCAAGCCCAAACAAATGCTTGGAAAAAGAAAGTGATCTTGGGCTGGGCCCGATGGTTCACGCCTGTAATCCCAGCACTTTAGGAGGCTGAGCCAGGTGGATCACGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATAGTGAAACCCCGACTCTACTAAAAATACAAAATATTAGCTGGGTGTGGTGGCGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTAAAACTGGGAAGCGGGGGTTGCAGTGAGCCGAAATTGCACCGTTGCACTCCAGCCTGGGTGACAGTGTGAGACTCTGTCTTGGGGGAAAAAAAAAGAAAAGAAAGTGATCTCGGTCTGATCAGAGATTGGGTAAGGGAGATAGTCAAGAACCACTGGAAAAATCACTTGAAGCCCACGCCCTCTAATGATGGTTTATATTGATACAAGGATATTTATTATTGTTTGCCTCTGCCAACTAGGTTTTAACTACTCATGAGGTAGAATATAGTAGCTATTACTGCTTACTATGGGATAGGTACTTTGCAACAATAACCCTGCCACAGAAGGGCAGAGTTATTGACCCTAATTTATAGATGAGATAACAGAGATTCAAAGAGTTAGTTAAGTACTTGCCCAAGAGCCCATTGCCAATAAGTGGCAAAGCTCATGCTCTTCCCATGCCATCATGAGTTATTTCTCTCCCACTCCTCTTACACCACCGATTGGGCCAGAAGTGGGGTGAGGGGCAGTTCTCAGGAAGGTTGCAAAAGTTCAGCGGAGACCTGCAGTCAGGTGGCCATCAGTCTGGCCTGCCTGTGGGAAGGAAGGGAGGAAGCAGAAGATCAATCTCCCAGCTGAGTGGATGTCAGGAACTGAAATATAATAGAGCAGCTGCCCTGACCTTGGCATCCCAGGCCAAGGGTCAGGAAAAGGAATGAGAAATGGAGATGGACATCCAGAGGCTGGAAGTCATCTTATCACCTATCATGGCTGCAGCTCACTTTGAAGCTCTACTGTGGTCAAGTCAAAATTAGCAGGTGGAAAGTCAGTAGGTGAAGAATAGTCATCCGCTTTCTTCCTGTGCCTCAGCTGCAGATGTGGAGGAGGCCTGTGGGGGACACTGTGGGCAGGGGCAAGGTAGGGCTCGCAACACCCAGGCCCTGGCATGCAGGCATCTTCTTTGAGGGCAGCCAACCAGAGAGAGCTGCTGCAATCTTCAGGAGATAGATGGCAGTTGTGAAACATTTCAGAAATCCTCTTCTTTTTTTTTTTTCTTGAGATGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAATGGCGCAATCTCAGCTCACTGCAACCTCCAGCTCCTGGGTTGAAACAATTCTTCTGTCTCAGTCTCCTGAGTAGCTAGGATTACAGATACACGCTGCCACGCCCAGCTAATTTTTTGTATTTTAGTAGGGACGGAGTTCCACCGTGTTGCCCAAGCTGGTCGCGAACTCCTGAGCTCAGGCACTCTGCCCGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCAGGCCAGAAATCCCCTTCATCTTTTAGTGCCCCAGGGACAAAGTGGGAGCAACTGAGTTGCAGAATAACTGTTCTGTTATTAATTTATACTCTATCTGTATCCTGTATGATGAATTGTTCACACCACAGATATGAGACTTTGGACAGTTATTTAACCTCTCTATGCCTCAATAAAAAGTAGGGGTCATAGAGGAAAAAGTGTAATCCTCAGGTCTGGCATAGGGCATCTGCTATGTGAGCCTTTGCTATTTGCTATTACTGCTTACTGTGGCTTTTTTATTTTAATTTTAATTTTTTTATTTTTTTGTTTTTGAGGGGGAGTTTCGCTCTTGTTGCCCAGAGCTGGAGTGCAATGGCACAATCTTGGCTCACAGCAACATCTGCCTCCTCGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCCACCACGCCCGGCTAATTTTTTTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTTACAGGCATGAGCCACTGTGTACTGTGGCTTTTTTAAAAGCACACTTACAAACACCGTCTAAATAACCCAGCCTGATTGTTGCTGAAGAGCAGGGATAGGCTCAATAATCTATAGTTTTCGTACTTAGTCTTGATGGAACTTGGGCGTCAGTGAGCACCTTTTAATGCCTCTGAAAACCTGAAGTCCTTTTCATGCTTCTGAACAATATTTAAGACCAGCTGTTGGAGAGACTCCTTTCGTTATTAGGCTTTAGGTCTCAAGGTGGGGGATCACTAGGAAAATAAAAGTTTTGATTTTGTCATCTATCATTATTTTTAAGTAGAGATCAACATTTAGAGGTTGGGTTATCAGAATGGTCTGTCAGTGGTTCTCAACTGAGGGTAATCTACCCACCCCCAGGGGCATTTGGCTGTGTCTGGAGACATTTTTGATTGTTAGGACCCGGGTGGAGGGTGCTACTGGCATCTAGTGGATAGGGACGCTGCTAAACATCCTACAATGCCCAGGACAGCACCCCCCACAAAAAAAATTCAGATCCAAATGACAGTAATACCAAGCTTGAGAAACCTTGATTTGTGTTTCTTCTGGCCCAATCATTTGGTGCAGTTGACACACGATCCTAATTGTAGCGAATAATGTAGAAAAATAATGGAAGAACTGGAAGGGAATAGTAATATCCAAGTTATTCAAGTCATTGATCCTGAAGAAAGGTTTAAACTGTGCTGTTATGCTTGAAAAATTATCTGCCTGTAAAGAATGACCCTCTCAGGTGATTCAGAATCCTTTGTAATATATTCCACTTACATATAGTTCTGTGGCTTGCTAATTGGCTTGCTTCTTTTAG
Seq C2 exon
ATATCTCGTAATGAGAAGGGGTGGAAAAGCTGGTTTGATAAAGATGCTCCAGAGGAGGAAATTATCCCTGATGGATATAATGATTCACTAGATACCTGCCATAAACTTTTACTTATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721-DNAH8:NM_001371:78
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=PU(20.2=82.9)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(23.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)