HsaINT0050028 @ hg38
Intron Retention
Gene
ENSG00000124721 | DNAH8
Description
dynein axonemal heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:2952]
Coordinates
chr6:38945467-38949570:+
Coord C1 exon
chr6:38945467-38945588
Coord A exon
chr6:38945589-38949451
Coord C2 exon
chr6:38949452-38949570
Length
3863 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATA
5' ss Score
8.55
3' ss Seq
AATTGGCTTGCTTCTTTTAGATA
3' ss Score
7.3
Exon sequences
Seq C1 exon
GGGGAGCAGCTCTGGACCTGAAAGCCTGTCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGTGGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAACCAG
Seq A exon
GTAATACAATAAAGGGCTGGTTGAAAGTGCAGATCTGCAAACCCAAACATACCTGGGCCGCTTAAACTGGGGCTTCCTGGCAGCAATTCCTTCACCCAAAAAAGTCAACCCAATAGTTTGGATTTGAGGCTCTGTGGCTGTCTGGGAGAGATCTTGGACAGATGGACCTCAGGGTTAACCTCTTCATAGTTGCAGGCAACTATGTTTTCCTCCTGTGTGGTGGGCATGGGTCATTTTTGTATGCCTGTTAGAGTTGCTGCTGGAATCAGAACCAGTAGATGGACCCTTTTATTGTAGACGACTCATGCTTTTACACTTTAACTTCTGCCTATGATTAAGTGATTTGTACAGATTTGAATGTGAGTCAAATTAAGAGGTTGAGGTCCCTCTAAAAAATTAATTATTTTAGTGGTGAAATATAATGGTGAAAATGGAGAAATAGGTACCGATTTGCTTGTTGTTTTTTTCTTATTTGAAAATGTACATTGATTACTGTGGATTAATTGTTGAGTCAATTGTTACTGGAAAACAATCATGAGACTCAGAATAAAGATAGCTGTTTCTTACTGGGTTCTGTTGGCTGCAACTGCCTGTCACTAATGGAGCCTGCAGTTTCCCAGTGTCAGATGCCAATAATCATCTCTTTTCTATGGCTGCTAGTGACTGACAGATGGGGCCATAGGTAGACTGCAGGTTGTCAGAGCCTCATGCTGTAATCACCAATCCCCTGCCCAACATACTGTGTTAGCTGCCTCTGTTTGTTTAGTGGCATTTCTGAAACATTGTGTAGACTCTACCTATTCAGCCTGGTTGGGTCTGAGTCAATTGGATAAACTCTCTGGGTTCCATCTGTGGATAGACAGTGAGCTTTGTTTTGTAGTACAACCACAGATGAGTCCTCCAAGCCCAAACAAATGCTTGGAAAAAGAAAGTGATCTTGGGCTGGGCCCGATGGTTCACGCCTGTAATCCCAGCACTTTAGGAGGCTGAGCCAGGTGGATCACGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATAGTGAAACCCCGACTCTACTAAAAATACAAAATATTAGCTGGGTGTGGTGGCGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTAAAACTGGGAAGCGGGGGTTGCAGTGAGCCGAAATTGCACCGTTGCACTCCAGCCTGGGTGACAGTGTGAGACTCTGTCTTGGGGGAAAAAAAAAGAAAAGAAAGTGATCTCGGTCTGATCAGAGATTGGGTAAGGGAGATAGTCAAGAACCACTGGAAAAATCACTTGAAGCCCACGCCCTCTAATGATGGTTTATATTGATACAAGGATATTTATTATTGTTTGCCTCTGCCAACTAGGTTTTAACTACTCATGAGGTAGAATATAGTAGCTATTACTGCTTACTATGGGATAGGTACTTTGCAACAATAACCCTGCCACAGAAGGGCAGAGTTATTGACCCTAATTTATAGATGAGATAACAGAGATTCAAAGAGTTAGTTAAGTACTTGCCCAAGAGCCCATTGCCAATAAGTGGCAAAGCTCATGCTCTTCCCATGCCATCATGAGTTATTTCTCTCCCACTCCTCTTACACCACCGATTGGGCCAGAAGTGGGGTGAGGGGCAGTTCTCAGGAAGGTTGCAAAAGTTCAGCGGAGACCTGCAGTCAGGTGGCCATCAGTCTGGCCTGCCTGTGGGAAGGAAGGGAGGAAGCAGAAGATCAATCTCCCAGCTGAGTGGATGTCAGGAACTGAAATATAATAGAGCAGCTGCCCTGACCTTGGCATCCCAGGCCAAGGGTCAGGAAAAGGAATGAGAAATGGAGATGGACATCCAGAGGCTGGAAGTCATCTTATCACCTATCATGGCTGCAGCTCACTTTGAAGCTCTACTGTGGTCAAGTCAAAATTAGCAGGTGGAAAGTCAGTAGGTGAAGAATAGTCATCCGCTTTCTTCCTGTGCCTCAGCTGCAGATGTGGAGGAGGCCTGTGGGGGACACTGTGGGCAGGGGCAAGGTAGGGCTCGCAACACCCAGGCCCTGGCATGCAGGCATCTTCTTTGAGGGCAGCCAACCAGAGAGAGCTGCTGCAATCTTCAGGAGATAGATGGCAGTTGTGAAACATTTCAGAAATCCTCTTCTTTTTTTTTTTTCTTGAGATGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAATGGCGCAATCTCAGCTCACTGCAACCTCCAGCTCCTGGGTTGAAACAATTCTTCTGTCTCAGTCTCCTGAGTAGCTAGGATTACAGATACACGCTGCCACGCCCAGCTAATTTTTTGTATTTTAGTAGGGACGGAGTTCCACCGTGTTGCCCAAGCTGGTCGCGAACTCCTGAGCTCAGGCACTCTGCCCGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCAGGCCAGAAATCCCCTTCATCTTTTAGTGCCCCAGGGACAAAGTGGGAGCAACTGAGTTGCAGAATAACTGTTCTGTTATTAATTTATACTCTATCTGTATCCTGTATGATGAATTGTTCACACCACAGATATGAGACTTTGGACAGTTATTTAACCTCTCTATGCCTCAATAAAAAGTAGGGGTCATAGAGGAAAAAGTGTAATCCTCAGGTCTGGCATAGGGCATCTGCTATGTGAGCCTTTGCTATTTGCTATTACTGCTTACTGTGGCTTTTTTATTTTAATTTTAATTTTTTTATTTTTTTGTTTTTGAGGGGGAGTTTCGCTCTTGTTGCCCAGAGCTGGAGTGCAATGGCACAATCTTGGCTCACAGCAACATCTGCCTCCTCGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCCACCACGCCCGGCTAATTTTTTTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTTACAGGCATGAGCCACTGTGTACTGTGGCTTTTTTAAAAGCACACTTACAAACACCGTCTAAATAACCCAGCCTGATTGTTGCTGAAGAGCAGGGATAGGCTCAATAATCTATAGTTTTCGTACTTAGTCTTGATGGAACTTGGGCGTCAGTGAGCACCTTTTAATGCCTCTGAAAACCTGAAGTCCTTTTCATGCTTCTGAACAATATTTAAGACCAGCTGTTGGAGAGACTCCTTTCGTTATTAGGCTTTAGGTCTCAAGGTGGGGGATCACTAGGAAAATAAAAGTTTTGATTTTGTCATCTATCATTATTTTTAAGTAGAGATCAACATTTAGAGGTTGGGTTATCAGAATGGTCTGTCAGTGGTTCTCAACTGAGGGTAATCTACCCACCCCCAGGGGCATTTGGCTGTGTCTGGAGACATTTTTGATTGTTAGGACCCGGGTGGAGGGTGCTACTGGCATCTAGTGGATAGGGACGCTGCTAAACATCCTACAATGCCCAGGACAGCACCCCCCACAAAAAAAATTCAGATCCAAATGACAGTAATACCAAGCTTGAGAAACCTTGATTTGTGTTTCTTCTGGCCCAATCATTTGGTGCAGTTGACACACGATCCTAATTGTAGCGAATAATGTAGAAAAATAATGGAAGAACTGGAAGGGAATAGTAATATCCAAGTTATTCAAGTCATTGATCCTGAAGAAAGGTTTAAACTGTGCTGTTATGCTTGAAAAATTATCTGCCTGTAAAGAATGACCCTCTCAGGTGATTCAGAATCCTTTGTAATATATTCCACTTACATATAGTTCTGTGGCTTGCTAATTGGCTTGCTTCTTTTAG
Seq C2 exon
ATATCTCGTAATGAGAAGGGGTGGAAAAGCTGGTTTGATAAAGATGCTCCAGAGGAGGAAATTATCCCTGATGGATATAATGATTCACTAGATACCTGCCATAAACTTTTACTTATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721:ENST00000359357:78
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=PU(20.2=82.9)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(23.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development