HsaINT0050689 @ hg19
Intron Retention
Gene
ENSG00000079805 | DNM2
Description
dynamin 2 [Source:HGNC Symbol;Acc:2974]
Coordinates
chr19:10940803-10942586:+
Coord C1 exon
chr19:10940803-10941054
Coord A exon
chr19:10941055-10941653
Coord C2 exon
chr19:10941654-10942586
Length
599 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
TGTCTTTATTCTCTTTGCAGCAG
3' ss Score
10.23
Exon sequences
Seq C1 exon
CCCCACTCCACAGCGCCGACCGGTGTCCAGCATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCGTGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTGTTTGCCAACAGTGACCTCTTCCCAGCCCCGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCAGGAGTGCCCAG
Seq A exon
GTAAGGCCAACCCCCTGCCCTCCACCCCAACTGCCTGCACCCTGGGGTCTCTCCTCCTGTCTCACTTCCTCCCAGTGAGCTCTCACTACGTGCCCAGCTGCTGGAGTGGAGGAATCGTCCTCATCCCTATTTGGCTTGCGAGGAAACAGGCCCAGAGAGGCCAAGAGGCTTGTTCAGTGTCACAGAGTAGCGGAGCCCTGGTGACTCCGGGGCTCCCAGCTTGCCCTCTGCCTACTGGGGTGTGCCACCAGGCAGCTGGGGAACCCTCACACTGGGCACCTCCTCCCACTGTTTACCTTCTTCTCCTTCCTGCTCCTGCCTGCCTCAACCTACCGTGGGCCAGGCTTTATTCTCCCCACTTCTCCGGTGGGGAAGCTGAGGCCCAGGGAGGGCAGGGGGCTCACTGAGGGTCAAACAGCAGGCGAGTTGATGCCTAGGTTTGGCACTCCTGCCCGACACCCTGGTGGCTTGCGGAGGTCAGCCTGGGAACACCCTGGGGTGGTGTGTGGGTGGGGGCTGGGTCCTCAACCCAGGCCTGCCTCTTGCTCCCGGCCTCACTGCCGTCTCCCCCTCCCCACCTGTCTTTATTCTCTTTGCAG
Seq C2 exon
CAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCTCGGGGGGGCCTCACGCACCCGCGGCGCAGGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGGCTCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCCGGCCCCTGTGCCTGGCTGGACACCGCACTGCGCAAAGGGGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGATGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAATGAGGGGTCCAGCCTGGGGGGGACTCTACCAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAGTGCGGGCACCAAGGGCGCCTACATCCCCAGGCCTTGCTGGGGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCCCCAGCGGCAAGCCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCTGAGGTGTACATAGTCCTTCCCGGCCATATTAACCACACAGCCTGAGCCTGGCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCGGAGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCCTGGGTCCCCCAGGGTGGCTGGGCTTGGGCTATGTGGGTGGTGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCTGATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCACCCACTCCTCGCTCAGTTTGACCACTGTAAGTGCCTGCACTCTGTATTCTATTAATAAACTAAAATAAAGGGAAGACGCTGCTGGTGGCTGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079805-DNM2:NM_004945:19
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATCTCGGCCAGTTCGGATC
R:
ATCCCCCAAAGTGCAACACC
Band lengths:
358-957
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)