HsaINT0051454 @ hg19
Intron Retention
Gene
ENSG00000115325 | DOK1
Description
docking protein 1, 62kDa (downstream of tyrosine kinase 1) [Source:HGNC Symbol;Acc:2990]
Coordinates
chr2:74783021-74784678:+
Coord C1 exon
chr2:74783021-74783205
Coord A exon
chr2:74783206-74783434
Coord C2 exon
chr2:74783435-74784678
Length
229 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCAG
5' ss Score
3.97
3' ss Seq
TCCCCCTCTACCCTCCTTAGGTC
3' ss Score
10.43
Exon sequences
Seq C1 exon
GATCCCAATTCTGGGTAACGGTGCAGAGGACTGAGGCCGCCGAGCGCTGTGGCCTGCATGGCTCCTACGTGCTGAGGGTGGAGGCTGAAAGGCTGACTCTCCTGACCGTGGGGGCCCAGAGTCAGATACTGGAGCCACTCCTGTCCTGGCCCTACACTCTGTTGCGTCGCTATGGCCGGGACAAG
Seq A exon
GTGCAGGGGCTGTCCGGGAGGGCTTCCTGGGTTGGGCAGCTGTGGGAGGGGTGGGGCAGGACAGAAAGTGGGAAGCTCTGACCTTTGGATCCCCCTTTCTTGCCTACCCGGTGACCCCGCGTCTGTTCGCAGGTGGTCTCTTCTTTGTAGATACCCTAACTAGTGCAGGCGTGTGACTCACTTCCTCTGATGGCTCCTGGTAATGTGTTTCCCCCTCTACCCTCCTTAG
Seq C2 exon
GTCATGTTCTCTTTCGAGGCCGGCCGCCGCTGCCCCTCAGGCCCTGGAACCTTCACCTTCCAGACGGCACAGGGAAATGACATCTTCCAGGCAGTTGAGACTGCCATCCACCGGCAGAAGGCCCAGGGAAAGGCCGGACAGGGGCACGATGTTCTCAGAGCTGACTCCCATGAAGGGGAGGTGGCAGAGGGGAAGTTGCCTTCCCCACCTGGCCCCCAAGAGCTCCTCGACAGTCCCCCAGCCCTGTATGCTGAGCCCTTAGACTCCCTGCGCATTGCTCCATGCCCTTCCCAGGACTCCCTATACTCAGACCCCTTGGACAGCACGTCTGCTCAGGCAGGAGAGGGAGTACAACGGAAGAAACCTCTCTATTGGGACTTGTATGAGCATGCGCAGCAGCAGTTGCTGAAGGCCAAGCTGACAGACCCCAAAGAGGATCCCATCTATGATGAACCTGAGGGCCTGGCCCCAGTCCCTCCCCAGGGCCTTTATGATCTGCCTCGGGAGCCCAAGGATGCATGGTGGTGCCAAGCTCGGGTGAAGGAGGAGGGCTATGAGCTCCCCTACAACCCTGCCACTGATGACTACGCTGTGCCACCCCCTCGGAGCACAAAGCCCCTCCTTGCTCCCAAGCCCCAGGGCCCAGCCTTCCCTGAACCTGGTACTGCAACTGGCAGTGGCATCAAAAGCCACAACTCAGCCCTGTACAGCCAGGTCCAGAAGAGCGGGGCCTCAGGGAGCTGGGACTGTGGGCTCTCTAGAGTAGGGACTGACAAGACTGGGGTCAAGTCAGAGGGCTCTACCTGAGAAGGACGGCAAGGCTGAGGTGGCTAAGGGGGACCATGGGGAGGTGGCACTAGGGATCAAAGAAGATGGTTAGAACCAGCAGAAGCCAGAGGGTGGGAGGGGCCATGCTGTGTGAGACCAGGGGACCAGAGGGATGGGAGAGTCAAGGGAAGGACAATCCCAGGAAGTCCTAAGAAGTGGGGCAGATGGCAGGGCTGAGGATGGGCTCTGCATCCCCCAAAGCCATCCCTTCCCTACTTCCCCAAATGAAGGGACGGCTGTGGGACCAGGTCTGTGGAAAGTGGTGCATGGTCAGAATGGGTGCAGTTTGAGGGGCCTGTGTGGAGGCCTCAGGGAGATGTTGGACTGTGCCTGGATCCTTACTCCTGCATTGTTCTTTGCCAGAGACCTATTTAAAAATTTTAAAATTCTCATTAAAGTCAGCTTGGGTTTAAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115325-DOK1:NM_001197260:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.010 A=NA C2=0.660
Domain overlap (PFAM):
C1:
PF0217412=IRS=FE(58.7=100)
A:
NA
C2:
PF0217412=IRS=PD(38.5=14.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACTCTGTTGCGTCGCTATG
R:
GGGAGTCTAAGGGCTCAGCAT
Band lengths:
300-529
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)