HsaINT0051454 @ hg38
Intron Retention
Gene
ENSG00000115325 | DOK1
Description
docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990]
Coordinates
chr2:74555894-74557554:+
Coord C1 exon
chr2:74555894-74556078
Coord A exon
chr2:74556079-74556307
Coord C2 exon
chr2:74556308-74557554
Length
229 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCAG
5' ss Score
3.97
3' ss Seq
TCCCCCTCTACCCTCCTTAGGTC
3' ss Score
10.43
Exon sequences
Seq C1 exon
GATCCCAATTCTGGGTAACGGTGCAGAGGACTGAGGCCGCCGAGCGCTGTGGCCTGCATGGCTCCTACGTGCTGAGGGTGGAGGCTGAAAGGCTGACTCTCCTGACCGTGGGGGCCCAGAGTCAGATACTGGAGCCACTCCTGTCCTGGCCCTACACTCTGTTGCGTCGCTATGGCCGGGACAAG
Seq A exon
GTGCAGGGGCTGTCCGGGAGGGCTTCCTGGGTTGGGCAGCTGTGGGAGGGGTGGGGCAGGACAGAAAGTGGGAAGCTCTGACCTTTGGATCCCCCTTTCTTGCCTACCCGGTGACCCCGCGTCTGTTCGCAGGTGGTCTCTTCTTTGTAGATACCCTAACTAGTGCAGGCGTGTGACTCACTTCCTCTGATGGCTCCTGGTAATGTGTTTCCCCCTCTACCCTCCTTAG
Seq C2 exon
GTCATGTTCTCTTTCGAGGCCGGCCGCCGCTGCCCCTCAGGCCCTGGAACCTTCACCTTCCAGACGGCACAGGGAAATGACATCTTCCAGGCAGTTGAGACTGCCATCCACCGGCAGAAGGCCCAGGGAAAGGCCGGACAGGGGCACGATGTTCTCAGAGCTGACTCCCATGAAGGGGAGGTGGCAGAGGGGAAGTTGCCTTCCCCACCTGGCCCCCAAGAGCTCCTCGACAGTCCCCCAGCCCTGTATGCTGAGCCCTTAGACTCCCTGCGCATTGCTCCATGCCCTTCCCAGGACTCCCTATACTCAGACCCCTTGGACAGCACGTCTGCTCAGGCAGGAGAGGGAGTACAACGGAAGAAACCTCTCTATTGGGACTTGTATGAGCATGCGCAGCAGCAGTTGCTGAAGGCCAAGCTGACAGACCCCAAAGAGGATCCCATCTATGATGAACCTGAGGGCCTGGCCCCAGTCCCTCCCCAGGGCCTTTATGATCTGCCTCGGGAGCCCAAGGATGCATGGTGGTGCCAAGCTCGGGTGAAGGAGGAGGGCTATGAGCTCCCCTACAACCCTGCCACTGATGACTACGCTGTGCCACCCCCTCGGAGCACAAAGCCCCTCCTTGCTCCCAAGCCCCAGGGCCCAGCCTTCCCTGAACCTGGTACTGCAACTGGCAGTGGCATCAAAAGCCACAACTCAGCCCTGTACAGCCAGGTCCAGAAGAGCGGGGCCTCAGGGAGCTGGGACTGTGGGCTCTCTAGAGTAGGGACTGACAAGACTGGGGTCAAGTCAGAGGGCTCTACCTGAGAAGGACGGCAAGGCTGAGGTGGCTAAGGGGGACCATGGGGAGGTGGCACTAGGGATCAAAGAAGATGGTTAGAACCAGCAGAAGCCAGAGGGTGGGAGGGGCCATGCTGTGTGAGACCAGGGGACCAGAGGGATGGGAGAGTCAAGGGAAGGACAATCCCAGGAAGTCCTAAGAAGTGGGGCAGATGGCAGGGCTGAGGATGGGCTCTGCATCCCCCAAAGCCATCCCTTCCCTACTTCCCCAAATGAAGGGACGGCTGTGGGACCAGGTCTGTGGAAAGTGGTGCATGGTCAGAATGGGTGCAGTTTGAGGGGCCTGTGTGGAGGCCTCAGGGAGATGTTGGACTGTGCCTGGATCCTTACTCCTGCATTGTTCTTTGCCAGAGACCTATTTAAAAATTTTAAAATTCTCATTAAAGTCAGCTTGGGTTTAAGAAGTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115325:ENST00000233668:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.015 A=NA C2=0.685
Domain overlap (PFAM):
C1:
PF0217412=IRS=FE(58.7=100)
A:
NA
C2:
PF0217412=IRS=PD(38.5=14.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACTCTGTTGCGTCGCTATG
R:
GGGAGTCTAAGGGCTCAGCAT
Band lengths:
300-529
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development