HsaINT0051457 @ hg38
Intron Retention
Gene
ENSG00000147443 | DOK2
Description
docking protein 2 [Source:HGNC Symbol;Acc:HGNC:2991]
Coordinates
chr8:21911901-21912510:-
Coord C1 exon
chr8:21912229-21912510
Coord A exon
chr8:21911989-21912228
Coord C2 exon
chr8:21911901-21911988
Length
240 bp
Sequences
Splice sites
5' ss Seq
CCCGTGAGT
5' ss Score
8.4
3' ss Seq
ACGGGGCGCCTCCTCCCTAGGGG
3' ss Score
7.71
Exon sequences
Seq C1 exon
AAATGGCGCCGCTTCGGCGCCTCACTGTATGGAGGGTCGGACTGCGCCTTGGCCCGGCTGGAGCTGCAGGAGGGCCCGGAGAAGCCTCGTCGGTGTGAGGCTGCCCGGAAGGTCATCCGCCTCAGTGACTGCCTGCGGGTGGCCGAGGCCGGCGGAGAGGCCAGCAGCCCCCGGGACACCAGTGCCTTCTTCCTGGAGACCAAGGAGCGCCTGTACCTCCTGGCGGCCCCTGCAGCGGAGCGCGGCGACTGGGTGCAGGCCATCTGCCTCCTGGCCTTCCCC
Seq A exon
GTGAGTCGCGCGGGGTGCGGAAAGGGCAAGGGGGCGTGCAGGCCGAGGGTGTTAGATACTTCCTGTGGGCAAGTGTTACAGGTGTCAAGGTCAGGGTGATGGGGTGCTTCCTCCATGTGGGGGGACCCGAACCCAGTGTGCAGACAGAGCCAGCAGGTTGAGGTGGCCTGAAAGAAGGCCTGGGCCAGAGGGGGGCCTGGGGATCGGGGAAGGTGATGAGACGGGGCGCCTCCTCCCTAG
Seq C2 exon
GGGCAGAGGAAGGAGCTCTCGGGGCCAGAGGGAAAGCAGAGCCGGCCCTGCATGGAGGAAAATGAATTGTACAGCAGCGCAGTCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000147443:ENST00000276420:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.028 A=NA C2=0.450
Domain overlap (PFAM):
C1:
PF0016924=PH=PD(83.5=96.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGTATGGAGGGTCGGACTG
R:
GCTCTGCTTTCCCTCTGGC
Band lengths:
301-541
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development