HsaINT0056578 @ hg19
Intron Retention
Gene
ENSG00000100393 | EP300
Description
E1A binding protein p300 [Source:HGNC Symbol;Acc:3373]
Coordinates
chr22:41542743-41543950:+
Coord C1 exon
chr22:41542743-41542820
Coord A exon
chr22:41542821-41543840
Coord C2 exon
chr22:41543841-41543950
Length
1020 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAAT
5' ss Score
6.06
3' ss Seq
CATTTTGCTCATATTCACAGGTT
3' ss Score
7.6
Exon sequences
Seq C1 exon
ATGGCCCTCTACCTGACCCAAGTATGATCCGTGGCAGTGTGCCAAACCAGATGATGCCTCGAATAACTCCACAATCTG
Seq A exon
GTAAATAGTGAAAAAAATTTTTTTATTTTAAAAGAATCCCCGGTGTACTGCAAGATAATACTTGCTACCTGAACACCCGCTTTATGCCAACAGCAAGTGTCATGATTACCTGCCCATAGAGGAAGAGGGGGTGAAGAGCAGGTTGGCTGGCAGATCACAGGGCAGGTGACATTAAATGATCAAGTATCCATTAAAAAACAACTGCAGGCTGGGCATGGTGGCTCACGCTTGTAATCCCAGCACTTTGGGAGGCCGAGGCTGGTGTACCACCTGAGGTCAAAGTACGAGACCAGCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAATTAGCCGGTTGTAGTGGCACGGGCCTGTAATCCCATTTACTCTGGAGGCTGAGGCTGGAGAATCACTTGAACCCAGGAGGCGGAGTTTGCAGTGAGGCGAGATCGCGCCACTGGACCCCAGCCTGAGTGACAGCAAGACTTCGTCTCAAAAAAAAAAAAAAAAGCAGATTGTAAAATTTGTAAAATTCAGTTTGGAGATCCTGTTAGTTGATAATGTCTGTTTACTGCTACTGTGAATGAGACAGATTTATTTATACTTAGAAGGTTGAAAGCCAGTTTATTAGTCCTGATAGAATCAGGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCACAAGGTCAGGAGATAGAGACCATCCTGGCTAACACAGTGAAACCCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGTGTGGTGGCGGACGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCCAGGTGGCAGAGCTTGCAGTGAGCGGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGATACAGAATCAGACATAAGAATTCTATCTTTTATTATTCAATTTCACAAAGGCATTCAGATCTAACATTTTGCTCATATTCACAG
Seq C2 exon
GTTTGAATCAATTTGGCCAGATGAGCATGGCCCAGCCCCCTATTGTACCCCGGCAAACCCCTCCTCTTCAGCACCATGGACAGTTGGCTCAACCTGGAGCTCTCAACCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100393-EP300:NM_001429:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.915 A=NA C2=1.000
Domain overlap (PFAM):
C1:
PF139001=GVQW=PD(10.0=66.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCTCTACCTGACCCAAGTA
R:
GGTTGAGAGCTCCAGGTTGAG
Band lengths:
183-1203
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)