HsaINT0056905 @ hg19
Intron Retention
Gene
ENSG00000135999 | EPC2
Description
enhancer of polycomb homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:24543]
Coordinates
chr2:149526720-149528506:+
Coord C1 exon
chr2:149526720-149526809
Coord A exon
chr2:149526810-149528360
Coord C2 exon
chr2:149528361-149528506
Length
1551 bp
Sequences
Splice sites
5' ss Seq
GCTGTAAGA
5' ss Score
4.19
3' ss Seq
TGTTTTTTCTTTCTTTGCAGCCT
3' ss Score
11.71
Exon sequences
Seq C1 exon
GTATTGTCCCCAGTATCAGAACCGGAAGAAGAAAATGATCCTGATGGTCCCTGTGCTTTCAGAAGGCGGGCAGGATGCCAGTATTATGCT
Seq A exon
GTAAGAACTTTTGTGTGTGTGTGGTGTTTTTGTGAACTGGAATTAACAGGTAACCCATGTCAAGATGACTTAGTCTTGATCTAAAAATGGGAAATGCATCAGTACTTTTTATTTAACATCCTTTATGTGGATACTGGTAAAAGATGCTAAAAGGTACTGAGTCCTTTCAAAGGGCGTCGGAATCCTCTTCTTGGAAATTGATAATTCCTCACATTTTAGAAATTTAGGTTCATTTTGGGCTCTAATTATAGCTTCAGCAGCTGTGAAAATTACTCAGTGTGTCATTACTAGAATTAGGTAAACCCAGAATTTGTAAGTTGGTTCTAGAACCTTTGATGGCTGCTAGGTGTTTATTGAAATTTATTGTTATGCAAGCCCATCTTGTGCATACATACCAGTAAGTATCAAACAAAATAATAATTTTGTTTGATACTTCCATAATGGCAATGTTTTGTCTAATAATTGTATTCATAACTTTTTGACACACCTAGAAGTTGCTTTATGCTATGAAGTCGCATTATATCACTCTCCAAGGTTCTCAATGAGATATAATGTAGCATTGTGAGGATGGCTTTGACTTTCTTATATGGCTTGTAGAGATCATTTATCTTGCTATATAATGGTAAGCATACACTGACAGCTTTTTTAGAGTGTGTAAATTTAGGAGAGGTGGAGATTTGTTTACTAGTTATGTTGATGAGAGAAGGGAAAATTCTTAACGAAAGGGGACAGACAGCATGATAAAATGATGAAGGGAATGGGAAGGCAGGGAACAGCTTGTTTGTTTCTTTATATTTATTTATTTACTTATTTATTTCTTTTAGAGACAGGGTCTTGCTCTGTCACCAAGGCTGGAGTGCAATGGTGCAATCATACAGTTCACCGTAACTTCAAACTCCTGGGCTCCAGTAGTCCGCCCACCTCAGCCTCCTGGGATTACAGGCGCATACCACTACATGCTGCTAATTTTTGTAATTTTTGTAGAGATAGGGTCTTGCTACGTTGCCCAGGCTGGTCTTGAACTCCTGGTCTCTAGTGATCCTCCTGTCTTGGCCTCCTAAAGTGCTAGGATTACAGGCATGAACCACTGCATCCTGCTTGGATGTGTGTTTCTTAAAAGTAAAGAGGAAGCTTCAGTTTGACCCCATAGTGTTTGAAGTGCAATTTTTAGTCCAAAAAATATTCTTTCTGGTTTCTCAGTAGGAAGCCTACAAATTACTATGTAATTTCACCATCTCTACTTTGTACACAAATGTTAAAAGCTGCATTATTTTTAACTATATATTCCTTTTTAAGTATAATAGACCCTAAATGAATTTATATTTACAAACTAAATTCAGTTTTGGTAATCTTGGTGAGTGAACTTTTGATTCAATTTTGTAAAATTTAACCTGATTAATAGTCAATGAAGCCCCACTTTTACAGTTTTATATCTAGATTTTAATTGTTCTGCTAATGTTGCAGTTACTTCATGTTTATCATGATCTAACCTGTCTTCATTTCAGATTTACTCCATGAGTTTTTTGTTTTTTGTTTTTTCTTTCTTTGCAG
Seq C2 exon
CCTCGTTTGGACCAAGCTAACCATTCATGTGAAAATTCAGAATTGGCAGATTTGGATAAGTTGAGGTATAGGCATTGCCTTACAACACTTACAGTCCCAAGAAGATGTATAGGATTTGCAAGGAGGCGAATTGGCAGAGGTGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135999-EPC2:NM_015630:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.295 A=NA C2=0.014
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCCCAGTATCAGAACCGGA
R:
CTTCCACCTCTGCCAATTCGC
Band lengths:
231-1782
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)