HsaINT0056905 @ hg38
Intron Retention
Gene
ENSG00000135999 | EPC2
Description
enhancer of polycomb homolog 2 [Source:HGNC Symbol;Acc:HGNC:24543]
Coordinates
chr2:148769151-148770937:+
Coord C1 exon
chr2:148769151-148769240
Coord A exon
chr2:148769241-148770791
Coord C2 exon
chr2:148770792-148770937
Length
1551 bp
Sequences
Splice sites
5' ss Seq
GCTGTAAGA
5' ss Score
4.19
3' ss Seq
TGTTTTTTCTTTCTTTGCAGCCT
3' ss Score
11.71
Exon sequences
Seq C1 exon
GTATTGTCCCCAGTATCAGAACCGGAAGAAGAAAATGATCCTGATGGTCCCTGTGCTTTCAGAAGGCGGGCAGGATGCCAGTATTATGCT
Seq A exon
GTAAGAACTTTTGTGTGTGTGTGGTGTTTTTGTGAACTGGAATTAACAGGTAACCCATGTCAAGATGACTTAGTCTTGATCTAAAAATGGGAAATGCATCAGTACTTTTTATTTAACATCCTTTATGTGGATACTGGTAAAAGATGCTAAAAGGTACTGAGTCCTTTCAAAGGGCGTCGGAATCCTCTTCTTGGAAATTGATAATTCCTCACATTTTAGAAATTTAGGTTCATTTTGGGCTCTAATTATAGCTTCAGCAGCTGTGAAAATTACTCAGTGTGTCATTACTAGAATTAGGTAAACCCAGAATTTGTAAGTTGGTTCTAGAACCTTTGATGGCTGCTAGGTGTTTATTGAAATTTATTGTTATGCAAGCCCATCTTGTGCATACATACCAGTAAGTATCAAACAAAATAATAATTTTGTTTGATACTTCCATAATGGCAATGTTTTGTCTAATAATTGTATTCATAACTTTTTGACACACCTAGAAGTTGCTTTATGCTATGAAGTCGCATTATATCACTCTCCAAGGTTCTCAATGAGATATAATGTAGCATTGTGAGGATGGCTTTGACTTTCTTATATGGCTTGTAGAGATCATTTATCTTGCTATATAATGGTAAGCATACACTGACAGCTTTTTTAGAGTGTGTAAATTTAGGAGAGGTGGAGATTTGTTTACTAGTTATGTTGATGAGAGAAGGGAAAATTCTTAACGAAAGGGGACAGACAGCATGATAAAATGATGAAGGGAATGGGAAGGCAGGGAACAGCTTGTTTGTTTCTTTATATTTATTTATTTACTTATTTATTTCTTTTAGAGACAGGGTCTTGCTCTGTCACCAAGGCTGGAGTGCAATGGTGCAATCATACAGTTCACCGTAACTTCAAACTCCTGGGCTCCAGTAGTCCGCCCACCTCAGCCTCCTGGGATTACAGGCGCATACCACTACATGCTGCTAATTTTTGTAATTTTTGTAGAGATAGGGTCTTGCTACGTTGCCCAGGCTGGTCTTGAACTCCTGGTCTCTAGTGATCCTCCTGTCTTGGCCTCCTAAAGTGCTAGGATTACAGGCATGAACCACTGCATCCTGCTTGGATGTGTGTTTCTTAAAAGTAAAGAGGAAGCTTCAGTTTGACCCCATAGTGTTTGAAGTGCAATTTTTAGTCCAAAAAATATTCTTTCTGGTTTCTCAGTAGGAAGCCTACAAATTACTATGTAATTTCACCATCTCTACTTTGTACACAAATGTTAAAAGCTGCATTATTTTTAACTATATATTCCTTTTTAAGTATAATAGACCCTAAATGAATTTATATTTACAAACTAAATTCAGTTTTGGTAATCTTGGTGAGTGAACTTTTGATTCAATTTTGTAAAATTTAACCTGATTAATAGTCAATGAAGCCCCACTTTTACAGTTTTATATCTAGATTTTAATTGTTCTGCTAATGTTGCAGTTACTTCATGTTTATCATGATCTAACCTGTCTTCATTTCAGATTTACTCCATGAGTTTTTTGTTTTTTGTTTTTTCTTTCTTTGCAG
Seq C2 exon
CCTCGTTTGGACCAAGCTAACCATTCATGTGAAAATTCAGAATTGGCAGATTTGGATAAGTTGAGGTATAGGCATTGCCTTACAACACTTACAGTCCCAAGAAGATGTATAGGATTTGCAAGGAGGCGAATTGGCAGAGGTGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135999:ENST00000258484:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.396 A=NA C2=0.017
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCCCAGTATCAGAACCGGA
R:
CTTCCACCTCTGCCAATTCGC
Band lengths:
231-1782
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development