HsaINT0062646 @ hg38
Intron Retention
Gene
ENSG00000099364 | FBXL19
Description
F-box and leucine rich repeat protein 19 [Source:HGNC Symbol;Acc:HGNC:25300]
Coordinates
chr16:30924575-30925931:+
Coord C1 exon
chr16:30924575-30924768
Coord A exon
chr16:30924769-30925730
Coord C2 exon
chr16:30925731-30925931
Length
962 bp
Sequences
Splice sites
5' ss Seq
GGGGTAAGA
5' ss Score
7.83
3' ss Seq
CTGCCACCATCCACCTACAGCCC
3' ss Score
7.88
Exon sequences
Seq C1 exon
AAACTCATCTCCAGCCCTCCTTCCTATGACCTCTCCACCCTGGGGAACTGGCCCTCCTTCCTAGACCCTGCTTCCCCTTGAAAGCCCCCACCCCCGCCTGCAGTCGCCGCCCTCCAGGCCCCTCCCCTGGAGCGCTGGAGGGCCCCTTAGCCCCATGGATGGGTATGAAAGTCCCCGGAAAGGGGGAATCTGGG
Seq A exon
GTAAGACTGACTGGGAAGAGACCCTCCAGGCTTCTAATTCCACATGGGATCTTGGAGGATCTGGTTTCCATGGGAGGGGGAGCCCAAGGGATTCTAGATGATTAGGGATGAAAGCAGCCCGGGAAGCTGGGGGTCCTAGGACTGAGCCCATCCTCAGTTCTGGGAAGATGTCAGGCTGGATTCTAGAATCCCAAGGAATTTGGGAGATTGCCCAGGTGGACCTGAGGGATCCAAGAGGAGGGTGTCCTGGAGGAGGGAACCCTGTGGGGAACAAGAGGGGCTGAGATCTTGGGCTGAGAAGGGTCTCTGAAGAAGCATCTCCAGGGCTGTCAGAGCTCTGGGGAGTTAGTGGGCAGAGGAGATCGTTAGGGACTTGGGGGCAAGGATCTCGCTGGATCTGGTGAGGATAACTGGGTTGAGGGGAAGAGAGATTGGATGGCTGCTGTGGATGAAAAGGTTGGTGGGGCGGGGGGGAGGAAAAGTCCGGAGCTTCCGTCTAGGAATCTCTGGGTATCTGGGAGGTGAATCTGGGCAGTTTACCCCAGATTGAGGTTGGGGAGAGCCTGGGATATTCTACACTCGGATAACAGGGGAAGAGTTGGGATCTCTCCAAGCTAACACCACGGACAAGGAGTGCCTGGCCTTTCCAAGGAGCTCCGGTGTGGGGATGGCAGAGGAGAGGGCCTCGGTGTCCCCTCCTGCTCCCTGGGCTAGGGAAGGGACCCTGAGGAGGCGGTAGAGGAGCGAGGCCAGGAAGCAGTTCTTGGGCTCCTCTTGAGCTGCTGCAGGGAGACAGGCCTTGAGTAGAGGATTGGCCCCCAGATACACAGAAGGGGGTGACCTCCTTGTCCCCCTGAGGAAGAGGGCAGGCTCTAGCTGCCTGTAGGTGGAGGGACCTGTCAGGGGTCTCCCAGGCCAGGGCCCCAGTGGGCCCATCTGACCCTGCCACCATCCACCTACAG
Seq C2 exon
CCCTCGGCGTTGCTGACGCCCCCAATGTCGTCGAGCAGCCGGGGGCCGGGGGCCGGAGCGCGCCGACGCCGAACCCGCTGCCGCCGCTGCCGGGCCTGTGTGCGAACTGAGTGCGGGGATTGCCACTTCTGCCGAGACATGAAGAAGTTCGGGGGGCCCGGGCGCATGAAGCAGTCGTGCCTGCTCCGGCAGTGCACTGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000099364:ENST00000562319:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.191
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0200815=zf-CXXC=WD(100=79.7),PF0013017=C1_1=PU(0.1=0.0)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTCATCTCCAGCCCTCCTTC
R:
CCCGAACTTCTTCATGTCTCGG
Band lengths:
345-1307
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development