HsaINT0065109 @ hg19
Intron Retention
Gene
ENSG00000184922 | FMNL1
Description
formin-like 1 [Source:HGNC Symbol;Acc:1212]
Coordinates
chr17:43322346-43322783:+
Coord C1 exon
chr17:43322346-43322475
Coord A exon
chr17:43322476-43322619
Coord C2 exon
chr17:43322620-43322783
Length
144 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
3' ss Seq
CTGCCCCATCCCTGGCCCAGTGT
3' ss Score
5.39
Exon sequences
Seq C1 exon
CTGTTGGAGATGAAGTCGACTGATCGCAAGCAGACGCTGCTGCACTACCTGGTGAAGGTCATTGCTGAGAAGTACCCGCAACTCACAGGCTTCCACAGCGACCTGCACTTCCTGGACAAGGCGGGCTCAG
Seq A exon
GTAGGAGACACACAGATCCTTGGGTGTGGGGAGGGGCCGTGGGCTGGGGTAGGTTGGGAGAAAGCTAGGGGGCCACAGTATATAATTGGTGGGAGGGCTGCCTCTCCGATTCACTGACCTGATACTGCCCCATCCCTGGCCCAG
Seq C2 exon
TGTCCCTGGACAGTGTCCTGGCGGACGTGCGCTCCCTGCAGCGAGGCCTAGAGTTGACACAGAGAGAGTTTGTGCGGCAGGATGACTGCATGGTGCTCAAGGAGTTCCTGAGGGCCAACTCGCCCACCATGGACAAGCTGCTGGCAGACAGCAAGACGGCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184922-FMNL1:NM_005892:21
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.055
Domain overlap (PFAM):
C1:
PF0218118=FH2=FE(11.7=100)
A:
NA
C2:
PF0218118=FH2=FE(14.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCTGCACTACCTGGTGAAG
R:
CTGAGCCGTCTTGCTGTCTG
Band lengths:
258-402
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)