HsaINT0065118 @ hg19
Intron Retention
Gene
ENSG00000184922 | FMNL1
Description
formin-like 1 [Source:HGNC Symbol;Acc:1212]
Coordinates
chr17:43311439-43313611:+
Coord C1 exon
chr17:43311439-43311567
Coord A exon
chr17:43311568-43313502
Coord C2 exon
chr17:43313503-43313611
Length
1935 bp
Sequences
Splice sites
5' ss Seq
CAAGTATGT
5' ss Score
7.44
3' ss Seq
CTCCTCCACACCCCGCCCAGGCT
3' ss Score
4.25
Exon sequences
Seq C1 exon
GTATGACATGGAGAGCACAGACAACGGGGCTTCCAACTCAGAGAAAAACAAGCCCCTGGAGCAGTCTGTGGAAGACCTCAGCAAGGGTCCACCCTCCTCCGTGCCCAAAAGCCGCCACCTGACCATCAA
Seq A exon
GTATGTGGGCCACAAAGTGGGGTGGTGGGAGAACAGAGAATTCAGCCCCCACACTGCTGCATCTAGCCAGCCCACCCCGGGCCCTTGGGGTTGGCGAGAGGGGTAGCCATGCATTAGGGGTCCGAGTAAGGGACTCATACAGAGTTTGGGACACCAGTATGTTAAGAAGCCATCAGGGGTGGGGCTGGGTGCTGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGACTGAGGTGGGCAGATCATTTGAGGACATGAGTTTGAGACCAGCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAATACAAAAATTAGCCGGGTGTGGTGGTGCACGCCTGTAATCCTAGCTACTCAGGAAGCTGAGGTGGGAGAATCGCTGGAGCCCAGGGGATGGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTGCAGCCTGGGTGACAGAGTGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGAAAAGAAAAGAAAAAAGAAGCCATCGGGGTGGGCACCTAGAAGTTGGAGTCTGGATGGGTCTGGGATAAGAAGGGAGTTTCTGGGTTGGTGGGACCCCTCTTGTATGCATCTAATCCCCTGTTTTCTCCCATGCGGCCTCCAGGTGTCCCCCTTCTCCCCGGTACGTAGCCATCTAGGGGCAGGTGCATGCCTGGCTGACTCCCTCCCAGGGTGGTGGTGGGTTAGGATGAGGTATTCAACTGATGTCCCTGGGTTCAGTGCTGTGGCTGGGTTCCTCCATCCTAACACGGGCATCTTGCTGGGAGGCAGGAAGCAGGCAGTAGATGGACCCTAGAGCATCTTGTGAATCCCTAGCTTCCTGCTTTGGGTCTAGAGGATTGATTGCATATTAAGCCTCAAACTTTCACAATATGTTATTTGTCCATTCATGCAATTATGCATTCAGCAAACATTTTTTTAACACTTAGTATGTATTAGGTATATGGCAGGTGCCCAGGAGACAGGTCACCCTGCCCTCAGGGGCCCACAGTCTAAGTGGGGGACAATTTAGTGTGACAGGCTGTCATGGAAGTGTGCCTGGGAGCTCTGAGAAGGGAGGTGGCCACCACTTGGGACATCAGGAAGGCTTCCCAGAAAAGGTGACGCTGGAACTGTGTCTTACAGACAGATACAGGCTTTACAGGCAGCCATGGGAACAGGGAAGAGCATTCCAGGCAGAAGGAACAGCATGAACAAAAACTCTGACATATTAGCACAATGACAAGAAAGGGTGATGTGGCAGGAGGGGGTGAAGGCGGGGCCTCCTGGTATTACTGGGAATGTGATAGAATCATCAGAGAGACTGACATGTGGAAGTCCCGGTCGGCAGTTCTGCAACAATGAAAACATCACACATTTGTTGGCGAAGAATAAGGGAGTACAGTCATATAGCACTTACTATGTGCCAGGCACTGTTCTAAGCCTATTCCATAGTCCCAACAACCCTGACAGGAAGCTACTATTATTAGCATTCCTATTCTAGAAGCGAGGAAAGTGAGGGATAGGGAGATTAAGTGACTTATCCAGTAAATGGTGAGCTGGGATGCGCCTGAACCCTGGCAGTGTGAATTCAGATCTGCGTCTTACATTGGAAGATGAGCCCAAGTGGCCATGAGCGCCACCTTGTGGTGATCCTTCCCATGTCTCTTCCTTCTATAGACCCTCACCCTACCAAGTCCCTGGGAAGTGTCTTTGCTTCTGTGTCCCCCCTCCTCCAAGCATGCCAGACCCCAGGTCTAAGGACTGAGGAAGCCTGCCTGCCCTCAGCCAGCCTCTTTGGTTGGGTAGATGGGATGTGGTGCCGTCAGGTTCCAGATGTGCCTCCTCTTACCCCAGAGGCTGAGTGGTGGGGAAACAGGAAGCTGGGGCTCACTCTGACTCCTGCTGCCTCCTCCACACCCCGCCCAG
Seq C2 exon
GCTGACCCCAGCCCACAGCAGGAAGGCCCTGCGGAATTCCCGCATCGTCAGCCAGAAGGACGACGTCCACGTCTGTATTATGTGCCTACGCGCCATCATGAACTACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184922-FMNL1:NM_005892:6
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.795 A=NA C2=0.022
Domain overlap (PFAM):
C1:
PF063718=Drf_GBD=PD(7.5=25.0),PF063718=Drf_GBD=PU(3.8=6.8)
A:
NA
C2:
PF063718=Drf_GBD=PU(45.3=91.9)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTATGACATGGAGAGCACAGACA
R:
CTGGTAGTTCATGATGGCGCG
Band lengths:
238-2173
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)