HsaINT0065142 @ hg19
Intron Retention
Gene
ENSG00000157827 | FMNL2
Description
formin-like 2 [Source:HGNC Symbol;Acc:18267]
Coordinates
chr2:153415254-153417549:+
Coord C1 exon
chr2:153415254-153415337
Coord A exon
chr2:153415338-153417396
Coord C2 exon
chr2:153417397-153417549
Length
2059 bp
Sequences
Splice sites
5' ss Seq
AACGTAAGT
5' ss Score
10.74
3' ss Seq
GCATTTCTCTTTTGTTTTAGTTT
3' ss Score
9.73
Exon sequences
Seq C1 exon
ATGGGTCAGAGAATTTCTGAATGAAGAAAACAAAGGTCTTGATGTTCTAGTGGAATATCTCTCATTTGCACAGTACGCGGTAAC
Seq A exon
GTAAGTAAAACTTGGCTTGCTTGCATTTGAATTTTATGTGGTCACAGCAGATGCTACTCAGTGGTAAAATTATACACCACAGAGAGGGCAGAAACTCAGAAGCAGATGTGCTAGGGCTTAGGGAGGTTTGTTTCTGTTTGGGTAACTAAAAACAAATCACATAATGGTATTAGAAATGCCTTTAAGGCAGAAGTAAAACAGGTGAATAAAAATCACTCTTAAAGGAGCCCTTATTTTCAAAAGTAACGCTTTCTTTAGGGCTTAAGTTACATATATGGAAGAATAGTCTAACAGTTGGTGAAAGAGGTATGTGATAAATCACTAGGCGATGCAAAAGAGTGACTCCCTTTTTCTTTTAAAAATGATGTCTGCATGTATATTTGCATATGCTAGTAAGTGCATAGAAAATGATTGCAGAAACAGATACCAAACGTAGTGGCACTGGAGGGAGAGGTAACAGGAGGCTGTTCCTTTTTCCTTGATATGCATTTGTATTGTTTTGATTTTCTGCCCATAAGCTGAAGGGGAGTAAAAACTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCTGATCAAGTGATTCTCCTGCCTCAGCCTCCTGAGAAGCTGGGATTACAGGCACCCACCACCATGCCCGGCTAATTTTTGTATTTTCAGTAGAGACGGGGTTTCACCATGTTGGGCAAGCTGCTCTCGAACTCCTGACTTCAGATGATCCACCCGCCTCGGCCTCCCCAAAGTGTTGGGATTTCAGGTGTGAGCCACCGCACCCAACCTAGAAGCACTCATTTCTATGTGTGTTTCCTTTTTCTGCTGTGTGAGAGTGAGGATGAGCTGAGAGGAACACACGCTGAATGGCGTGGGAGCTGTAGAGTAGCCTAGCGAGGGCATCAATGCCACGAGTGATTTCAGGATGCCCTCCTCGTCTTACCTTCTCTCATCTCAGTGATTGCTTTCTCTTTTTAGCAGTTAAAATTTTATTAGATTACCCCATTCTAACTCTTTTATGTTCAGTATTACCTCCTGCAGCCAAAGGCATGACAGAATTGTGACCAGTTGCCTCCATGGACTTTGTGCATCTATCTCTGCTATCTGATTAGTCTTTTATAGGTGAAAGTCATCACCAATTTTCAGATGAAGGTTCTAACCAAATATTTTATTTTGGCAGTTATACTTTTATAAAAAGTTACACTTTGATTTCCAATATGTATTATTGTTTTTTCTTCTGCAGTATCCTCTAAGATTTTCCTGAGGATATTAAGTGTAGCTACCTTCTGATTGTTCTACTGTCTGATCAGGTGTTGCTATGGATAGAAACAATTAATACAATTTCTTTTTTTTTTTTTTCTTTTGAGAAAGCACAGTTACTTTGTGAGGGGGGAAATGCATGGAGCACAAAAGCCTGTCTGTTTAAAAACTTTGTTCCTAAAACTATACAAGAGTGAGCAAGTTAACTTGTCATTTATTCTAACATGGTTAACATGAGTAATAACCTCAAAAAATGTCAGAGAAACAACAGTCTTACTTTAAAGAGCACCACACTGGGAGGAGATTCCAAAATCAAAGCAAATCCATAACTTTGCTAGTAATGTATCACATATGCTTGGAAAAGTACACTTGCCAACACACTAGGAGAAAATGCTCAGTGAAAATTGATGGGTAGGAATAAATTAGTATAAGCCTAACATATTGACTTGTTAAAGCAAAATGAAGACAGCTGTAAGATCTTTTCCCCCTTCCATCATACCAATGTTAGTGACTTATATATTAGCAAGCCTTATAAAATAAAATACAAATAATATATCACTATTTAATTTTTGCTGCTCATTGTTCCATTATTCTTTTGCCAGACCCATTATTTGTCATTCTGTATTCTTAAAGCTAACACTGAGCCCATAGAAATTCCATTATATTTCCTTTCCAGTTTTCTTTGTTTACAAAGACTTTCCATACTAAGGTGCAGATGTCTTGTAGGAACAGCAAGTTATACATGTTCGTTTATACATGTGAATGTGAATTTTTCAGTCTTCAATGGCATTTCTCTTTTGTTTTAG
Seq C2 exon
TTTTGACTTTGAAAGTGTGGAGAGTACTGTGGAGAGCTCGGTGGACAAATCAAAGCCCTGGAGTAGGTCCATCGAGGACCTGCACAGAGGGAGCAACCTGCCCTCACCTGTGGGCAACAGTGTCTCCCGCTCTGGAAGACATTCTGCACTGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157827-FMNL2:NM_052905:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.192
Domain overlap (PFAM):
C1:
PF063718=Drf_GBD=FE(20.4=100)
A:
NA
C2:
PF063718=Drf_GBD=PD(8.0=21.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)