HsaINT0065168 @ hg19
Intron Retention
Gene
ENSG00000161791 | FMNL3
Description
formin-like 3 [Source:HGNC Symbol;Acc:23698]
Coordinates
chr12:50050865-50052377:-
Coord C1 exon
chr12:50052225-50052377
Coord A exon
chr12:50050974-50052224
Coord C2 exon
chr12:50050865-50050973
Length
1251 bp
Sequences
Splice sites
5' ss Seq
CCGGTATGT
5' ss Score
9.2
3' ss Seq
TGCCTGGCCCATCTCCCCAGGTA
3' ss Score
9.51
Exon sequences
Seq C1 exon
GTTTGACTTTGAGGGTCTGGAAAGTGGTGACGATGGTGCATTTGACAAACTCCGGTCCTGGAGCAGGTCAATCGAGGACCTGCAGCCACCCAGCGCCCTGTCGGCCCCCTTCACCAACAGCCTCGCTCGCTCTGCGCGCCAGTCTGTGCTCCG
Seq A exon
GTATGTGTGCTTTTGCTCTGCCCACCTGCCTCCCACCCTACCCTTCAGTGCAGGTCTCGGGTTCAGCAGTGAGTGCTCATGCTCCTCCCTCCACTCTTGCTTCCAGGCTCAGCTCTCTTGCCCTCTGCCTGCCAGTCTGTCTCTGGTCTGTCTTCTCTGTCTCCTTGACTCTGCCCAGCGGTCTGTCCTGGGTAAGTACATGGTCTCAGCTGCACTTACCCAACGTGGGGTTCCAGCTCTCCCCATTCCTCACCCCTCTCTGGGGGAGCCCTTCATTCCTCTCACTCTGCCATTCCTCCTGGGTCTCTTGAGCAGGGCACATCTCATACAGGTCCATGGCCTTCACTGGGTGATCCAGCTCCTACTCTCATTCTGTTTCCCTCTAGTTCTTCACTCTGCCCCTTTAGCTGCTTGGAGACCAGCTCCCACCCAACCTGGCTGCCCCTTGCATTCCCTTCACCTCTTCCTTCAGGCCTTTCTCTCTGAGGCTGCCACATGCTCATTTGTCTGCGGTGTCTTAAGAGCCGCCCTGCCTGGAGGTAGGCGGATGGACTGGATGACTTCTCAGAGCCCCTTCCTACTCTGGGAGGCTTTCCTTTGGGTCCCATGGCCCTTTCCTTGGTTTCTGTCTCTCTTGTGGCCATGCTTTCCTCCTAGTCTCCTTTGGGTTGTGTCCCTTGGACACTGTTGATTATTCTTGTCATGGATGAGCAGATACTGTATGTGTCTCCTCCCTTTTCCATGAAACATCACTGAGAGGGTGGAGGGGTGGTGCAAAGCCAGACATAGCCCTGTGGCCCAGCTGAAGCCTTTAGGGGTCAGCTCTGCCTTTTCTGTGATACAGAAGTGGGATGGGAGCCATGACGCTCTTGTCCCACAGATTGTGCAGAAGGTGCAGCAACTGGAAGTGGGTGGAGGGAATGCTCAAATGACTGTGTCTCTGGAGCCATCTCAGGGACTAGGAAGGCCTACACAACTACTATTTGTATTTTGAAGGATCTCTAGGGTTGGGGCACTGGTTATAAAACCGGGATCCTGAATAGTTGCTGACAAAGGCCTGTTTAAGGAGGTGAAAACAGGCTGACCACCCTGCCTCCTGCACCCTGTCCCTCTTGGCTGTTGGTACGAGGTGCTATTCCCTATTTTTTGCCACTGCTAAGGGGCAGCCTGCTGTCCGGGTGATGGTGAGTGTCCCTAGATGCTTCACTGGCAGCCTCAGCTCCCACCTGACTGCCTGGCCCATCTCCCCAG
Seq C2 exon
GTATAGCACTCTCCCTGGGCGCAGGGCCCTGAAGAACTCCCGCCTAGTGAGCCAGAAGGATGACGTCCACGTCTGTATCCTTTGTCTCAGAGCCATCATGAACTATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000161791-FMNL3:NM_175736:6
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF063718=Drf_GBD=PU(42.3=81.1)
Main Inclusion Isoform:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTTGACTTTGAGGGTCTGGA
R:
CTGATAGTTCATGATGGCTCTGAGA
Band lengths:
262-1513
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)