HsaINT0065310 @ hg19
Intron Retention
Gene
ENSG00000187239 | FNBP1
Description
formin binding protein 1 [Source:HGNC Symbol;Acc:17069]
Coordinates
chr9:132671169-132678259:-
Coord C1 exon
chr9:132678245-132678259
Coord A exon
chr9:132671279-132678244
Coord C2 exon
chr9:132671169-132671278
Length
6966 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGC
5' ss Score
8.69
3' ss Seq
ATTTATATTTGTGTCTGCAGGGT
3' ss Score
9.41
Exon sequences
Seq C1 exon
CTTTCTCTCAAGCTG
Seq A exon
GTAAGCACAATTGTTCCATGCATGTCCTGAGTCTAATCAGGTTTTCTGGCGTGTCTTTTATGAATGCTATGCCATGCACAACGTATCTTCAAAGTTAACTTGGTTTGTGTTTCTCTTACGTGTGCTTTTGTTGGTGTTTCCTTATTAGACTTCTTGGATACAAAGGTCCAGAATCTAATAGAGGTGATCTTAATCTTTTCAAGTTGCTAAGAAAATTAACATTTAACTCACGACTTGGTGTTATTCCTGGGGCCTTGAGAGGAGGACAAATGTTAAAGTGTCTATATAAATATTAACGTAAAGGCCGGGCGCAGTGGCTCACGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGTGGATTGCCTGAGCTCAGGAGTTCGAGACCAACCCGGGCAACACGGTGAAACCCCATCTCTACAAAAAACCAAAAAATTAGCCGGGCGTGGCAGCGTGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGAGAACTGCTTGAACCCGGGAGGTGAAGGGTGCAGTGAGCCGAGATTATACCACTGGACTTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCCAAATATATATATATGAACGTAAATATTAAATCTTGGGGGGTGTCTGTTGGATCATTTTGAATAAAAGTAAATTAATAGTTGAAAAATGTTGCTATTAGAGAACCATAGAAGTAGATGAAAAAATCTGGGAGCCTGGAGGAGCTGTGCAGGAATGATCCCAGCCAGCAGCTGCTACCCAGGTTTGAGGCCACCTGTGGGAATGGAAGACTGTGGAATCTTTATGGTGCGACGTAGATATGTTGGTGCCTTGTGCATAGCTGATTCAAGAGGCCACAAGATGATTTCATGGACAGTGAAAAGAGCCTCCTAAGCCTTTTTAGAATTATTCACTCAGTGTTTTGTGTCGTTTCTACTTAATTGTATATGCCTAGTCAACAGTCAAACTAATCATTAAATTTATTAAAAGTAACTAACATAACCTATAACTATACTTCAAATATGTATAATAGTTTCATAGTCTTCTCAAACTCCACAGCTAAGAATATCCTAAAATAATGGACAGTGATCAACTGTGACAGTTCTACTAGGAGTAAGATCAGCACTATAAGCACACTATTGATAACCTAGGATAGTATTTTATGGTGAGATATATATATATATATATATATATATATATATATATAGACATATGTATGTATATACATAATTTTTTCAACATGACTTAGTATTTGGTAATGGACCCAACCTTAAAGAAAAAGAGTATTTTATTAAATTAAATAAACATTTCTTAGGCTGTGAAATAAAATCCTGAGAAGAGTCTTTGATTAAGGTCTCTACATGAAGGAAAGAGATCTAGATACTTAAATGAACTACAAGTTCATCTGCAGTATGAACTTGGGAGAAACTGGATCTATTGACTAGGAGGCCTTCTCAGCTGCCAGGGTTTCCTTATTTCCCTTTATTCATTGTTTGTCTGGGTGCTAGGAGCAAAAGGTAATATTTTTAGGCAGTCTTTCTGTTTGAAATACAAATTATTTTACCAACTTGGTATTGAATTGTTGCTTTATATCATTACCTTGAAGGCAACAAAGAAGTGAAGCGCTGGCTGGGCACGGTGGTTTGTGCCTGGAATCCCAGTGCTTTGGAAGGCTGAGGCAGGAAGATTGCCTGAGCCCAGGAGCTCAAGGTTGCAGTGAGCTATCATTGCGCCACTGCACTCCAGCTTGGGTGACAGAGTGAGACCATGTCTGAAAAAAAAAAAAAAGACAAAAGAAAAAAGATGTGGGACCAGGTGTGGTGGCTCACGCCTGTAATCTCTGCACTTTGGGAGGTGGGGGCAGGCAGATCATTTGCGCCCAGGAGTTCTAGACCAGCCTGAGCAGCATGGTGAAACCTGACTCTACAAACAAATACAAAAATTAGCCAGGCATGGTGGTCTGTGCCTGTGGTCCCAGCTATACTGGAGGCTGAGGCAGAAGGATTGATTGAGCCCAGGAGGTTGAGGCTGCTCCAGCCTTGGGTGATAGAATGAAACCCTGTCTCAAAAAAAAAAACTATAAAACAAAACAAAAAACCCAAAATCTGAAAAAGTAGTATTACACGGAGCTTGTGCTATTTTGGGGTGGGGGGAAGCTGTCAACAAGCAAGGGTTTGATTTTTTTTTCTTTTAGGAGACAGAGTCTCGCTCTGTCCCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCATGCCTCAGCTTCTCGAGTAGCTGGGATTATAGGGGCGCGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGCTGGCCAGGCTAATCTCGAGCTCCTGACCTCAGGTGATCCGCCCACCTCAGCCCCCCACAGTGCTGGGATTACATGCGTGAGCCACCAGGCCCGGCCAGGTTTGATTTTATTAGTACATAGAACAAGCTTCTCTTACAGAACTCCAGCCACTTAAAACATAGGTACATGTGTATGACCCTCTCTTCCCATACCAACTCCTCCTGTTATGGCCTGTCTTTGTTGTTTTCTTATCTATTTATAAGTTATCAGTACAATGTGTTTTACTGATAGATTTCTTTGCACCTGTTTATACACCTGCACAGAGGCTAAAGCTGTTGTCCAGTGTGGTAGCCACTACCATATGTAGCTATTGAGTTTTTTGTTTTTGTTTTTGTTTTGAGATGGAGTCTCGCTCTGTCACTGAGGATGGAGTGCAGTGGCATGATCCTGGCTCACTGCATCCTCCGCCTCCCGGGTTGAAGCGTTTCTCCTGATTCAGCCTCCCGAGTAGCTGGGATTACAGGCAACTGCCATCATGCCTAGCTAATTTTTGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTGACCTCAGGTGATCCGCTCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCCAACCGCTGTTGAGTTTTAATTAATTAAAATTAAATAAATTTTTAAAAATTCAGTTCCACAATTTCACCAGCCACATTTCAAATGCTTCACAGCCACACATGGCTTCTGTGTTGGAAAGAGCGGCCATAGAACATTGCCATCACTGTAGAAAGTTCTGTTGGACTCACAGCACATAGCAAGGCTCAGCACATATTAACGAGGTGAATGTTGACCACTTGCCAGATTTTGTGACTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTTACTCATGTTGTCCAGGCTGGAGTGCGCAGTAGCGCAATCTCAGCTCACCACAACCTCCACCTCCCGGGTTCAAGCGATTTTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGACGGGCGCCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTTTCCATGTTGGTCAGGCTCGTCTCAAACTCCCGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCCAAGATTACAGGCATGAGCTACCGCGCCTGGCCTAGATTTCCTGATTTCTGAAGCAGTGTATCTTAGCATTGTGTTTTGCTGTATTCCAGCTTTTAAAAAATTCTCAGTTCTGGAAAACATGCTCATTTGATAAAACTCAAACCGTTTTTCCTCTGCTGTTCCACTATGACAATCAACAGAGAAGATTTCTGTGACCAAATATGTGGAGGCTTCCGCTATATATCAAGCAGCAGACACTAGCTGGGTGTCCTTTAATTCAATTCCATTCTGATGCTATCTACCTGGAGATAGTGGCTGATCCTGGGGGTTGAGGGCTCAGTCCTGAAGGACTGCCCCCTCCTTCCCACCAGTCGCAAGTCCAGGCTTCCAGGACTTCTGATGGACTAGCTTCAAGTTGGGGTTCCCCTGACCCTCTCTTTGGGTTCAATTAATTTGCAGGAGCAGCTCACAGAACTCAGGGAAACACTTATATTTACTGGTTTGTTTTTGGGTTTTTTTTTTTTTTTTTGAGACAGAATCTCGCCCGTCGCCCAGGCTGGAGTGTAATGGCGTGATCTTGGCTCACCACAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCTCAAGTAGCTGGAACTACAGGCGGGTGCTACCACACTCGGCTAATTTTTTGTGTCTTTAGTCGAGACAGAGTTTCTCTATGTTGGTCAGGCTGGTTTCGAGCTCCTGACCTTTTGATCTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCTGGCCACCACATTTACTGGTTTATTACAAAGGATATTATTAAAAATACAGATGAAGAGATGCTTAGGGCAAGGTGTGGGGGAGGGGGCACAGAGCATCCATGCCCTCCCCGGGCAGCCACTCTCTAAGAATCTCCCCAAAAACCCTGTCCTCTTGGGCCTTTTATGAGACTTCATCAGATAGACATGATTGAAGCATGGACAACCATGTGGAAATGAGATTGGTCAGAAACTGCCTGATCGCATCCTAATAGATCAGGTAGTGACACCCAGCAGGGCCTGTCTGTGCAGATTCTTCTTGGCCTCCCTGTGCAGCCTTCCTTCCTTCAGGGTATGGGGCACGATCCTCATGAAGCCTCTTGAATGAGGATCATATGGCCACAATCAGAATCCTGCCTTGGGCAGGTGAAAGAAGGGCACGTGGAGGTCAGATAGAGAGATTCTGTTTTCTGAGGTCGAAAGTGCTCTGATATTTTAACAAAAGACTGTAGCAAGAGGCCGCGCATGGTGGCTCATTCCTGTAATCCCAGGACGTTGGGAGGCCGAGGTGGGCAGATCGCCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACGTGGTGAAATCCATAATCCAGAATAATCCAGTTTTCAAATAAATATTGTAGCACCATAGTATACGGAAAACAAGTCTTTATTTTTATATTAAAGGTTAGTTTTGCTTCATCTTAGATTTAGAGTCAAACTTCTTTGGTTTGCTATTAGGAATAGTCACTTCCATTCTGGTTTCACTCAACTCTTATCTCACACACATACACACACACACACACACATTAGAGAGTCAGTCAGTGTGTCTGATGGGTGTGTCTTTGAGAACATTAGCTGAAAGGTCTTTGCGTGGCCTTTTGTGGTCAACTATTTGCTGAATCACACACTTCCCAGCACATCACCCTGGCATTTTATCATAATCAGCCTAGGAACCCAGTCATAAGCCCACATGTAAGCTGCTTGGCAAATGCAACTTGCTTCTGGAATTACATTAACTGGGTCTCCTCTTTCTACCCTGCCCCAAGCCTGCCTTGCCCTTGTTTCAAAAGAATTGAGGGTTTAAAGTAAAATCTCTTTTCTAAATGCCCTGGCTTATCCCTGGTTATTTGAAGAAATTTCTCTCTCTCTTTTTTTTTTTTTTTTGTTTTTTTGAGATGGAGTCTCGCATTGTCGCCCAGGCTGGAGTACAGCGGCACGATCTCGGCTCACTACAACCTCCGCTTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTATAGGCGCTCGCCACCACGCCCAGCTAGTTTTTTATATTTTTAGCAGAGACGGTGTTTCACATTGTTGGCCAGGCTGGTCTCAAACTCCTGACCTTATGATCCACCCACCTCGGCCTCCCAAAGTGCTGGAATTACAGGCATGAGCCACCGTGCCCAGCACGAAATTTCTCTCTCTTTATGAACATAGCCTCACTTAAGTAAAAGCACTTGACATCACAATTTAGCCAGAGCTTTCTAACAAGTAAGCATATGTCAAAGCCTGAAACTGTTGATACTTTCTCCTTAAAGCTCATGCACAGTGTAAAGAGAGCAGCTGCTTCTGAAAAGGGAATCAAGATATCAAAATGCAGTTCTTCTGACAGATTAAAAACCGCGGAGATGAGTTTCGTACACTGTGGAAAACTGATTTTGAGGTCAGGGAGGGCATTCTCTCTGAACTCTGAGAGGCTTCCTAAAGGCCTAAAAGAAGTCACTAGGCTGGGCGCGGCGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGAGCAGATCACCTGAAGTCAAGAGTTAGAGACTGTGGAAAATTAGCCGGGCGTGGTGGCACATGCCTGTAGTCCCAGCTACTTAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGTGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAGGAAAAAAAAAAAGTAACTAGACTTTTAGAGGCAGCAGAGGGAGGTGTGCATGGGGTAAGGAGAAGAGATTTTTTTTTTTTAATGTTCTTTTTCACCCACATTCTCTGAGGAATGTGATGTCCCATCTGTCACTTTACAGGGGTGGAGACTTTTGGCCTCAGCCTGTGTGAAGAGACTGGCAGGAATACTCACGCTAGGGAAAAGGCAGCAGCTAGGCGTGCAGTGGTTGATGGGGTTTGTATTAAGGAAACATAAATTTCATTAACACTTCAGTGTTGCCACTGACATTGATGGTAACACTTGGTAGGAAAAGGAAGAAGACTGTCTCAAAATGTGTTTTTCATGGATTCTCCCTAGAGTCAGAAGTATCTCTTACTCTCCTTTACTGTAGCGTTGCTCACTGCTTTTTCTGGGGCATTCTGGCCAGCATCCATGGAACTGGGAATGGTTTATGGGACTTATGCAGTTTGCATGCATTGATTTTTGCATCTCGGCTGGGTGTAGTGGGAAAGAGCTTAATCTATTTCATGAAGCCACATGCAGATGTCTGCACCCCCCATGGCTGCAGGCTTTGCTTTCAGCCTTCTTTCAAGGAAAGCCTGGGGCTTTCTGGTTTCTCATTTATATTTGTGTCTGCAG
Seq C2 exon
GGTGCAACACCGGAGGATTTCAGCAACCTCCCACCTGAACAAAGAAGGAAAAAGCTGCAGCAGAAAGTCGATGAGTTAAATAAAGAAATTCAGAAGGAGATGGATCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187239-FNBP1:NM_015033:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.100 A=NA C2=0.979
Domain overlap (PFAM):
C1:
PF039618=DUF342=FE(3.2=100),PF136541=AAA_32=PU(2.0=60.0)
A:
NA
C2:
PF039618=DUF342=FE(28.8=100),PF136541=AAA_32=FE(24.0=100),PF143891=Lzipper-MIP1=PU(34.9=78.4),PF0396210=Mnd1=PU(28.1=73.0),PF154561=Uds1=PU(37.8=91.9),PF0043516=Spectrin=PU(32.1=70.3),PF0218511=HR1=PU(31.5=62.2)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)