HsaINT0065334 @ hg19
Intron Retention
Gene
ENSG00000137942 | FNBP1L
Description
formin binding protein 1-like [Source:HGNC Symbol;Acc:20851]
Coordinates
chr1:93998479-94000465:+
Coord C1 exon
chr1:93998479-93998625
Coord A exon
chr1:93998626-94000261
Coord C2 exon
chr1:94000262-94000465
Length
1636 bp
Sequences
Splice sites
5' ss Seq
AGAGTAAGT
5' ss Score
9.35
3' ss Seq
ACCTAGTTTCTTTTGTATAGGAC
3' ss Score
6.76
Exon sequences
Seq C1 exon
CAACTACAAGAAATGGACGAACGAAGGACTATTAAACTCAGTGAGTGTTACAGAGGATTTGCTGACTCAGAACGCAAAGTTATTCCCATCATTTCAAAATGTTTGGAAGGAATGATTCTTGCAGCAAAATCAGTTGATGAAAGAAGA
Seq A exon
GTAAGTGCTAAATAATTATCTTTGAATGCATCTGTTTGGTTTAGGTGTGCAGTTTAAGTTAGTGAAATGAGTTGAGAAAGGGATAAAGTAATCTGATGTGTGGTTCTAAATTATATTCTGTAGAAGAATGTCTTGCAATAGATTCCTTTGAGTTCTGAGATTCATTCTACATGCAAAAGTTCTAATTCTTTCTTAAAAAAAAAAAAAAGATTTCTAACTCTCTTCTCCCACTAAGTTTTCAGTTCTTATCAAAGAGTCTAACCTAGGAACTGTGTGTTACAAATTGTGTTATACTATTATATTAGTTTAGTGAAAATTTAGAGAAGTATGTGGTTAGAGTTGCCTTTAGCACTTGAGCTGGATCAAGAAATGTGGGTAGCATATGGAGTGATGACCAATGAGGAGGAGGAAGGAGGGCATTATGTGCAGATGAAACAGCATAGCCCTCCTCCCCTTGAGGATAGGTAATCACATTGTATCTTGATTAAGGACTAGGGTCTTTTATCTCAGTAAATGTTGATTGAGTGATCAAAAAGCATGGTTGGCAGAAACTGAGGAAAGGCAGTGGCAAGAGAAGAGAACTGGTGTTTGCAGGATATCAGATATGTGTCACATATTTTAGTCTTCATGAACCTATCAAGTAGATATTATATTAGTGAGGATCCTTTCTGTTACAGCTAATAGAATTCTCACTTAAATTTAGAAAAGAGGATTTTTGGCTTTCAGCATGGCTGGATACAAGTTTATACAATATCATTACAGCCCTCTTCTCTCTAATTACCCTTTAGCAAATTATTGCTGAGGGTAGCATTACTGACAAAAGTAAGCTATGACTTAAGGATGACTTTTGACTAAATGAAGGGCAAAATGTACTGTTAACAGAAATAGGCAACAAAAGAGAGGTTGTTGTTAGGGGTGGGGAGGAATTTGTAGAGATACTCTGAAAATAATGAGTTTAAGGTATCACTAAAGCATTCAGGTAGAGGTATGTATGTCTAAAAACAATATTTATGTGAGTTTAAAAATTTTAAATACATGGTATTAAACTTTCAAATGTTGTTTGCACTCAGTAGTGTTTATGAGATCTTTTCCCTGTTGCTCTGTTAACATTCCACAGTATATATTTAATTTATTTATCTTTTCCCATGTTGGATGAGTTAGAAAGCCTTTCCTACTCATCTTTTACTCTCTTTTACAATTAGATGTTCTTTCCTCATTCCAAAGATTAGCTTCTTTGTTGACATCTATCTTTTAAAGCAAAAAGCCTTTTTCCTTTGAAACTTCTCAGAATTTCTACTTGTTAATAACCTCTTTCTGTATTCTTTTTGTCAGTTAGGTCTTTTTCAGCTAAGTAGTCTTCAGATGAATTTCAGGTGGTTAAAGCTACCAAGTAAAAACATTTTATGAATATTATAAATTAATTAAGTTGTAATTTGCAAGTATATTTTTCTTTTGGGATTAAAATACTTTGAGTTTGTTACACATTCATGGGAATAAATTATTTACCTTAATGATTATTGTGGAATTATTTATTTAAACTTATATTTGTTGTTTTTTTGTACTGAAAAAGTTATGAAAGCTGATGTAGAATTATGAGCAAGTGAAACAGTTTTAAAACCTAGTTTCTTTTGTATAG
Seq C2 exon
GACTCTCAAATGGTGGTAGACTCCTTCAAATCTGGTTTTGAACCTCCAGGAGACTTTCCATTTGAAGATTACAGTCAACATATATATAGAACCATTTCTGATGGGACTATCAGTGCATCCAAACAGGAGAGTGGGAAGATGGATGCCAAAACCACAGTAGGAAAGGCCAAGGGCAAATTGTGGCTCTTTGGAAAGAAGCCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137942-FNBP1L:NM_001024948:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.292
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF127872=EcsC=PU(16.8=32.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAAGAAATGGACGAACGAAGGA
R:
GGCTTCTTTCCAAAGAGCCAC
Band lengths:
342-1978
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)