HsaINT0067234 @ hg19
Intron Retention
Gene
ENSG00000128683 | GAD1
Description
glutamate decarboxylase 1 (brain, 67kDa) [Source:HGNC Symbol;Acc:4092]
Coordinates
chr2:171675039-171678659:+
Coord C1 exon
chr2:171675039-171675183
Coord A exon
chr2:171675184-171678596
Coord C2 exon
chr2:171678597-171678659
Length
3413 bp
Sequences
Splice sites
5' ss Seq
CAAGTAGGT
5' ss Score
7.33
3' ss Seq
CTCCCTCTCTCTCGTCCTAGCGT
3' ss Score
10.72
Exon sequences
Seq C1 exon
CCTGTTTCTGCGCCGGACCAGTCGAGGACTCTGGACAGTAGAGGCCCCGGGACGACCGAGCTGATGGCGTCTTCGACCCCATCTTCGTCCGCAACCTCCTCGAACGCGGGAGCGGACCCCAATACCACTAACCTGCGCCCCACAA
Seq A exon
GTAGGTCCCGCCCCAATTTTCTATCAAATGAACTGCAGGGAAGATGGGGGCGCTGGGACGTCGGGAGGCTGAGCTGGCGGAAAGGGAAGGGGGAGCGCGGAGATAATGGAGGCTGGGAAATAAATGGGGCTCTGACCCCGTCCCTGCCAGAGGTCATTCGGCTGTCAGGGACGCTAGGTGACTCCCAGGGCACCGGAAAGCGAGGACCACGCAAGGTCCGAGCAGCGGCGATCGTTGAGGGCTTCGCGGAGGAGGAGGGGCGCGCAGCCAGGGTGTTGTTTTTATTCTGTTGTGTGTGGTTTCTTTGCTCCGTGGGACGACAGGGGTCAGCGCAGGGGGCGGAATGAAGAGCTAGGAGCCCCAGCAGGAATAAGAGTTTTCAGTCCCCGGCTTTCGTTGAGCCAAGATCTGACCTCCTCCTTTCCCCCTGGGCTGTGTTCAAAGTCTATAATCAGCGGAAATTTCGACGTTAATTGCAGCTTTTAGAAAACTCAAGGTCCCTAATTGCTCCAAATTTGCATCAAGCTATTGACGAGTTAGGGAGAAGTCAGGGGCGGGAAAGGTGCATAAAACTGAGACTGAGCCTTGACATTTCATACAATTAATTACATCTCAGAGAAATAAATAAATAAATAAATAAATAGGGGAGCGGGCGGCATCCTGAGTGGCAAGAGATGGGGAACTGGGAGGGGGCAAGAAGCTTTATCATAGAGAGGAGAGAGCACCTCTCTCCTTATCCCAGGCAAGAGATCTGTCAGGAGGTGACATGTCCCGAAAAGAGAGAAAGAAAAGAGACACCAGATAAAAGAGGGGGGAGGATTTATGCTTCCCTGTCTTAAGTGCGACAGGCTCCTCAACCCATTTCCAGAATCTATCTTTAATTTTATTTCCTACCTCTGTAAAGGCTTGAGATGAGAAAATTGTTTTTCTTTTTCCTTGTTGGAGTGAAGAAGTGTCTCCTGACCCCACCCCCCTAAAAAAACTTATCAGCTTCAGACTGTAAGTGTTCCCACTCCCCCATTTATTTATTTCTGAGATGTAATTAATTGTATGAATTTCCAGAATTTGTATACAGAAAGGGCTTAAGAAGGATAGTGTGGTTACAGGGAGTGCTTATTGATGCGCTTTTATGGCACTTTATATTTGAGAAAATAAGTATCCTCATCAATGAAGTGGGGATTATTACCGGAAAGCCCCTTTAGACGCTGGCATTGGCTCCCGGGCAGGAGGTCTCGTGTTAAGTCCTCAGGTCTCATTCCAATTTCCTTTGCAGCTCCCTCTTCCCGCCACCCAGGAGGGATACAATTACCCACACAACAAAGAGGGCCTCGGGAGAGTCGCCAGCCCTGGTAGCATATGAACCAGGCACCGGCGTTGGAGCTGGCCAGGGCAGGGCGGGAGGAACGCGAGGCCTGCGCGCCTTTGTGTGGTGCTTTCGCCTTGATGGATTTCTTTTCTGACGCTTTCCACATTTCCCGCTCCCTTTTGCCGCCTGGGGGTGGGGGTGGGGGGTTAGCGGGCAGTTGTGTTAATTTGCCCTCCACTCCCGGCGCCCTTACGGAATTCCCGGTGGCCGCCAGTCGCCGGCGCAAATGCCAAGTCACCGGTAGGAGACACAACAGAGGCGATGACCTGAATCCGCACGTGGCCTGGTTCGCCTGGAAGCTGCCAAAGCGAAGGCAAGAGAGCCCGGGACCCTGCTGTAAAACAGCAAGCAGCACGTGTCCCAGGCACACTGTTGCGGGCCCTTAGCCTAGCTACGCATCCGCACCCCAGGCTTCAAAGGCGCGCTGGGCGCTCTATCCACTCTCACCCTCCCTTGCAGACAATACCTTTGCCCGCCCAGCTGGCTCCACTTCTTTGCCCCTTTAGAGTCTCCTGGGAGGTGGCGTTAGTGCAGGCAACCTAAGGCACTCTCTTGTTCCAGAAACCCTTGGGTGGGGCTTGGAGCCCTCCTTGTCCCCAACCACTAGGTCTTCCCGACCCTTGCTACATCAAAGGGGCTCTCTCGCTTGCTCTCCCCGTCTCCCTTTCCCTTTCTTTCATTGCAACCCCCAATTTTGAAAGGCAGTGCAATGTGTCTGAACTCCAACTTCCCTGTTGATTGACCTTGGAAAACTCATGTAACCTCTCTGAGCCTCGATGTTTTTTCTTTGTCAAATGACTCTTAGATCAACACTCCTGCCAGTTTCATAGGACTGTTACGAGAATTAGATGAGATGATGTTGAAAGTGAAAGCACTTTATCAGGTCCAAATAGCTCTTTATCCGCCAGGTATTATTAGGGTTTCGCTTTTGCACTGATTTCCTGTCTGTCACTGGAACTCCATCTGTGACATGTCTTACCGACGTCAGGCTGTTTCTTCTCCCCGCTGGGGCTCTGTTGTGCCTCAGGTTTAATGGATGTCACTCTCCTTATCGCCTCCAACACCTGTGCGAAGCTGGAGGCACCAGTCAGGGTAGGGTAAGCGAGTGCTTGGAGAGGTTTGCTTTGAGAGATTGGAAGGGGATTTCGTGCTGGGCTCACCACACCACTCCGCTTGGGGGCTTAGTGGGGATGGGGCTGCTTCCCACGCTTCTTGCTGGAAGTTGAACCCCGAAGGCAGCAGGTAGACCTTGAGGGGTTTGAGAACAGCCTGGAAAAGAAGGAAAATCCAGCAGCACCTCCACCCTCAGTTGTGACTCAGAGGAAAGGTGCTTGATTCCATTTACCTTTGCCTGCTCCAGACCCAAGATGTCAGAGGGAAGGGTTAATGAGGGGCAGGTTGGGAAGAGGGGCCAGGGATGAGGACCTGAGGCGCACTATTGTCTTCCCCACTCCCCGGTCTGACTGAAGAGCAGCCATGCGAGCCCGATCATCTAGTCAAATACTATTTTTCACCCAATTAATTCTTGAACTCTTCCACGACCCCATTTCATGCCAGTTTATTTTAAGCTGCCACTAGGCTGGAGACCCGCCAAGAAATTATGAGACGTTTCGGTCCCAGATGCCTGTGTTCCCTTTCTGGGCTGCTGTGGTCGCCCTTTGAGTCTGCGGGGCCCGGCCAGTGGGTGTTGGGCAGCTCGATCGGAGCCTGGCCCTTTGCGTGTGGGTCAGCCTTCACCCAACTCCGACCCCACCTCCGGAGCTGCCGGGCGGGGGTCGCTTACGGGCCCGGAGGGGCGCCGGGTGCCCCGCCTCTCAGAGACACCGTTCCATATTTGAAGCCAGGAGCAGGAAGGGAGTATGATGGGGGCTTAGAGTATATGCCTGTCGGCTCACAGATTTGGCTCCTAGCTCCTTTCAGGAAGTAGCTTTTAATGAAGAGCTCTGGCAAAGTCCTCATCCTCCCCCAAGAAAACCATTGTCCTCCACCCATTTCCCCGCGGTCGGAACCTCCCTAACCGAACCTCTCTCCCTCTCTCTCGTCCTAG
Seq C2 exon
CGTACGATACCTGGTGCGGCGTGGCCCATGGATGCACCAGAAAACTGGGGCTCAAGATCTGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000128683-GAD1:NM_013445:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.816 A=NA C2=0.003
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)