HsaINT0068280 @ hg38
Intron Retention
Gene
ENSG00000106633 | GCK
Description
glucokinase [Source:HGNC Symbol;Acc:HGNC:4195]
Coordinates
chr7:44152271-44153463:-
Coord C1 exon
chr7:44153301-44153463
Coord A exon
chr7:44152426-44153300
Coord C2 exon
chr7:44152271-44152425
Length
875 bp
Sequences
Splice sites
5' ss Seq
CAGGTACCA
5' ss Score
7.88
3' ss Seq
ACTTCTCTCTGTGCCTTTAGAAG
3' ss Score
9.01
Exon sequences
Seq C1 exon
GTAGAGCAGATCCTGGCAGAGTTCCAGCTGCAGGAGGAGGACCTGAAGAAGGTGATGAGACGGATGCAGAAGGAGATGGACCGCGGCCTGAGGCTGGAGACCCATGAAGAGGCCAGTGTGAAGATGCTGCCCACCTACGTGCGCTCCACCCCAGAAGGCTCAG
Seq A exon
GTACCACATGGTAACCGGCTCCTCATCCAGAAGCAGCTGTGGGCTCAGCCCTAGCTGGGAGAAGCACCCCAGGCACTCCCAGACTCACAGCCAGCCCGAGACAGAATCTCCTGGGGAGCAATGAAGTCCTCGACTTGGGCCAGTTCTCACCCTTGGCTCCTCTGGTCCGGCCCTGGGGCACTCGGGCTCACCCTGGAGCTGGCAAACCTCAGGAAAACTGGCGTTTTAAATCTCACTCCTGGCCAGGTGCAGTGGCTCACCCCTGTAACTTCAACACTTTGGGAGGCCAAAGCAGGCGGATCTCTTGAGGCCAGGAGTTTGAGACCAGCCTGCCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTATCCAGGCATGGTGGCACATTCCTGTAGTTCCAGCTACTCGGGAGGCTGAGGCATAAGAATTGCTTGAACCCGGGAGGCCGAGGTTGCAGTGAGCCAAAATCGCGCCACTGCACTCCAGCCTGGGGTGACAGGGTGAGACACCATCTCAAAAAAAAAAAAAAAAAAAGACCTCACTGCTCCCCATGGGCACTTAGGGAACTCTCCCAGCCCAGTTCTGCAGCTGGGCCATTGCACTAGATCCTCAGTTGGTCCCTGGGCTCTCGGTGACTGTCCAGGGCAGGAGTTTCCCATTGACTTTTCCCTGGTTGACCTTTGACCCCTTCCACAGTTGACACTGGTGTCCCCAGGTGTCTGGTGGCCCCTTGTCCAGCTCCCTTAGTCCCTTGTGCCTTCCCTCCTCCTCTTTGTAATATCCGGGCTCAGTCACCTGGGGCCCACCCAGCCCAAGGCCAGCCTGTGGGTGTCCCTGAGGCTGACACACTTCTCTCTGTGCCTTTAG
Seq C2 exon
AAGTCGGGGACTTCCTCTCCCTGGACCTGGGTGGCACTAACTTCAGGGTGATGCTGGTGAAGGTGGGAGAAGGTGAGGAGGGGCAGTGGAGCGTGAAGACCAAACACCAGATGTACTCCATCCCCGAGGACGCCATGACCGGCACTGCTGAGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000106633:ENST00000403799:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.391 A=NA C2=0.064
Domain overlap (PFAM):
C1:
PF0034916=Hexokinase_1=FE(26.0=100)
A:
NA
C2:
PF0034916=Hexokinase_1=FE(44.7=100),PF0034916=Hexokinase_1=PU(2.4=3.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTAGAGCAGATCCTGGCAGAGT
R:
CATCTCAGCAGTGCCGGTCAT
Band lengths:
318-1193
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development