HsaINT0076826 @ hg38
Intron Retention
Gene
ENSG00000180448 | ARHGAP45
Description
Rho GTPase activating protein 45 [Source:HGNC Symbol;Acc:HGNC:17102]
Coordinates
chr19:1077857-1079840:+
Coord C1 exon
chr19:1077857-1078045
Coord A exon
chr19:1078046-1079702
Coord C2 exon
chr19:1079703-1079840
Length
1657 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
3' ss Seq
GCGCCCCGCCCCCACCGCAGGCG
3' ss Score
7.47
Exon sequences
Seq C1 exon
CAAGAGGCGGAGTCCAACCTGCGCAAGGCCAAGCAGGGTTACGTGCAGCGCTGCGAGGACCACGACAAGGCTCGCTTCCTCGTGGCCAAGGCGGAGGAGGAGCAGGCTGGCAGCGCGCCGGGAGCAGGCAGCACGGCCACCAAGACCCTGGACAAGCGGCGGCGGCTGGAGGAGGAGGCCAAGAACAAG
Seq A exon
GTGAGGGCGGGTGGAGGCAGGGCTGGAGGTCCCTGGAGGAGGAGATCCAATGCTTGGTGTGACATTTACTACCTCCAGACCTTTGTTTTTGTTTTTTTGTTTTTTTGTTTGTTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACAGTCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGTCCACCTCGGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCCACTGCGCCCGGCCAATTTGTTTTTTGGAGACAGAGTCTCATTCTGTTGCCCAGGCTGGAGTGCAGTGGTGAGATCTCACTGCAACCTCCGCCTCCCAGGTTCACACAGTTCTCTGCCTCAGCCACCCTGCCACCAAGCCCAGCTAATTTTTTTGTATTTTTAGTAGACACAGAGTTTCACCATCTTGGCCAGGTTGGTCTCAAACTCCTGACCTCATGATCCACCCACTTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCCCGATTTTTAAATTATTATTATTTTTGAGACAGTGTCTTGTTCTGTCACCCAGGCTGGAGTGCAGTGACGTGATCATGGCTCACTGCAGCCTCTACCTCCTGGGCTCAAGCAATCTTCTCGCCTCAGCCTCTAGAGTAGCTGGGACCACAGGCGTGTGCCGCCACACCCAGCTAATTTAAAAAAATTCTTGGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACAAGGTCAGGAGATCAAGACCATCCTGGCTAACAGGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTAGTGGTGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAAAATGGCATGAACCCGGGAGGTGGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAACGAGACTCTGTCTCAAAAAAAAAAAAAAATTCTTTATAAAGATGGGGGTCTCAGGCTGAGTGTGGTGGCTCACACCTGTAATCCCAGCCCTTTGGGAGGCTGAGACGGGCAGATCATATGAGGCCAGGAGTTCGAAACCAGCCTGGGCAACATGGTGAAACCCCTGTATCTCTACTAAAATTACAAAAAATTAACCGGGTATGGTGGGTGGGGGGCACCTGTAATCCGTTACTTGGGAGGCTGAGGCAGAATTGCTTGAACCCGGTAGGTGGAGGTTGCAGTGAGCTGAGATCGTACCACTGCACTCCAGCCTGGCCTACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAGATGGGGAGGGTCTCACCATGTTGCTCAGGCTGGTCTCGAACTCCTGGCCTCAAGCAAGTCTCCCACTGTGGCCTCCCGAGGCGCTGGGATGACAGGCGTCAGCCCCGCCTCCCTGAGGTTTCTGTCTGAGTCCTGCACCCCGGGCTGAGGCCTCTCTCTGTGCGCCCCGCCCCCACCGCAG
Seq C2 exon
GCGGAGGAAGCTATGGCCACCTACCGCACCTGCGTGGCCGACGCGAAGACGCAGAAGCAGGAGCTGGAGGATACCAAGGTGACGGCGCTGCGGCAGATCCAGGAGGTCATCCGGCAGAGCGACCAAACCATCAAGTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000180448:ENST00000539243:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.782 A=NA C2=0.428
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGAGGCGGAGTCCAACCTG
R:
CGACTTGATGGTTTGGTCGCT
Band lengths:
326-1983
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development