HsaINT0083187 @ hg38
Intron Retention
Gene
ENSG00000150995 | ITPR1
Description
inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]
Coordinates
chr3:4663065-4665296:+
Coord C1 exon
chr3:4663065-4663206
Coord A exon
chr3:4663207-4665137
Coord C2 exon
chr3:4665138-4665296
Length
1931 bp
Sequences
Splice sites
5' ss Seq
CAGGTCGGT
5' ss Score
7.53
3' ss Seq
CTTTTCATTTTCACAAACAGATC
3' ss Score
10.07
Exon sequences
Seq C1 exon
GTCTGTAACCAAGCTGCTAGAAGATTTGGTTTACTTCGTCACTGGTGGAACTAATTCTGGTCAAGATGTTCTCGAAGTTGTCTTCTCCAAGCCCAACAGAGAACGGCAGAAACTGATGAGAGAACAGAATATTCTCAAGCAG
Seq A exon
GTCGGTGAGATGTGGCGTACTGGGGATTTGGCTTTATGAGAAATCATAAAGCATGAGTGGTAGCTCATGCCTGTAGTCCCAGCACTTTGGGAAGCCGAGGTGGGAGGATCCCCTTGAGCCCAGGAAATGGAGGTTGCAGTGAGCTGATCGCATCACTGCCCTCCAGCCTGGGTGACAGAGAGAGAGCCTGTCTCAAAAGAGAAAGAAAAAGAGAAATCAATGGGATCATTGAGGGATATTGGTGATTCCCACCTCAAAGGCTTGATGAATTGATTTTTCAATAGACTATTTTCTAGAGCAGTTTTTAGGTTCTCAGCAAGATTGTGCAAAAAGTCCAGAGAGTTCCCATATCTCCTCTTGTCCTCACACACTTGGCCTCCCCCACTACCGACATCCTACATCACAGTGAGACATTTGTGACAATTTGGGGAATCAACATTGATACATCATTATCACCTGAAGTCCATAGTTTACATTAGGGTTCTCTCTTGGCATTTTATTTTCTATGGGTTTTGATAAATGTATGATGCCATTTAGTCACCATTAAAATATCTTACAGAATAGTTTCACTGCCCTGAAATCATCTGTGCTCCTCCTATTTGTCTGTCCTTCCTGCTAACCCTTCACAGCCATGAACGTTCTTACTGCATGCATTGTTTTCCCTTTACAGAATGTGACATGGTTGGAATCAAACAGTATGTACCCTTTTCAGAGGGGCAAATTTCACTTAGTGATATGCATCCAAGGTTCTTCAGTGTCTGTCCATGGCTTGATAGTTCAGTTCAATTGATTTTTAGCGTACTTGTTGGATATCAATCATGTGAGAGTTTACCTGTTAGGAACCTCAAGAAACATTCAGCTGACAACTTTATTTTCCTCAAAAATAATGTAAAGTTCAATGTGACCTTAAGGTTATTTCATACATTTGGGAGATTTGGCATATTCTATAAACTCAGAAGGCCCATATAGGCTCTTATAGAGTGCCCTATAAGTCACCACAGAATCTTTCCGTAAAGAATGAGTAGTGGTTGACAGGAAATACATAGATGATATTGTTGGATGTAAATGTAAATAAACTGGTATAAAGACAAATTAGAGGCAGTAAAGTGACAAATCCAGAGTAGATTAAATGCACAGAGATGCATACCATGTCCTTCTGTAACCCAACTGGAGATTAGCCCACAAACTTGCCACCGGAATTCCTGGCCACCAAAGCTAAAAGAGAAACATATTAGTTACAAGTCCCACTGGTCCCCATGGAACAAGGGATTTGAGATTATTTTTTCATGTTGGTCTATGATAGACAGAATTTATTAACAATCCATCTTGTTTCAACAAGAATTTCCAGTTCAAGAGTAAATGTCCAGCTGTTGTTTCATGTGATGATTCTCAAATTAGACCTCTGGCTTAATGCCCATGCTCATTTGTACAATAGTAATTCCTGAGAGGCAAAAAATAACTGACTCACTGGCAGGAGCCTTCATTGATTACTTGTGCTGGGCACTAGTGCGACTTAAAATTATCATCCATTTTCATCCTTACTACACCTCTGTGATATAGGCATTATTCTTTCCATTTTGCTGGTAAGGAAATGCGGGTTTACTTTGACTGTAATCTGTACTGCTAGGGAGTAATAAAGGCTTGTGTTTCCACCTAGAATCTGCTGATTCCATTGTCTGTGTTCTTAAACGCTTTGCTCTAAGCACTGTGCTGTTAGGTGTATGAGGACCAGTGGAGTCCAGTAGACTTAATTCAGCGCGTCTCCCATCTCAGTTGATGGGCTGAATGCAGTGTTCAGGTTATGGATGTGTTGGGATAGAGAAATTTTCTAATGTAATCCAGCCACCCTTGAGCTTGCATTACTTCCAAACAGAGGGTTAGCTTTGAAGCCCTAAGTGATTGCCATTTTTGCTTTTCATTTTCACAAACAG
Seq C2 exon
ATCTTCAAGTTGTTACAAGCCCCATTCACAGACTGCGGTGATGGCCCAATGCTTCGGCTGGAAGAGCTCGGGGACCAGCGGCACGCTCCTTTCAGACACATCTGCCGGCTCTGCTACAGGGTGCTGAGACACTCGCAGCAAGACTACAGGAAGAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000150995:ENST00000357086:16
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.021 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0136516=RYDR_ITPR=PU(22.3=95.8)
A:
NA
C2:
PF0136516=RYDR_ITPR=FE(25.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTGTAACCAAGCTGCTAGA
R:
TTCCTGTAGTCTTGCTGCGAG
Band lengths:
294-2225
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development