HsaINT0083228 @ hg19
Intron Retention
Gene
ENSG00000150995 | ITPR1
Description
inositol 1,4,5-trisphosphate receptor, type 1 [Source:HGNC Symbol;Acc:6180]
Coordinates
chr3:4854826-4856246:+
Coord C1 exon
chr3:4854826-4854918
Coord A exon
chr3:4854919-4856106
Coord C2 exon
chr3:4856107-4856246
Length
1188 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGA
5' ss Score
9.45
3' ss Seq
GTTACTTGCCGTGTTCACAGAGC
3' ss Score
6.41
Exon sequences
Seq C1 exon
AAACCGGCGAGAGTTTGGCAAGCGAGTTCCTGTTCTCCGATGTGTGTAGGGTGGAGAGTGGGGAGAACTGCTCCTCTCCTGCACCCAGAGAAG
Seq A exon
GTAGGACCTCCTAACTGTAAGCCCCATGTTAATATCGGACTCCTCCAGAGGCTTAGCTGATGCAGGTGATGTTGGAAGAAGATTAAATTTACTGCTCAGGAGTAAGGCTATAGCAAAGGGGAAAGGCTGAGAAAGAGGAGGGAGATGAAGGGAAAAGAAGGTTACACCTGAAGAAAAGATCTGATGTGATTCAGCCGATTTATACTGAGTGCCCGCCATTTGCCAGGGACTGTGGTGTACTCTAAGAGACAGTAATGTAGTGGAGGGTGCGGGCAGGCCAAATGGTGATTGCTAGAGAGTTGCCCAATGCTGGGAATAAGGATGGAATACAGAAGTTAGGCACCCGGCCTACTACTGGGCTAAGCGTATCATCAAGAAAGTGATATCCAAACTATAAAAGGAGACTCTTGATATTCCAAGGAGAGGGAATAGTACATCTAAAGGCTTTAAAGGTAAAAAGAAAAAAACAGCAAGTTTGGGGAGATAATGATTATAAGGAAGGAGAGTGGCAAGAAATGAAGCCACAGATACAAACAAAGGGCTAGATCATGAAGGATCTTCTATGTCAGGCGTAGGAGGTTAAACTTCGTCCAGAGGATGGTCAGGGGTTGTTGGAAGATGAGTGATGAAATCTGTGTTTTAGCAAGACCCTCTGCAGCTGGAGAAAGGAATGAGGCACACAGCAAGGCATGGCTCTTACTGCATAAACCAGTGAGAATGAACAGCCTCCAATGTAAAGCAGTTGATCCAGAGGCCCTGCCGTGAAATATCCCTGGATATAGTCCTCACACCATTCCCAGTGAGGAACCTGTGTCCTGTGGCATAACCCTCATCTGAGAGACAAGAGGCCTGTGACTCAGAGTTGCGAAGCAACTCATCTGACATGAAAAGACTGTTTGCGGCTGGGTCTGGGGTTTAAAACCTGAAAAGGACAGGGCATGTTTTAGATCCCACAGAGGGAGAGCAATACTACCATAGCTGGAGAAATTAGCGGGGGTTAGCGATGAAAACAGTTGCCCCAGACGACTTTAGCTTTTGAAAGAAAATAAGAAAATTCTTGGCTCTTGATTCCTTAATTTTATTCTTTCGTGTGCCTGGTGAGATGGCATTCAGGAAACAGGATTTCAAAATCCCGGTCTCTCTTTTCTCCTCACGTTTTCTCTCTGTTGTTACTTGCCGTGTTCACAG
Seq C2 exon
AGCTGGTCCCTGCAGAAGAGACGGAACAGGATAAAGAGCACACATGTGAGACGCTGCTGATGTGCATTGTCACTGTGCTGAGTCACGGGCTGCGGAGCGGGGGTGGAGTAGGAGATGTACTCAGGAAGCCGTCCAAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000150995-ITPR1:NM_002222:53
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.125 A=NA C2=0.191
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(12.1=100)
A:
NA
C2:
PF0052026=Ion_trans=FE(17.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAACCGGCGAGAGTTTGGC
R:
CTCTTTGGACGGCTTCCTGAG
Band lengths:
233-1421
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)