HsaINT0083347 @ hg19
Intron Retention
Gene
ENSG00000096433 | ITPR3
Description
inositol 1,4,5-trisphosphate receptor, type 3 [Source:HGNC Symbol;Acc:6182]
Coordinates
chr6:33627243-33630451:+
Coord C1 exon
chr6:33627243-33627326
Coord A exon
chr6:33627327-33630304
Coord C2 exon
chr6:33630305-33630451
Length
2978 bp
Sequences
Splice sites
5' ss Seq
GGGGTAAGG
5' ss Score
8.05
3' ss Seq
CCACACCCTGCTGCCTGCAGGGA
3' ss Score
7.28
Exon sequences
Seq C1 exon
GTCAATTCTGTGAACTGCAACACCAGCTGGAAGATCAACCTGTTTATGCAGTTTCGGGACCACCTGGAGGAGGTGTTGAAAGGG
Seq A exon
GTAAGGACTGGGAACCCCTGCCCTGCCCAGCTGGCCACCTAGCCCTCCCCACCAGGGCCCTCTTCCTGCCTTCTCCACCCGCCAGGCCTCAGGCCCTTACCCTCTCCCCAGCTTTGCACCCCCCAGCCTCCCTCCACCTCCACAGGGCCCCACCCACATGGCCCTACCAGGGCTGCCGCTTCTCTCGTCTCTGGCCACAGCTCCCTTCTCCATTCTCCCTGGGTCCTGCCTGGTCTTTGTTTTCTCCCTTGTTTAAGGGGGTGTCAGTGGACTGGGGGTCTCCATCCCCCCACCACCCAGAGCCTTTGAGCACCTTCCTCTCCCCAACTCCTGCTGCCTGGATCCACACCAGGCCCCCGCCCCTTGCCCTGTGCCCTCATTGGCAAGCGAGTGAGGCTGCCCTGTCTGCTGAGTTAGGGGTCACCGCCTGTCTCCTTCCTGGTCCCAGACATGCTGGTGTGGGCTCTGGGAGAGAAGGGAGGCCTGGGAAATACTGCAGTGAAGACTTCGGGAGGATCCAGGACTGAGGGCAGAGGGAGCTGTCTGGGGCCACCAGAGAGACCATTCAAGAAACCCTGAACAGCAGATGTGGGCGAGAGAGGAGAGTTCAGATGTCTCTTGGGTGGGGCTGCAAGGGATGGAACCAGCAGACGGGGTGTAGACGGTCTTGAGGGAGGGCAGATCTGTAGAGTGTGAGGCTGTCCAGCTAGGGGAGCAGGCAGGAACATCAGCTGTGAAACCTGTTAGAGGGACAGGTGACAGGCCCGAGAGCAGCCACCTAAGGAGTCTTAGGTGCTCCTCCCTGCTCGGAAGCTGCAATGGCTCCCTTTGCCCTCCTCCCCACGCTGAGCTGCTCTGTTAGACTCTCCTGCCCTGCTCAGGCTGCCTCAGTCCCCCACCCTCCTCATCCTTCTTACCTCCTGGGCTGCTTCCCGTCTACCCATGCCCTGCCCCAATGCCTTCTCCCTCCCTCCCTCCCTTAAATCTGCACATCATCCACACATTAATCAAGGTGCAGCCATGCACTACCCCTCCTGGAAGCCTTCCCTAATGTTCCAGCCCCGAATCTGTGCAGCACTTAGGAAATGAAGCATCTTGGCCGGGCGGGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGTGGATCACTTGAGGTCAGGAGCTCAAGACCAGCCTGGCCAACGTGGAGAAAGCCCTTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGCAGTGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAGCCTGGGAGGTGGAGGTTGCAGTAAGCCAAGATTGCACCACACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCTTCTCAAAAAAAACAAACAAGCAAACAAACAAACAAATAAATAAAATGAAGCATCACTTGGGCCTCACTCTGTGGTCTACATAGAATTATTTCTGGGGAATCCGTCATGGCTCCGTGGTTCCAAGGCAGCTCAGAAGCAAGGCTTTCTGGTGCTAAGTCCACTGCTTTTTTGCCCCTGCCCTGCGCTACTGGGGCACAGAAGTCACTAGGTTCTGCCATAGTAACTGACCCAATCTTTATATCGTCATTCATTCATGCATTCTTGCATTCACTGCTGCATTCACTCTGCAGGTGTTCACTGAATGCTTTGTGTCTAGTGTGTGTTCAGTGGAGGGAAGACAGAAAGTGCCATTAGTGATGATAGCAAGAGTGGCAGCCATGCATTGTGTGCCTGCTGGGCGGCAGGCTCAGCGGGAGGAAGGTGATGGAATGATTAAGGTGCAGGCCCTGGAACTGGGCCAAAGATTCATGTCCCATTTGCCATTAGTTGCATGACCCTCGGCAGGATACTTACCTTCTCTATGCCTGAGTTTCTCCACCCATAAAATGGGGCTAATGATGTATTTACCCAGAGGGTTGATGTGAGGATCAGGTGAGAAAGCTTTCAAGTGCTTGCACAGTGGCTGGCACGCGGTAAGTGTGCAGTGTGACTTCATCACGCATATTATAATCCTCACAATTTCTGCAAGGAGGTCATTGTATTCCCATTTTACAGAAGAGGCAACTGAGGCTCAGACATGTTAAGGAACTTATCTGAGGTCACACAGCTTTTAAGAGCAGAGACAGAGGCCGGGCACAGTGGCTTATGCCTGTAATCCTAGCACTTTGGGAAGCTGAGGTGGGTGAATTGCCTGAGCTTAGGAGTTTGAGGCCAGTCTGGGCAACATGGTGAAACCCCGTCTCTACTAAAAATAAAATAAATTAGCCGGGCGTGGTGGCAGGCACCTGTGGTCCCAGCTACACAGGAGGCAGAGGCATGAGAATCACTTGAACCCAGGAGGCGAAGGTTGCAGTGAGCCAAGATCGTGCCATGCACTCCATCCTGGGCAACAGAGTGACTGTCTCTGAAAAAAAAAAAAAAAAAAAAAAAAAGACAGGATCCAAACGTGGTATCTCTGTCCAAAGCTATGGAGATGCCCTCCATGCTGCCCCCATCCAACAGGGGAGCAAAAGAAGTGGGCATGAGCTACCAATATTTAGGCAGAAAGGACCCTGAGAGAGGGGCAGCCATGGCCCCGGGGACACTGAGGGGGTAAGGTCCCCCTCCTTCATGGAGGGGGTGACTGGAGATGGGCCGTTAGAGGTTAGGCAGGGTGTCTAGAGGTACACATAGGGAGAGAGGTGGTCCAGGGTGGGTTTGAACATGGGAAGGCCTGGGAGAGCTCTGGATTTGGGGTCTGGGATGCGGGCTGAGGGCAGAGTGCCTGGGCTTTGGCTGTTCTCTAGGGGGCTCAGCTTGCATCCCCCTCTCTGTGTGCTGGCTCTGGAAGAGGGGCCCTGCCAGCAGCCAACCCTGTCTGAGGCAGGTGGGGCTGGGCCCTGGGTGGGTCCTTGAGCCTGGAGGGGCCGCAGCCATCCTGAGCCACACCCTGCTGCCTGCAG
Seq C2 exon
GGAGACGTGGTGCGGCTGTTCCATGCGGAGCAGGAGAAGTTCCTGACGTGTGACGAGTACAAGGGCAAGCTGCAGGTGTTCCTGCGAACTACACTGCGCCAGTCTGCCACCTCGGCCACCAGCTCCAATGCTCTCTGGGAGGTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000096433-ITPR3:NM_002224:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF087096=Ins145_P3_rec=PD(8.8=71.4),PF0281514=MIR=PU(2.0=14.3)
A:
NA
C2:
PF0281514=MIR=FE(24.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)