HsaINT0084366 @ hg19
Intron Retention
Gene
ENSG00000173826 | KCNH6
Description
potassium voltage-gated channel, subfamily H (eag-related), member 6 [Source:HGNC Symbol;Acc:18862]
Coordinates
chr17:61607698-61611672:+
Coord C1 exon
chr17:61607698-61607903
Coord A exon
chr17:61607904-61611246
Coord C2 exon
chr17:61611247-61611672
Length
3343 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCGG
5' ss Score
9.13
3' ss Seq
CCCTCGGCCCCCACCCCCAGGTC
3' ss Score
10.47
Exon sequences
Seq C1 exon
AGGGCTCTCATGGCAGGCCAGGCGGACCAGGGCCAGGCACAGGCAGGGGCAAGTACAGGACCATCAGCCAGATCCCACAGTTCACGCTCAACTTCGTGGAGTTCAACTTGGAGAAGCACCGCTCCAGCTCCACCACGGAGATTGAGATCATCGCGCCCCATAAGGTGGTGGAGCGGACACAGAACGTCACTGAGAAGGTCACCCAG
Seq A exon
GTGCGGGCCTGCAGAGCAGGGTGTGCAGAGCTGTGCCAGGCCTCCAGGGTCCCCTCCCAGGCTCTGGGCCCAGGCCCTTCTGGGGCCTTGGCCGATAAAGAGATCCTGCCTGTCCAGCCTCTAATATCTGGTTTGAGCCCCGGGCCTCCTGTCCTGTTTGAGACCTAAAGACCTGAAGGCCTGCCCTGAGGTCACAGCCCTTGTGCCCAGCTCCTAGAGCCAGAGGAGGCTGGGGTCAGTAGGGCCTGTGAATGATGCCACCTCCTAGGCCTGGAGAAGCCAGGGCAGGGGATGGACATGGAGGCCACCATGGGGGCCTGACCAAGGCTCAGCCCGTCACAGGGAAGGAGAGGCAGAGAGGAGACATGCCAAGGCCATACTGAGAGGAGAGCTGGTGTGGGGGGGGGTCCCAGCCCTGTGCCAGCCCTTTGCCTTTGAGACAAAAGCCACCCTCCCTACTTCCTTCCAATGTGAACACAGGATCCTCCTGCATGCCAGGCAGGGCAGGATGAGGCTGGCACCTCCAGCTATCTTTAATCAGCTTCCTGGGGGCCAGGCCCTGAAGGACCCCGGCAGCTCCTCCTTGGCCACCCCAAGGCAGGCTTCCCTGGGTTCTCTGCTCCAGCTCACCCTGCTGTCCCTTCTCATGAGGCCGGAAGCCCTGACCATTCCAGAGGGAAATGCGAGGAGCCCTGCCCGAGGCTCCAGTGACCACAGTCCTGGCACTGACTCCCTGTGTGACCTTGGCCAGGGGAACTATCAGCCCCCTTTCTAGGCCTCAGGGCTTTCATCTGCAGGAGAGAGATGGACTAAATGGTCTCTGGGGACCCATTTGACATTGAGTAGTTCTGGCCCCAGGAGGCAGACAAAGCTGTAAGTCATAGCCAGGGGCCCAGGCCAAGGTTGAGCAATGCAGAGCATGGAGGGGCCTGCTCCCAGCTTTCCTGGGGCTGTCCCTGTGTTGGGGCTGGAGGCAGCTCTTTTCCCCCTGCCTGTTTTCACCTAAAGCACAGTTGCTGCTGGAACCAGGTGTGGGGAAGACCACTCAGCACCTCACTGACCTCAAGGATCCTGAGGAGGGTGGGACGCCAGGCTGCAGGACTGTGTCCTCTGAGGTCAGGCAGAGTGGCCCAAAGGCCTGACCCTGGGAAGCCCCCCAGCTGCTTACTCCAGGACATCTTAGGTTGATGCCACTGTTGGTGGCTACCACGGAGGGGGCTGTTAGACTGGAGAGTGGTCGGTAAAGACAGCCAGGCCTGGCTGGGCCCATAGTCCCGGCACCTGCCCAACCTGCCTACCCGTTTGTTCCTCAGCTTGGCCCCTCTTGGTGTCACTCCCCTGCTCCATGTGGGTCCTAGGTCCAGGGAGGTGCCTGACAGATCTCAGGGGAAAGAGCAGGCGAGGACCCAGATCAGGGAAGTCACATCGGCCTCAACCAGAACTTAAAGAGCCTCGATGGCTGTGGCCTCACACTGGAGCCTGGGCATCCTGAGGGCCTTGCAGCTCTGGGGGACACTGGGCAGGGTGGGCTTTGCCACGAAGAGCCTCGAGCTGGCTTTGGAGGCAGTGGGAGATTTTGGGGGTCCCCCTGTCTGGGGGCCCTGAGAAGCTGAGGAACTCTATTCTCAGCCTACTTTAAACCACCCCCCACCATTCCTTCTGTCTCCCTCCCACTCCCCACCCAGGCAGGCCTAGGGAAGGGCCTTGTTTCACCCTAGCAGGGTCCTAGCAGCCCTCAGGAGGAGGAGGAGCAGCTCTGATGCCCAGGGTGTGACGGCAGCTGCTCCTGATCAGAGCCCCAGTTTGCAGTGCTCATTCAAGGACCTGCAGTTGAGAGCCCATGTGGACCAAGAGCTGGGCACACAGCGGGGAGAGGGCCAGTGAGGGAGCCAAACTCAGTGAGCCCATGGCTCAGTGGAGCACCACCATGCAGCTAGGTGGATACAGGGGCAGGGAGAAAATAAAAAAAGAGCCCAAGTCTATGTGGAGTCGGAGGGGGCTTCCTGGGGAAGTACGAGGTGAGGCCTCAAGGCTGAGCAGGTCACTGCAGGGTGGGGACATGGTAGCCCCACTCAAGGGTTTGGATGTCAGATAGGGACCCTCTGGTTGAAACTAAATGGATCTGCCTTACTGTGATCCCATCTGCTAATTGATTTGGTTTGCAAGGTCAAACCTTACATTGCAAATTTTCCTAAATCAGAACTATCCACCAGATCTCATCTGGTGGGAGAGGAGGTCCATGGAACACCCCTCCGGCTCCATCCTTGTCTGGAGCAGTGTCTGATGAGGCTGAGGGAGGAGGAGGGTGGACAGGGAATTACTGTGTAGAGCAGCACCTGCCATCTCCATGAGAATAGATGGATCTCACTAACTACATGAGAAGAGATGCATCTCATTTCCTCACTACCCATGGCTTTTGTTGTCCTTTGTGATTCCATTTTGCAGATGAGGGAACTGAGGCTCACAGAGGTTACAAAACTTGCCCAAGGCTCACCTATAGCACATGTCAGACCTGGGATTCAACCGGGGAGGCCTGGCTTCAGTACCCATGCCCTTCCTAATGCCCTGGCTGTCTCTCATGTTGGGCAGCTGGGCAGAGCCAGGGCATGTTGTGCTGGGACCTAGAGATCCTGGGTTGATCACAGTCTTGGAGGCGGGGGCGGGAGGGGAGAAGGGAGAAGGGAAGGCTCTGCAGAAGGTGATGATTCCAAACCCTTGGAGATGTGGGGAGGAGTCAGTTTTCCTTGGTGCCCAGGACCCGTTGAGGGTCCAGGTTGGCTACACCCCTACCCCATGGACTCTTTCCATGGGAGGCTCTGAGTTGGCCTCAGAGAGGGCACTCACTGGTCCTGGATCCCCAGGGCCCTCAGAAAGGAAGACATTCTTCTAGGGGTGACCTGTTCCCATCAGGAACCCTGACCATAGGGAGCCTCCTAAGCTCACCAGAGAGGATCAGCCCATCAGCTACCCCTTCTGTGGGCTCTTGTGTGGAATGGGTCTATAGATGTCCATGGGCCTGGCCCTCCCCTGCCTGGCTCCACCCACTCCAGGATGTTTCCAAGGGAGCTTGTGAGCATCAAACCTGGTGTCGCTATGGGGCGGAGCCATACCCCTCCTCTTGCATCCCAACTCCTTTCTCTGCACTTCCTCTCGAGGCATCTGTCCCCTTAGGAACTTGCCTTCTCAGACACCCCCCACCCCATCTCTCCCTCATCCCCTCTGCCCACCAGAGCCGTGGTCACCCACCCTCTCCCACTACACCTTCCCCAGGCCTCAGCCCTCTAGGCCAGTCTCACCAGCAGTGGCTGCCCCGTGCCTGACCTCCCTCGGCCCCCACCCCCAG
Seq C2 exon
GTCCTGTCCCTGGGCGCGGATGTGCTGCCGGAGTACAAGCTGCAGGCGCCGCGCATCCACCGCTGGACCATCCTGCACTACAGCCCCTTCAAGGCCGTGTGGGACTGGCTCATCCTGCTGCTGGTCATCTACACGGCTGTCTTCACGCCCTACTCAGCCGCCTTCCTGCTCAGCGATCAGGACGAATCACGGCGTGGGGCCTGCAGCTATACCTGCAGTCCCCTCACTGTGGTGGATCTCATCGTGGACATCATGTTCGTCGTGGACATCGTCATCAACTTCCGCACCACCTATGTCAACACCAATGATGAGGTGGTCAGCCACCCCCGCCGCATCGCCGTCCACTACTTCAAGGGCTGGTTCCTCATTGACATGGTGGCCGCCATCCCTTTCGACCTCCTGATCTTCCGCACTGGCTCCGATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000173826-KCNH6:NM_030779:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.232 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF084125=Ion_trans_N=WD(100=37.3),PF0052026=Ion_trans=PU(31.0=45.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)