HsaINT0088151 @ hg19
Intron Retention
Gene
ENSG00000168280 | KIF5C
Description
kinesin family member 5C [Source:HGNC Symbol;Acc:6325]
Coordinates
chr2:149854914-149857038:+
Coord C1 exon
chr2:149854914-149855023
Coord A exon
chr2:149855024-149856936
Coord C2 exon
chr2:149856937-149857038
Length
1913 bp
Sequences
Splice sites
5' ss Seq
GGAGTGAGT
5' ss Score
6.05
3' ss Seq
CTTTTTCCTCTCAATTTCAGTTT
3' ss Score
10.94
Exon sequences
Seq C1 exon
AAGGCGCTGGAGCAGCAGATGGAGAGCCACCGGGAAGCTCACCAGAAGCAGCTGTCCAGACTCCGAGACGAAATTGAGGAGAAGCAGAAAATCATTGATGAGATTCGGGA
Seq A exon
GTGAGTCGGCCCAGGGCACCAGGGGTGTGGGGGTGGTCATGCCTCGGTCCTCTTGGGGAAGCCTGGAAGGATGTGGCTCTTAGTCGAGGGCCCTGCTCACCTTGCCCTGTGGGCACTGCCCTGGTGACACAGCAGGCTGGGCGGGCTGCTTCCAAGGTCTGTTCTCCGATCTGGAGCTGAGCCTCCTGGAGCCCTGGCATGGCAGGTGGCAGGCGGGCCCAGCTGCCTCTCCTAGTCCCCGAGGGCCAGGGTCACATAGGTGATTCCGCTGGATGGACGCATGCCCCAGTAGATGGGGGGGAGCATCTGTAATGAAAGCACCAAAAAAAAAAAAAAAAAAGAAAAGAAAAGAAAAGAAAAAAAAAAAATTTGGTCCTGACTACAGGATTCTAGTAGGTTAATAAACACTCGAGAGAAGACAGCACCACCGCCTCCCCTTCTCCCCCTACACATACACGCTCACTGGGCAACCCAGCCACCTGGTTCCATGTGCTCACTTCTTAGGGCCCCACACTGTCATGTGTCTGTGCAGGTAGAGGTGCCAGTGACCTGTGGCACTGCCACCAGGATGGCATCATTGCAGTTTCTCTCAGGTGACACCCCCTCATGTTGTGCTCCTGCCTTGTCGCAGCCTCTGACATGCCCTCTGCTCCTTCAGAATAATGTTTTCAAATGCTCTGCATAAAAGACCTGGGATTACAAAGAAAACCAATTATATTGAAATGCTGACCTCCCCACCCCCACCCCACCCAGGGTCTACACTGTTCCCTCCCCTCCCGCTTTCTGTAGATGAAGAAACAGATTTCTATATGGGAAGCAAGGCGAAATGATTTACTTAAGGTCACATTGCTAAATAGGAATCAGATTGGAGTTAGACTTTAATTCTCCAGACTACTGATCCAAGTCCCTTTTCAATGTGTGTGAGCCGCTCGAAAGGTGCATTTGCATTTTAAAAGAGGAGAATGGTAACCCAAGCAAAAGTCTAAATGGTGTGACCCAGGCTCGGTGCCCAGTTCCTGAAGGAAGGCACTTAGCCTCCTCCCTCTTTTTCTCCTCTTCGGCCATCCCCTGCTGTTGCCATGTTGTGCTTTTCCCCTTCAGGGATATCTCACATTCGTTATTCTGATTAATCACCCTCACAGATTCGACTGGAAGGGAGGGGGAGGTTGGAGGGAAGGAAGAGGGAGAAAGAGGGTTGGTTGGTGAGTGAGTTAGGTGGAGGGGGAAGCTTCCCTGGCTTGTGCCTTTCAAATGGACTCTGGGTTTTCCTTCTGGTAGTGCATAGCTGTTCCTTTACAGGCGCTTAGGCGTGGCTCTAGGAAAGGTTTTATGAGTCCTGGGCTGATGTAAATGTTGACCAAACACCCTCAACCAGATGGCGAGTTTCTGTTTGCAGCAGAGCCCAGGCTGTCTTTTCTTCATAATTCTCTCTGTGCCCACTCCTCGAGGGCAGGAACTGTCCCTGTATCAGTGAGGCATTCGGACTTGGGAGATGTTTTTAGAACATCAGACCAGAAATGAGGGAAGGTGGAAATGGCCAAATCAGGTTCCCCAAGTGACTGCATGCCATCCGAGGGGCCGAGGAAGCAGAGTTCTTCTGACATGGGCTCTCTGTTTTAAAATATCAGCCCTTCTCCCATCTCATTATTTTTCCCCTGAAGCTCTTGCACAAGCAAACTATAAATACATCCTCAAAGCCTTATGTTTCATGACTCTTAGATGCACCCCAGAAATTAGTTTTCACTTGGGCACGGAGGAAGCTGTGAGGCTGTTCTGTGATCCCTCCAAATCCTGCAGAATTACTGCCTTTATTGTACAGAGCTAATAGGGTTGGAACAGAACCACGGTTTTAGCCTGATGACTCAGAATTTCAGACTGATGTGGAATATATTGCTTTTTCCTCTCAATTTCAG
Seq C2 exon
TTTGAATCAGAAACTGCAACTGGAACAGGAGAAGCTTAGTTCTGATTATAACAAGCTGAAAATAGAGGACCAAGAGAGAGAAATGAAGCTGGAAAAGCTCTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168280-KIF5C:NM_004522:19
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.568 A=NA C2=0.143
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGAGCAGCAGATGGAGAGC
R:
TTCCAGCTTCATTTCTCTCTCTTGG
Band lengths:
198-2111
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)