HsaINT0088901 @ hg38
Intron Retention
Gene
ENSG00000164344 | KLKB1
Description
kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371]
Coordinates
chr4:186254588-186256087:+
Coord C1 exon
chr4:186254588-186254763
Coord A exon
chr4:186254764-186255991
Coord C2 exon
chr4:186255992-186256087
Length
1228 bp
Sequences
Splice sites
5' ss Seq
CTGGTATGT
5' ss Score
8.14
3' ss Seq
ATTTAAAAATTATGTTTCAGAAT
3' ss Score
7.09
Exon sequences
Seq C1 exon
GCTTCCCCTGCAGGATGTTTGGCGCATCTATAGTGGCATTTTAAATCTGTCAGACATTACAAAAGATACACCTTTCTCACAAATAAAAGAGATTATTATTCACCAAAACTATAAAGTCTCAGAAGGGAATCATGATATCGCCTTGATAAAACTCCAGGCTCCTTTGAATTACACTG
Seq A exon
GTATGTAGCATATGTAAGAAGGTGGAGAGCAGAATTGCGCTGGTTGATATTTTCATATCAGTTTGAACAAGAGGGCAGACCTAGAGAGACTGTCGTCGTTTTCTGACTGGTGGAGTTGAGGGAAACGTGAGGGTTGCTGGGAAGTGAAGACCCCGCGACTTGCCGTGAAATCTCTTCTACTTAAAGAGCAAGACATGTGAATTAATTCTTTCAGGGAGGGATACAACTGCATGCAGGTGATGGAAATAATGGGCGTGGGAAATGTCTGTGCCGTCTGAGAGGCACTGGGCTTGCTTTGACAAGAGTAGCAGAACTGTCATTGCTTTGGGCTTAGGGATATTCGAATGTGTGAGGGCAAGTGGGATCAGATATCTACTTCCAGGTATAATTTGGGTAGGAAAGAGACTCATGCAGAAAGAAGCCCTGGAAGGCCAGAGCATCGTGGTCAGAGGTGTTGCCTTTGGAGGGTCATTGCTGCCAGGAGCCGAATACCCACTGTATCCAATAACATTCATGGTCAGGAATGGTGGCTCACACCTGTAATCCCAACACTTTGGGATGCCCAGGTGGGAGGATTGCTTGAGGCCAGGAGTTTGAGACCAGCCTGGGCAACACAGTGAGACCCCGTCTCTACATAAAATTAGAAAAAAACAATTAACTGGGTGTGGTGGTGTGCACCTGTAGTCCCAGCTAGTCAAGAGGCTGAGACAAGAGGATCTCTTGAGCCCAGGAGCTCAAGGCTGTAGTGAGCCAAGATCGTGCCACTGCACACAAACAATTATGTGACCTCGGGCAAGTTGCTTTACCTCTTTACACCTCTTAATTTCCTTATCTGTAAAATGAGGATGATAATTTCTTCCTGGGTCTGTTGTAATAATTAATACATCAAAGCACTTCATGTCTGGAACAGTGAAGATACCCTGCTATGACTATTAAGGATAGTATACATGGAATAAGACACAGGAACTTCTAAATGCTTTTGACCATAGATTTAGGTTCTGAGTTTTAAGAATTTAACTCAGGAAATTGTAACACCAAAAATGTCATGTGAAAAATGGTGGTGACAAATTTTCTTGAATCATTAGCCTTAGAGGTTGGGCAGAAAGCAAAAAATTATTCTTGATGCTACTCTATAGAAAGAGAAGACAGAAAAAGAGAAAGATGTATTTTTAAAGTCTATATCCATAACTTTATTTGACCAAACTCTAATTTAAAAATTATGTTTCAG
Seq C2 exon
AATTCCAAAAACCAATATGCCTACCTTCCAAAGGTGACACAAGCACAATTTATACCAACTGTTGGGTAACCGGATGGGGCTTCTCGAAGGAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000164344:ENST00000264690:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(25.5=100)
A:
NA
C2:
PF0008921=Trypsin=FE(13.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCCCCTGCAGGATGTTTGG
R:
TCTCCTTCGAGAAGCCCCATC
Band lengths:
268-1496
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development