HsaINT0088909 @ hg38
Intron Retention
Gene
ENSG00000164344 | KLKB1
Description
kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371]
Coordinates
chr4:186250243-186251328:+
Coord C1 exon
chr4:186250243-186250402
Coord A exon
chr4:186250403-186251218
Coord C2 exon
chr4:186251219-186251328
Length
816 bp
Sequences
Splice sites
5' ss Seq
AAGGCGAGT
5' ss Score
2.72
3' ss Seq
CTTTTTTTTAAAAAAAATAGAAA
3' ss Score
2.69
Exon sequences
Seq C1 exon
GTTGCCACATGAACATCTTCCAGCATCTTGCGTTCTCAGATGTGGATGTTGCCAGGGTTCTCACTCCAGATGCTTTTGTGTGTCGGACCATCTGCACCTATCACCCCAACTGCCTCTTCTTTACATTCTATACAAATGTATGGAAAATCGAGTCACAAAG
Seq A exon
GCGAGTATGCATGGAAAATCGCATCACAAAGGCGAGTATGCATGGGGAGCACTTGCTGCTGTACTTTCATCACTTTTATAGTCTGAGTTCTTAAAAGTTTCGTTCATTTCCCTCAAAACACTTGAACCTGCAGTTTCAGTAGGTACTGTTCTGCCAGGTGCAGATTAGTTAAGAGATTAGCAGACTTCTCTGCCTATCTTCTCTTACTTTAAAACAAATGTTACCATTGAATCAAGGAAGCAATAGCCATGAGAAAAAAGAAGGATCTGACGCCTTTGAATGAAGATTCAAAACATGATCTTCATGTTTTGTATTAGCTTGGAGTAAAATCCACTTGCTGGCAATATAGCCCTTAAGCTTGTTGCCTCTTCTCTTTGTTTCAGAAACTAGAGCCCTGTTTATTCTGATCAAGGCTCTGGCCCACTGTCTTTATCTCAGATAACCCACCCTCTTCTGCACACAGCATGGAGCTAAGAGAAGGGTGTCTAGTTATGTAATATCATCGGCAGCATAAATTCCCAGAATTTGTTCTTTGATTTTTTTGTTTGTTTTTCCAGTTAGAAGGTGGAACTTCATCATTGTCCTCTTTTCAGGTTGTCTGTGCCTATTAGTTTTCTCCAGAGGGAGAGGTGGCTTGATTTACATTTAATCTCTGCAATTTATTAGAGTCCTGTAGTTGGATTTACTTTGAAGAGAGTTTCCCAGAAGAATAAAATTTGCTGCGTTGCTTTTTGGGTGTGAGCTGCTTTTGTATTTGCCTAATGCCTTTAATGCAAATTTCTTTCTTTCTCTCTTGCTTTTTTTTAAAAAAAATAG
Seq C2 exon
AAATGTTTGTCTTCTTAAAACATCTGAAAGTGGCACACCAAGTTCCTCTACTCCTCAAGAAAACACCATATCTGGATATAGCCTTTTAACCTGCAAAAGAACTTTACCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000164344:ENST00000264690:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.132
Domain overlap (PFAM):
C1:
PF0002421=PAN_1=PU(61.9=96.3)
A:
NA
C2:
PF0002421=PAN_1=PD(36.9=81.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTGCCACATGAACATCTTCCA
R:
CAGGTAAAGTTCTTTTGCAGGT
Band lengths:
270-1086
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development