HsaINT0089853 @ hg19
Intron Retention
Gene
ENSG00000115919 | KYNU
Description
kynureninase [Source:HGNC Symbol;Acc:6469]
Coordinates
chr2:143635195-143643105:+
Coord C1 exon
chr2:143635195-143635305
Coord A exon
chr2:143635306-143642917
Coord C2 exon
chr2:143642918-143643105
Length
7612 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGC
5' ss Score
8.69
3' ss Seq
GTTTTATTATTCTCTTTCAGTTT
3' ss Score
10.5
Exon sequences
Seq C1 exon
GCAGTTCTTTGAATTTCTCACCCTAAGATCTGGCCTGTACATTTTCAAGGAATTCTTGAGAGGTTCTTGGAGAGATTCTGGGAGCCAAACACTCCATTGGGATCCTAGCTG
Seq A exon
GTAAGCTTGAGGCGCTGATAAAAACTCTCTACCCTAATGTTTACTCCATGTTTTTTCCAAATGAAACTTCTGTCAGCTAGAATCCTTGTCATAGTGTTTTAGAGGTTTTTTTCTGCTACTCTCTTCTTTTTTTATATATATTCTTTTTGTAAATAAAAATGGTATGACCTTCCTAAAGGCCCCACCTTTAGAAATGGGTTAAATGAAAAGATCTTTACTAATGTAATAGAAAAGAACTGATGAACATAGTGCACTGAATATGGTTACATTTGACAAACCAAAGTTAGTCCTGTTCTTATTTGAGTTTAAGCGGTAAGATTAGGTCAAACTCCAGACGAGGGAAAGATATTCTTAAACAGATTTTAAGTCCTCTGTTTTCTGGTAACTTTAATTGTCTTATGCTGCTAGTAGTCATATTAAATATTTATTTAGAGAAGTGAAAATGCCTACTCTTGAACAGAGTTTCTTCCCCTTTCATTTTATGAAACCTAAGAAAAGAAAGTTGATACACTTTTTAAAAATATACTAGATTTTCTTTTTTCCTTTCTGCTTTTATTTTGAGGCCAGTGGGGTGTTATTTAGTAGTAACACTGAAGCAAATGTATTGATTTTCTTAACGTGTTCAGCAAGTAATTCATATCCTAGATATGAAATATACACTCGTAGCAGAGTAATGTTACCCATTTCTCAATGATATGCTTAAAGAATCTTGCTCAATATGCATATTGTTTTTCCTTTTTTCTTTACTAATGAAAAACTACACGCTTTCTCAACATATTTTTAAGTCAGGTTCTAAACTTTGAACTCCTATGTACAATTTGCTTATTTCAGGCATGAATGTGAAACTGTGTAAAGATTAACTACCAGACACTCAGTCATTTATTTAACTATTTAGCCCTAAATCAGTGGGTGACTAGGAGATTCTGAATTCTGTGATTTCGTTAAAATCAATCAGTTTTTAATTATTATACAAGCTTTTTACTTTAAAGTTGTAGCTGTCTAAATAAAATTGTGAAAGCACAATTTCCAAACCTAAATCGAAGGCACATTGATGCTGTCCATCAGAAGGTATTGATAATTTAAAAAAATATTACAAACTATCTTTTATCTTTTTATAAAGGACCTAATGTCATTTGAGCTTAACCATAATCCTTTGAAGAAAGTAAAATTTAACTTTAAATAACATTGACATACAGAGCAGTTAGGTGATTTGTCTGAGACCATATGGTATGTATGTCCCCCGTCTTGATAAAATTAACACTAAATATGTAACATTTGAAAATTTGTAAAATATGTAAAAGTTGAAGTTTTTAAAAGTTTGGATTTAAGTTCTTCCTTTCAGAATATGAGCATGTCACTTTATTTGCAAACTAAACATGGCATAACATTATGGCTTGTGAACACTAATTGTCTTAGCTGCTGGGGTGAATGCAGAATTAAGCAGCAATTAGTATGAGTGAATAAATTGCATCCTTAGAGTGAGTGCACTATGCTATTCTGGGAACTAAAGACTATATTTGAGACCATGCGAAGTTGTGCAAGTGGTGGAGTAGGGCAGGGTGCAGTCATTTGGAAGACTATGCCCATCAGGTATCTCAAGGTACCCCAGATGTGACAGGCCCAGGAGCGGAACCAGCCACTTTAACTTTTGCCTGGCTGAAACTGGACTGGGAAGGATGGATTAAAAAGGTAAATCAATTCATACGTAGCTTGTGGTCCTTTGCAGCTTAAGTGTAGGACTGAAAAAAGAAGCCAAAGAAAAAGGGAATGAGCTGAAGAAATACACACACGTACACACACACATCAGGAAGCAACAGGCAAGGAAAAATAAAGTGAGAGGTTCAAGGCTTCGAGGAGGAATTGAGCTCTGTGCATTCCATTCATGGGCTTTGCCAAAGACCAGCACAATGGACTCAGCATCTCAGGCATGGTTAAGTACCCTACTGTGCACTCTGCTATCCTTTTAGTCCACTGGTTTCTACTCTGTCTGTGCCAGGTTTTCATCTCAATATAGAGGAAAAGGATTCTGATGCCTCAGGATTATTACAAGCATTAAATAAGATACAGATAGAATGACGCTAATGAGTATCATTTTTAAAATAAGGAAAGTTGAATTTTATTCAGAATCTGTTGGTAACAAACTAATCTCTTTATTTAAGTAACCCCACTTAGAGTTTAAAGTCACCTCCAATCAACTCAAAGGGCTGACCTCCCAAAGAAAGTCTCAAATATAAGGCAAGCTCTCTTGATTCTGAATTTCATTAGAAATGTTTGTCTAAGTCTTTCTCATATGGTCAGAATGAGAGAGGGTGCCCTTCTAGTAATATGTCATTATGTCAAATAATTCATCAACCAATTTTGTTTATTCTCTCGAACTGCCACTTTGGCGGCAGGGGTACTCTGTCTAAATGAGATGTCTATAAAGATAAATTAAACATGATTCAGGCCCCCAGGTAGAGTTCAGTTCAGTAGGGTAGAACAGCAACTCAGTCCAGCTACCATCAGTAATATGTTTGTAGTAAGACTAATCTGATAGTAAGGCAGAAAAACATCTCATGGAATTTTAGGAATAGCCAAGAAGATGGGTCCCCTGGAGACTTGCACATAGCATGTTGCATGAAGGATTCAGTGACTTGCAAGATGGGCTTGTCTTGTCACCTTTTCAGGAGACATAGCTGTTCAATCCCTTGCCATTGTGTAACTAAGTGACTCTTACTTGCTGCTGGAATCACTTCATGCTTTTCATGCTTTAACAATCAGTGGTTCTGTTTTACTTTGAAAAATGAGTCATTCTATGACAGTATTCCTCCTAGACCCTAGCATTTCATAGCTTCTATCTATGATTATTTTAAATTCTAGCTCCTGTATCTAACTGAATGAATAAGCACATCCCACAGCTCAGATTCCTGAAAGAATTTGATTATGTACTCAGCTAAACATCATCACTGTTTGGTTAGAGCTTTTATAGCAAATAATTCACAGATCTTTGATGAAACTACATTGTCTTTAGTGGGTAAGTGTCCAACAGAGGTCTAATAAACTATGACCAGGCAATTGATAATGCCAAGCGGTAGAGACACAGTGATCTCTCTTCAAAATGCAGTTTCCTTCATCAGAAAGCTATGTGTGGGGAGCCATTTAGAATCAAGTTTCAGGCATAGCAAATGTTTTTGATCTTTCCTATCCATACATATGTCCAAATAAATATAGTACCTGGCAGAATGTATTATTATCGTAAGTAAAGTACATAAGTGTGCTCTTAATTGTTATTGGTGTTCAGAGGAAGACGGGCTACTTTTGCCTGAGACATCCTAACAGGCCTCTTGAAAAAAGCATTGGAGCATTAGGTCTTTGAAGGTTGGCTAGAATCCAAACAAGTTGAAGGGGAGCAAAACATTTTAGGCAAAGGAAATGGCATGAGAAAAATCACAGAAATAGAAAATTTCATGTGGAGGACAAATAATACTTATGGTCAGATATTGAAAGCACCATCCATCAATGTTGAAATCCTACACTTTTGTACAGAACCATGGATTGAAGCAGTTAGGAGTCACAACTGATATCAAAGTAAAAAACATGCAATGGTGAACCTTGGTATCTTTGTCTAGGAATATAAAGAATGGCTTATCAGTGGAGACCATCGACAGTTGAGAAAAGAAGAAGCCCAAAAAGTACAAGAATGAAAATCGAGAGTGTAAGAAGAATGTCTGTTTTACTGGCATTATCTAACACTCAGATATGCAACTCTTTATTGCCAAACACTGTGTGTGTTAGTTAAGGTAAAAGGTGAAGGGAGGCAGAAGAATGGAGATTGAATTGAATTCTAGAGCTTTAGTTCTGTGTGAGTTTGGGCCCCCAGAAGTTCTAGACATTAAGTACAGTCTGAATTGAGAAATATTAAACATATCTTGTGATCCAATATTCCCCTAAGTTATACACTCAAATATCCAATGACCAGCTTGACATTTCTACCTGCATGTTCAATACTTATTTGAAACTTAATATATCCTAAATATAATTTTTTTTTAAACAGTCATGCTCTGTTGCCCAGGATGGAGTGCAGTGGCACAATTAGCTCACTGCAACCTCAGACTGCTGGTCTCCTACCCCATCCTCCTCGGTAGCTAGGACCACAGGTGCATGCCAGTGCCAGCACACCTGGCTTTTCTTTTCTTTTTTCTTTTTTTTTTTTTTTTTTTGTAGAGATGACATCTTGCTACGTTGTCCAGACTGGTCTCAAACTCCTGGCTTCAAGCAATCCCCTGCCTCGGCCTCCCAGTGCTGGGGTAACAGGTGTGAACCACCACAACCAGCCTGCTAAACTGAATTCCAATTTCCCTCCTCAAAATTTTTCTTCCCCAGGTATTTTTATTTCATCATATTTCACATATTTGCCCATATCCCAAAGCTAGAAGAAAGCTCCTTTCCTGTCCTCACTAGAAATAATCTATCCACCAGTCCTATCTACTTTTTCTCCAAACTACATCATAAATCCACACTCTTCTCTCTACCTTTGCCCTCATCACCAAATTTAATTCACCACCGTTTCTCTCCTGAACTACTGTGTTATCCTTAATCGGTCTCCCTTTTCAACTTTTTTTTTTTAATTATACTTTAAGTTCTAGGGTACATGTGCACAACGTGTAGGTTTGTTATATATGTATATATGTGCCATGTCAGTTTGCTGCACCCATTAACTCGTCATTTACATTACATATTTCTCCTACTGCTATTCCTCCCCCATCCCCCCACTCCACGACAGGCTCCGGTGTGTGATGTTCCCCGCCCTGTGTCCAAGTGTTCTCATTGTTCAGTTCCCACCTGTGAGTGAGAACATGTGGTGTTTGGTTTTCTGTCCTTGCGATAGTTTGCTCAGAATGATGGTTTCCAGCTTCATCCATGTTGCTGCAAAGGACATGAACTCATCCTTTTTTATGGCTGCATAGTATTCCATGGTGTATATGTGTCACATTTTCTTAATCCAGTCTATCATTGATGGACATTTGGGTTGGTTCCAAGTGTTTGCTATTGTGAATAGTGCTGCAATAAACATACATGTGCATGTGTCTTTATAGCAGCATGATTTATAATCCTTTGGGTATATATGCAGTAATGGGATTGCTGGGTCAAATGGTATTTCTGCTTCTAGATCCTTGAGGAATCACCACACTGTCTTCCACAATGGTTGAACTAGTTTACAGTCCCACCAACAGTGTAAAAGTGTTCCTGTTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTTTTAATGATCGCCATTCTAACCGACATGAGGTGGTATCTCACTGTTTTTAAAACTCATTACAGAGCTAAGTGGTTTTTATTTAATGTAAATTTATATCACATTACTTTTCTACTCAAAACTCCCCAATGGTATCCCATTAAACTTATAAAATTTCAGTTTTCTTTCTGGCTCCCAAATTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTCGCCCAGGCTGGAGTGCAGTGGTGCAACCTCGGCTCACTGCAGGCTCCACCCCCCGGGGTTCACGCCATTCTCCTGCCTCAGCTTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCTCGCACGGCTAATTTTTTTTTTGTATTTTTAGTAGAGACGGGGCTTCACCGTGTTAGCCAGGACGGTCTTGATCTCCTGACCTCGTGATCCGCCTGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCTGGCCCCAAATTTCTTTATGACTACCTTCTGCCTTTGTTTTTTGCATATCACAGTTTGTCATTCCTCCTTCCCTCTTTTTCCCTCCCTAGTGCATTTAGTTGAACAAGCCAAGCCCATTTCCACCCCAGGAACTTTGCACTTGTTGCCAGGTTCCTCCAGGTCCAGGTCTTCACATGATGTAGACATTCTCATCTATCACTTTCTCAGAAGGATGAACATGACCCTTTAAGGTAGCTCTTCCACACTCCAGTGACTCTGTCCCATTACTCTGCTGTTTCCTCATAGCTCTTAAGTCTGAAACTACATTGTTTTTCTATTCTTCATTTACAAATAAATTGTACAAGGGTTGGCACTTATGCACTCTCTCATACACTGCTGTCCTGCCATTACTGGGAGTCACATAATAGGTACCAAATAAATACTTGTTGAAAGAGTAAATAAATGTATAAATTAAATGAAATCAGCAAAACTATATGTAAATCTAACTAGCCCAAAGAAATTTTATTTCCTGTAATATCATTTTGTTCAAAAAACCAAACTTAGGAGAGGAGAAATATAAACAAACAAGCTTGGGTGAAGTTTAAAACGTATGTGATTAAATCTCCATTGTCATTTATCCTTTTCCAAAAAGTGGGAAATGTTGCATGATGATTAAACAGAATACAATGTGGTTTCAAGAAACATCACACAATCCTGTTTGTTCTAAGATAATAAATATGGTGTTGAAAGGAAGAAATTTATAATTACTAACAGCAGCAGGTGGATGAATCTCTTTGGTATTCATATGAACAAAATACTAACATTTTAAGTAAAGTTACCTTTTCCATGAATATGGTTTTCACTCACAAAAAAGGATTTTGTTCAGGTTCAATATGTCCATAGTTTTAAAACCATGATCCAAGAACCACTGGGGGTGGGACAGTGGAGTTGGGATATGGAGAAAGACAAGCTAAGTGGGATGCTGCTTTTCGACACTTTGACAAAGATCATCCTTACCATTATCTCCTCATAAGATACCTAGAGGAAAAGGTGATGACATTATATATATTTGGAAGCCACAAGTGTGGTACATATTTCTAGATAATAAGAATGGAATGAGCTAACATTTATTGGGAACTTACTCTGTCCTGAGCACTATTATCTAATTTAGTCCTTTCAATATCTCTAAGTTACTATTATTTTGTTTCTCTTTTCCTTTTTTTTTTTTTTTTTTTTTTTTGGTTTGTGTTTTGAGACAGGGTCTTGCTCTGTTACCCAGGCTGGAGTGCGGTGGTACAATCCCAGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGCGCCTGCCACCATGCCACCTTTTCCCAACCTCAGGAATAATATACTTAACCAACCAGCATTAAACTCCATGCATGAGTTTTTCTCATATATGAAAAGAAGAAAATAGGCCAAGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGAGCCATTTTTTGTATTTTTTTAGTAGAGATGAGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCTGGCCTATTTTCTTCTTTTCATATATGAGAAAAACTCATGCATGGAGTTTAATGCTGGTTGGTTAAGTATATTATTCCTGAGGTTGGGAAAAGGGAGTCTTAGTGAAAACAAAAGGTGTATTACCTAAAGGGCTCATTTTCTACAGGAAAATTATGGTGGCTAGATTATGTTTTATTATTCTCTTTCAG
Seq C2 exon
TTTTAGAGAACAACTTGTAATGGAGCCTTCATCTCTTGAGCTGCCGGCTGACACAGTGCAGCGCATTGCGGCTGAACTCAAATGCCACCCAACGGATGAGAGGGTGGCTCTCCACCTAGATGAGGAAGATAAGCTGAGGCACTTCAGGGAGTGCTTTTATATTCCCAAAATACAGGATCTGCCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115919-KYNU:NM_001032998:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.075
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
PF0318510=CaKB=PU(69.6=68.4)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)