HsaINT0096530 @ hg19
Intron Retention
Gene
ENSG00000162337 | LRP5
Description
low density lipoprotein receptor-related protein 5 [Source:HGNC Symbol;Acc:6697]
Coordinates
chr11:68170951-68174281:+
Coord C1 exon
chr11:68170951-68171167
Coord A exon
chr11:68171168-68173991
Coord C2 exon
chr11:68173992-68174281
Length
2824 bp
Sequences
Splice sites
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
3' ss Seq
GCCTCTGTGTTCGCTTCCAGGAA
3' ss Score
12.06
Exon sequences
Seq C1 exon
GTGATCAATGTTGATGGGACGAAGAGGCGGACCCTCCTGGAGGACAAGCTCCCGCACATTTTTGGGTTCACGCTGCTGGGGGACTTCATCTACTGGACTGACTGGCAGCGCCGCAGCATCGAGCGGGTGCACAAGGTCAAGGCCAGCCGGGACGTCATCATTGACCAGCTGCCCGACCTGATGGGGCTCAAAGCTGTGAATGTGGCCAAGGTCGTCG
Seq A exon
GTGAGTCCGGGGGGTCCCAAGCCATGGCTCAGCCATGCAGACTTGCATGAGGAGGAAGTGACGGGTCCATGCCTGGGCATAAGTGTTGAGCTCAGGTGCCCCGACCTGGGGAAGGGCAGGACAGGAAAGGTGACAGTATCTGGCCAAGGACAGATGGGAAGGGACCAAGGGAGCTGATTAGGGAGTGGTTATGGACTAGGAATGTCGGTAACAATGGTTAGAAAGTGACTAACATTTGTTGAGCACCTGCTGTGTGCCCGGCCCTGGCCGGGAGCCTTCGTGCCCACAGTGACCCCGTCTGCAAATGTAGTTCCTTGCCCTACTCGCACTGGGGAGCAGGACGCAGAGCCGTGCAACTCACAGGTGCCAAGCTCAGGACTCCCTCCTGGGTCTGCCTGGGCTGGGCTGTGCTTGTTGCCCCTGTGGCCCACGCATGTGCACCTTCCACCTGAAAGCCAGGATCTTCAGGACGCTCCCCGAGGAGGTCGTTGTCTGGCACAATGATTTGTCTCTTCCTGAAAAGGTGACAGAGTTACACTGGAGAGAGCAGCATCCAGGTGCGGCAGGGACAGGCCTGGGGCTCGCGGGCAGGGACTCTGTGTCCTGCCGGGGTCCCACACTGCACCTGCTTGTCAGAGGCACTCAGTCAATCTTTGCTGATGAAGGATGAGAGGACAGAGGACGTGATGCTTGCTGCTGCATTGCCTGCAGTCCTGGGTGAGATGCCCGGGTTGACTCTGCTGCCCGTCGGGTGGATGTGATGTCAGATCCCCGGCTTTAAAATACGAGGGAGCTGGGAATTGAGGGAGCAGGTTGGGGCAGAAAGCACAGCCCCGTGGAAGCCTGGAGCTGAGGCAGTGTGGGCGACCCCTGGAGCAGTGAGTGCTTCCTTCATGGCCTTCATCGCACCCTGCAGTCCTCATGTAGGGGATGCAATCCATGAATTTAGTTTTCCCAGCCTCCTTTAAAAACGCGTTCATGCTGGGGCCGGGGCAGTGCAGTGGCTCACATCTGAAATCCCACCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACAAGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGTGCGGTGGCAGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAAGCGGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCAGTCCGCAGTCCGGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAGTCCAAAAAAAAAAAAATTAGTCTGGGTGTGGTATCACGCGCCTATAATCTCACTACTCGAGAGGCTGAGGCGGAGAATTGCTTGAACCCAGGAGGTAGAGGTTGTAGTGAGCCCGTATCGTACCACTGCCCTCCACCTGGGCAATAGAGCGAGACTCTGTCTCAAAAAGAAAAAAAAAAAAAGAACATTTATGCCAGGTGTGGTGGCTCATGCCTGAAATCCCAGAACTTTGGAAGACTGAGGCAGGAGGATCACTTGAGCCCAGAAATTTGAGAGTGTCTTCCCTGGGCAACATAGAGAGACCTCATCTCTACCAGAAAAAAAAAAATTAGCCCGGCATGGTGGCATATCCCTGTGGTCCCAGCTACTTAGGGGGCTGACGTGGCAGGATCACCTGAGTCTGGAGGCAGAGGTTGAAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGTGACAGACAGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAGCATTTACTATCCACCATGGAAGGTGAGACTGACCTGTGAGTGATTGTTCAAAGAACAAAAAATAAACCCCAGAGATAAGACAAAAGGGTGCCTCCATGGGGGTGTGATTTAAAGCTGAGAAATTGGGCTTCTTCCCCCTCCCCTCTCACCCCGTGGTTTGCTAAAGGAGATGGGAAAAAGGATTCTTTTTTTGGCTGAAATATTTAACACTAAATTAAAGCCAATTTTAACAGCACTTTGGTTGATGAGTGAAATTAACAGACTGGCCAAAAATAAACGAACGGTCTGTACTATGTGAAAAAGAGGCAGCTTTGGCCATGCTGGGCCAATGTGAGTTTTCAGGGTTGCTGGGAATGTCTGTGAATCGGAGGAAGGGCCTAGCTGGGACTCTCAGGAGCCAAGGCCCTGAGGGGCAACTTGCCTGGTCCCTGCCCTGAGGCGTTCACTGCTTTCTTCCTGGGCCAGATCGCAGGCCCGGAGGCTGGACCACTGGGCTGGCACTCTTGCCGAGCTGCTCCCTGACTTCCTGACCATGCTCCTTTCAGCAGCCTTGCTGCACTTTAGTTTCCTTGAATGAAAAATGGGGATGAGAATAGCTCCTACCTCCAAGGTGAATGGAGTGAGTTCGGACAGGTGACTCCCTGGGACCAGTGCCTGGCGCCTGACAAGGTCCAGTCAGAGCCCGCACTGCTGTTACTGATACCCTTGGCTGTACCAGGGGAGAACTTGGTTGCCATTGCCAGGTGTTCTCCCACCACCCCCACTACTGTCCCTGTTTGATGTGTGGCGGGAATAAAGCTGTGCACATTGGAGCTTTTGGCACATCCTGGCTTTCAGGTGAAAGGTGCGTGTGTGTTTGAGGGTTTAGCCTGGCCAACCCAGCCATGAGGTCGGACCTGACCCGGGGGTGAGTCCTGAGCTCGGCACCCCTGAGCTGTGTGGCTCACGGCAGCATTCATTGTGTGGCTTGGCCGCACCCCTTTCCCTGCTGGGCTGTTGATGTTTAGACTGGAGCCTCTGTGTTCGCTTCCAG
Seq C2 exon
GAACCAACCCGTGTGCGGACAGGAACGGGGGGTGCAGCCACCTGTGCTTCTTCACACCCCACGCAACCCGGTGTGGCTGCCCCATCGGCCTGGAGCTGCTGAGTGACATGAAGACCTGCATCGTGCCTGAGGCCTTCTTGGTCTTCACCAGCAGAGCCGCCATCCACAGGATCTCCCTCGAGACCAATAACAACGACGTGGCCATCCCGCTCACGGGCGTCAAGGAGGCCTCAGCCCTGGACTTTGATGTGTCCAACAACCACATCTACTGGACAGACGTCAGCCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162337-LRP5:NM_002335:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(61.5=32.9)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=37.1),PF0005812=Ldl_recept_b=PU(24.4=10.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)