HsaINT0096530 @ hg38
Intron Retention
Gene
ENSG00000162337 | LRP5
Description
LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]
Coordinates
chr11:68403483-68406813:+
Coord C1 exon
chr11:68403483-68403699
Coord A exon
chr11:68403700-68406523
Coord C2 exon
chr11:68406524-68406813
Length
2824 bp
Sequences
Splice sites
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
3' ss Seq
GCCTCTGTGTTCGCTTCCAGGAA
3' ss Score
12.06
Exon sequences
Seq C1 exon
GTGATCAATGTTGATGGGACGAAGAGGCGGACCCTCCTGGAGGACAAGCTCCCGCACATTTTTGGGTTCACGCTGCTGGGGGACTTCATCTACTGGACTGACTGGCAGCGCCGCAGCATCGAGCGGGTGCACAAGGTCAAGGCCAGCCGGGACGTCATCATTGACCAGCTGCCCGACCTGATGGGGCTCAAAGCTGTGAATGTGGCCAAGGTCGTCG
Seq A exon
GTGAGTCCGGGGGGTCCCAAGCCATGGCTCAGCCATGCAGACTTGCATGAGGAGGAAGTGACGGGTCCATGCCTGGGCATAAGTGTTGAGCTCAGGTGCCCCGACCTGGGGAAGGGCAGGACAGGAAAGGTGACAGTATCTGGCCAAGGACAGATGGGAAGGGACCAAGGGAGCTGATTAGGGAGTGGTTATGGACTAGGAATGTCGGTAACAATGGTTAGAAAGTGACTAACATTTGTTGAGCACCTGCTGTGTGCCCGGCCCTGGCCGGGAGCCTTCGTGCCCACAGTGACCCCGTCTGCAAATGTAGTTCCTTGCCCTACTCGCACTGGGGAGCAGGACGCAGAGCCGTGCAACTCACAGGTGCCAAGCTCAGGACTCCCTCCTGGGTCTGCCTGGGCTGGGCTGTGCTTGTTGCCCCTGTGGCCCACGCATGTGCACCTTCCACCTGAAAGCCAGGATCTTCAGGACGCTCCCCGAGGAGGTCGTTGTCTGGCACAATGATTTGTCTCTTCCTGAAAAGGTGACAGAGTTACACTGGAGAGAGCAGCATCCAGGTGCGGCAGGGACAGGCCTGGGGCTCGCGGGCAGGGACTCTGTGTCCTGCCGGGGTCCCACACTGCACCTGCTTGTCAGAGGCACTCAGTCAATCTTTGCTGATGAAGGATGAGAGGACAGAGGACGTGATGCTTGCTGCTGCATTGCCTGCAGTCCTGGGTGAGATGCCCGGGTTGACTCTGCTGCCCGTCGGGTGGATGTGATGTCAGATCCCCGGCTTTAAAATACGAGGGAGCTGGGAATTGAGGGAGCAGGTTGGGGCAGAAAGCACAGCCCCGTGGAAGCCTGGAGCTGAGGCAGTGTGGGCGACCCCTGGAGCAGTGAGTGCTTCCTTCATGGCCTTCATCGCACCCTGCAGTCCTCATGTAGGGGATGCAATCCATGAATTTAGTTTTCCCAGCCTCCTTTAAAAACGCGTTCATGCTGGGGCCGGGGCAGTGCAGTGGCTCACATCTGAAATCCCACCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACAAGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGTGCGGTGGCAGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAAGCGGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCAGTCCGCAGTCCGGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAGTCCAAAAAAAAAAAAATTAGTCTGGGTGTGGTATCACGCGCCTATAATCTCACTACTCGAGAGGCTGAGGCGGAGAATTGCTTGAACCCAGGAGGTAGAGGTTGTAGTGAGCCCGTATCGTACCACTGCCCTCCACCTGGGCAATAGAGCGAGACTCTGTCTCAAAAAGAAAAAAAAAAAAAGAACATTTATGCCAGGTGTGGTGGCTCATGCCTGAAATCCCAGAACTTTGGAAGACTGAGGCAGGAGGATCACTTGAGCCCAGAAATTTGAGAGTGTCTTCCCTGGGCAACATAGAGAGACCTCATCTCTACCAGAAAAAAAAAAATTAGCCCGGCATGGTGGCATATCCCTGTGGTCCCAGCTACTTAGGGGGCTGACGTGGCAGGATCACCTGAGTCTGGAGGCAGAGGTTGAAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGTGACAGACAGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAGCATTTACTATCCACCATGGAAGGTGAGACTGACCTGTGAGTGATTGTTCAAAGAACAAAAAATAAACCCCAGAGATAAGACAAAAGGGTGCCTCCATGGGGGTGTGATTTAAAGCTGAGAAATTGGGCTTCTTCCCCCTCCCCTCTCACCCCGTGGTTTGCTAAAGGAGATGGGAAAAAGGATTCTTTTTTTGGCTGAAATATTTAACACTAAATTAAAGCCAATTTTAACAGCACTTTGGTTGATGAGTGAAATTAACAGACTGGCCAAAAATAAACGAACGGTCTGTACTATGTGAAAAAGAGGCAGCTTTGGCCATGCTGGGCCAATGTGAGTTTTCAGGGTTGCTGGGAATGTCTGTGAATCGGAGGAAGGGCCTAGCTGGGACTCTCAGGAGCCAAGGCCCTGAGGGGCAACTTGCCTGGTCCCTGCCCTGAGGCGTTCACTGCTTTCTTCCTGGGCCAGATCGCAGGCCCGGAGGCTGGACCACTGGGCTGGCACTCTTGCCGAGCTGCTCCCTGACTTCCTGACCATGCTCCTTTCAGCAGCCTTGCTGCACTTTAGTTTCCTTGAATGAAAAATGGGGATGAGAATAGCTCCTACCTCCAAGGTGAATGGAGTGAGTTCGGACAGGTGACTCCCTGGGACCAGTGCCTGGCGCCTGACAAGGTCCAGTCAGAGCCCGCACTGCTGTTACTGATACCCTTGGCTGTACCAGGGGAGAACTTGGTTGCCATTGCCAGGTGTTCTCCCACCACCCCCACTACTGTCCCTGTTTGATGTGTGGCGGGAATAAAGCTGTGCACATTGGAGCTTTTGGCACATCCTGGCTTTCAGGTGAAAGGTGCGTGTGTGTTTGAGGGTTTAGCCTGGCCAACCCAGCCATGAGGTCGGACCTGACCCGGGGGTGAGTCCTGAGCTCGGCACCCCTGAGCTGTGTGGCTCACGGCAGCATTCATTGTGTGGCTTGGCCGCACCCCTTTCCCTGCTGGGCTGTTGATGTTTAGACTGGAGCCTCTGTGTTCGCTTCCAG
Seq C2 exon
GAACCAACCCGTGTGCGGACAGGAACGGGGGGTGCAGCCACCTGTGCTTCTTCACACCCCACGCAACCCGGTGTGGCTGCCCCATCGGCCTGGAGCTGCTGAGTGACATGAAGACCTGCATCGTGCCTGAGGCCTTCTTGGTCTTCACCAGCAGAGCCGCCATCCACAGGATCTCCCTCGAGACCAATAACAACGACGTGGCCATCCCGCTCACGGGCGTCAAGGAGGCCTCAGCCCTGGACTTTGATGTGTCCAACAACCACATCTACTGGACAGACGTCAGCCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162337:ENST00000294304:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(61.5=32.9)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=37.1),PF0005812=Ldl_recept_b=PU(24.4=10.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development