HsaINT0097538 @ hg19
Intron Retention
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:6715]
Coordinates
chr14:74994050-74995401:-
Coord C1 exon
chr14:74995186-74995401
Coord A exon
chr14:74994070-74995185
Coord C2 exon
chr14:74994050-74994069
Length
1116 bp
Sequences
Splice sites
5' ss Seq
AGGGTATCT
5' ss Score
3.45
3' ss Seq
CTGTTACCTTTCCCTTCCAGGTG
3' ss Score
13.38
Exon sequences
Seq C1 exon
AGGCCTTCAGAGAGATCTGCCCTGCCGGCCACGGCTACACCTACGCGAGCTCCGACATCCGCCTGTCCATGAGGAAAGCCGAGGAGGAGGAACTGGCAAGGCCCCCAAGGGAGCAAGGGCAGAGGAGCAGCGGGGCACTGCCCGGGCCAGCAGAGAGGCAGCCCCTCCGGGTCGTCACGGACACCTGGCTTGAGGCCGGGACCATCCCTGACAAGG
Seq A exon
GTATCTGAGCTGGGGGAGATGCCTGAGGGATTTTCCTTTCCCCTAAGTTTCCAGCACCTCAGAGAAGTGTGGGTGTTAATCCTGGGTCCCTGGGCATCCCATCTCTGTGGCATTAGGAAAGGGAGCTTGGAGCAGCAGCACCCAACCCTGGCAGCCTTCTCTCATGGCCTGGCCCCACCCACTTCCTCTTCCATATGGGGTCAAGAGGTGCCCACGCCCCAGGGAGTTGCTTGTGGAGGTGGGAAAGATCAGCCGCAGCCCCCACCCCAGCGATCAGGCCTCTCCATCTCCTGCCCTCTGGCCATGCAGCTTCTGGGGCCGGTGCTTGCTGCAGGCCTGAATAGCTGGCAGGTGGGTCCTGGGGACCTGCATGTCAGACCCCTGGCCCGGCCTTGGAGTCAGAGTGCTAACTCCAGCTCAACGGCCTTGGACCCCAGAGGCACGGGGCTGGAGGGAGGCTGGGTATGAGGCTCTCCTTGCAAGTGCCCTGAAAACCATGGAGAAGTCATGCCCAGGTCACTGGTAACACTGAATGCAGGAGGCCTGGAACGTCATAGCGCCAGCAAACTATGTGATTGGTCAAACTGCTCCAGGAATCTGGAATAGACAGGGGAGTGAGGACAGAGCCCCAGTTGTTGTGGACACAGGACACCGGCCAAGCCAGGAGCAATTCCACTCCTTCCTCAAACTGTTCCCCTGGCCCAAAGCCCAGGGCAGGGGGCTGCATGACCCAGCCTGGCTGGGAGGCATGGGAGGGAGGAGGTAGCAGTGCAAGGAGGTGACTCCAGAATGGATGGGGTGGACAGGTCCGGGAGCAGGTGGGACTCCTGTCACCCGAGGCCTTACAGGAAAGCAGGGCCTTCCGCTTACCAAGTGAGAGGCTTCACTAAGCTATCTTCAGGCCCTCCAGACCTGGGGTTCTGGAATTTTGTGGTGGCCAGTCCCTACAGGGGTGATGGGGCAGAGGCAGGTAAGAAGAGTCCACGCTTTCTGTGCTGCTGGCCCTGCTGGGGATGTGGTCTGGGGCGCAGACTGTGAAGCCGCCCAGGTGGCGGTGAGGGGAGAAGGCAGCCAGACCCTCCTCCCTGAGCTCACGCTGTTACCTTTCCCTTCCAG
Seq C2 exon
GTGACTCTCAGGCTGGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681-LTBP2:NM_000428:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.671 A=NA C2=1.000
Domain overlap (PFAM):
C1:
PF0068312=TB=PD(11.6=6.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTTCAGAGAGATCTGCCCT
R:
CTGGCCAGCCTGAGAGTCA
Band lengths:
234-1350
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)