HsaINT0098962 @ hg38
Intron Retention
Gene
ENSG00000034152 | MAP2K3
Description
mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6843]
Coordinates
chr17:21305051-21312281:+
Coord C1 exon
chr17:21305051-21305128
Coord A exon
chr17:21305129-21312141
Coord C2 exon
chr17:21312142-21312281
Length
7013 bp
Sequences
Splice sites
5' ss Seq
ATGGTACTG
5' ss Score
4.16
3' ss Seq
ACCCCCTGTCCCCGCTGCAGATT
3' ss Score
9.56
Exon sequences
Seq C1 exon
CCTGAGAGGATCAACCCAGAGCTGAACCAGAAGGGCTACAATGTCAAGTCCGACGTCTGGAGCCTGGGCATCACCATG
Seq A exon
GTACTGTGGGGGGCCAGGGCCTGCCCTTGGTGGTCAGGTGGGGTGGGTGGAGCCGTGCCTGGGGCCCTGAGCTTTTGGGGGACTCATCAAATAGTTTAGGTTCTGGAAAGAAGTATTGGCTTCAAAATCTGAGAAGAAAATGTGCCATCAGAAATTACCATCTATTTAAGGGAACCTCCTAGGGTCAGGGTCACTCATCGTGAAGTCCTGGGTGCTTTGTGATATGGTGGCCACAGGGCTTTCTCTGGAGTTCTTGGTGCTTGTTGAGAAATCACAGCCAATCCCAAATTACGTAAGTTCCTGGTATGTAAATCATGCAAAAGCAAGATGGTAAAGATCTTTTCAAAAATATTTCATAGCAGAAGGTTTGTTGTCGGTGGCGTCCTGGTACATTGCGGTGGGGTGGTAGAAAGGGTGGGCGGGCTCTCAATCCTGGGCCTGTGGAAGCCAAAGGCATCCCTGGCTTGGGTAGGGTGAGGGCAGATGTGGCAGAAGTCCGAAGTCCAGGTGTAGGGATGGGCCCAGAGCAGTTGCTTCTGGAGTTGCCTGGCAGAACCCCATGCCTTCCGTGTTGGGGCTCAGGTCAAGGTGTGGGTGAGCCCGCTCTGGCTCCCCTGTGGACAGTGGATTGGAGGGATGGGAAGACCACCAGGATGTGTCCCCCAGCCAGGGCTAGGAAGCTGTGCAGGAGACGCGTGGAAGGACGATGCCATCAGCAGGTCGGGCTCAGGCTGGTGGCCTTGGCCAGTTGAGTGGCTTGGGACCAATGGAGTGTCCTGGGCGTCAGCTCCTTCCCTGCCCAGGGAAGCCTGGCCCAGGACATTCCTGCTTGTCCCTAGTCCCTTTGACTGTTTGGTGTTGGGGATGAGGCCGTCAGATAGAATCAGTAAGATGTGGTGAGAAGCGCTGGCGGGGTGTTTTCCAACACCGCAACCCATTCTCGGATTCTCCAGACACCCACCCAGTGCCCTGCAGTTCCGTTCGGTTCTGATGCTACCTGGAGTTCGCACAGACCCCACAGGTTAAGGGCTCTGTCCCACCAGACTGCCCCCAACATCACACACCAGTTGGAAGTAGCGGGTCTCCCATACTACTGGACTGACCAGCTACAAATTGGGGGTCCCCATGACCCTCTCGTAAGGTTTGATAATTTCCTAGAATGGCTCACAAAACTCAGGGAAACACTTTATTTGTGTTTACTGGTTTATCAGAAAGGATATAACTCAGGGCCAACCAGATGGAAGAGACTCACGGGGGAGGGGTGTGAGTGTGGGGTGCAGAGCTGCCGTGCCCTCTCAGGGCCTGGCACCCTCCTGGTACCTCCCTGTGCTTGCGAACCTACAGGCTTCTCAAGCTCATGGAATTTTGTTGTTTTTGACACAGAGTCTCACTTTGTCACCCAGGCTGGAATGCAGTGGCACAATCTTAGCTCACCGTAACCTCTGCCTCCTGGGTTCAAGCGATTCTTGTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCACCATGCCCAGCTGATTTTTGTATTTTTAGTGGAGATGGGGTTTTGCCATGTTGGCGAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTGCCCGCCTCAGACTCGCAAAGTGCTGTGATTACAGGCATGAGCCACCACGCCCAGCCTCACATGGAGAGGTTTTTTGTGAGAGAGGGTCTCACTCTGTTGCTCAGGCTGGAGTGCAGTGGTATCATCGCAGCTCACTGCAGCCTTGAACTCCCAGGCTCAAGCCATCCCCCTACCTCAGTCTCCTGAGTAGCTGGAACTACAGGTGTGTGCCCCTATGCCCAGCTACTTTTTTAATGTTTTGTAGAAAAGGGGTCTCACTATGTTGCCCAGGCTGGTCTTGAAATCCTGGGCTCAAGCAATCTGCCTACCTCGGCCTCCCAAAGTGCTGGGATTATAGGCACAAGCTACTGCACCCACTGAAAGTTTTTATAGAGCACAGTCTCCAGGCCCCCCTCCTCTCAGCATCAGTTGGCGGGTGATGCTGAGAGTTCCCACCCTCTATAATCAGCTGGGTTTTCTGGGGAGCAGCCCCATCTGAGGCTGTCTAGGGGCCTTACCCTGAGTCACCTCATTAGCATAAACTCAGGCTCCTTGTGGATAACAAAGCCACTCCTGTCACTCAGGAAATTCCAAGGGTTTTAGGAGCTCCATGCCAGGAACAAAGACCAAATAAATTCCTTTTTATGCCACGGGGGTGGAGAAGACTGGAGCAGGTAGGGGTGGCTCTGGGGACAGGTGGAAGGCCACTGTTGCAGATGCGGAGGCCTCTGCAAGGAGGGCACCCTGCTGACCTGAGGGCAGGGTAGACCAGGGGGTGCAAGTGCAAAGGCCCTGAGGTGGGGCTGTGCCTGCTGTGTGCCTGGGTGGCTGGGTCAGAGGAGAGGGAGGGAGGGTTGGGAGCGAGCGAAGAGAAGTGTCTGGTGGGTAGAGAGTTGACGCAGGTGTTGTGGGTTTTACTGGTGTTGCTGCTACCATTGTTATCATCATCATGTGGTTATAACTTTATTTATTTTTAATTTTTATTTTTTTGAGATGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAATGGGACGATCTCGGCTTACTGCAACCTCCGCCTCCTAGGTTCAAGTGATTCTCCTGTCTCAGCCTCCTGAGTAACTGGGATTACAGGCTCGTGCCACCATGCCCGGCTATCTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTGCACTCTGTTGCCTAGCCTGGAGTGCAATGGCATGATCTCAGCTCACTGCAACCTCTGCCTCTCGCGTTCAGGCAATTCTCCTGTCTCAGCCTCCCCAGTAGCTGGGATTATAGGCGTGAGCCACCACACCTGGCAAATTTTTGTATTTTTAAAAAAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCTGCCTGCCTCTGCCTCCCAAAGTGCTAGGATTACAGGGGTGAGCCACTGTGCCTGGCCTTTTTTTTTTTTGAGGGAGTCTCACTCTGTCGACCAGGCTAGAATGCAATGGCACAATCTCAGTTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCTTGCCTCAGCCTCTCAAGTAGCTAGGATTACAGGCATTTGCCACCATGCCCGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTTGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAACCACCACGCCCAGCCTTGAGCCACTGCGCCTGGCCTGTGGCTGTAACTTTATAAATAGTGTATCTGTAGACAGTGACTGGGAAAGACTCAAAGTCGAAATAATTTTGTCAGAGAGGTGGGACTGGGCCATACCTTCAATTTTCTTTAATTGGTGACATGTAATTTTTCAATTAAAATTTTTTTTTTTTGAGGTGGAGAGGAATATTCAGGCTGAAGGCAGGTGCTGTATCTGCAATAACAGTTTTCCAAGTCCTAAGTTTGATGCAAAGGACAAGTTCTTGCTGTATTTAGACTGCACAGAACTGGTTGGATATTAGAGACCCTGCTCATGACTACCTCACACATACACACACCCTATGTCCCTTCCCCATCTCCCTGTCTCCCTTCCAGTTGTCCATCCATCATGATTGTTGGGGCCACCATGGCTAGTGGCCTTCTGATATGGCTGGTGGAACTTGGACAAGTGTGTGCTAAGTGTATATTTCAGTTATCAAATATTGCATAGCAAACCACCCTAGAACCTAGTGACCCAAACCAACAGCGGTTTCTTATTTCTCATGTTTCCACCACTGTGGCTGGGCTCAGCTGGATGGCTCTTCTGCTGTACCTGGGATTGGCTGGGGTCATGGCTGGGCTGGGCTGGTCTGGAAGGCCCAAGACGGCCTCACAAACATGGGCCTCCTCTGCCTGGCCTCTCCATGCAACTTACTCACATTGGCCTGCTCCCTGGGCTTCAGAGCATGGCAGTGTCAGCAGAGTTGGAGTTCTTTCATGATGGCTGGCATCTAAAAGGAAGTTCTCTGAAGTGCTAGGCCTGGAACTGGCACAGCATCACTTCTGCCTCATTGTGTTGGTCAGCGAGTCACAGGCCAGCCCAGGTTCAAGGGCAGGGAATGCTCCCGGCTTAATGGAGGATCAGCAGGTGCACACAGCGGGAGGCGGAGGTGGTCACTTTAGGCACAGGTTAGGTTTTTCTTTCACAAGTTACAAACGTAGTGGAAACCTAACATAAAAATAGAGGCACAGTAAGGGGAAAATGACTGTAGTTATTCTACCTAGAGACACCTCTTACCCCGTTTCAGTGCCAACATTGTGCATTATATTATATATATAATATTTTTATTACATATAATAAAATACGTTTTATTAAAATTTAGAGAAATACAAACAATATGTAATGCTTCTCTTTTTTTGTTGTTGAAACAGAGCCTCGCTCTGTCACCCATGCTGGAGCGCGGTGGTGCGATCTCGGCTTACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGGCTCCCGAGTAGCTGGGACTACAGGCGTGCGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATATTGGCTAGGCAGGTCTCAAACTCGTGATCCACCCACCTTGGCCTTCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGCCTGGCCTCGTAATGCTTCTTTTTAAAAAACTTTTTAAAAAAAATTTTGTAGCATTACATGTTGTTCATATTTGTCTCTCTCTCTCTGTTTTTTTTGTTTTTTGTTTTTTTTGTTGTTTTTTTTTTTAGATGTAGTTTTGCTCTTGGTGCCCAGGCTGCAGTGCAGTGGTGCAATCTCGGCTCACCACAACCTCTGCCTCCTAGGTTCAAGTGATTCTCCTGCCTCACTCAATCTCCCAAGTAGCTGGGATTACAGGTGTGCACCACCACATCCAGCTAATTTTGTGTTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGACTGGTCTCGAACCCCCGACCTCAAGTGATCTGCCTGCCTCGGCCTCCCAAAGTGCTTGGATTATAGGTGTGAGCCACCGCACCTGGCCAATTTCTCTAAATTATAATAGACTCCTGTATGTATCCCTTCCAAAGACTCCATAACCATCTGCCACCATTCAGTCACCCTGTCTGCTGATGTGGGTTGTTTCCCTTGTTCCTGCTGTTTTCCTTCCATTTCAAATTCTCAGCCATCCTGGGGGAGCGACTGATGAAACAGAGTCGGGAGAGTCCCCCTGGGTGGGGCTCTGGCCTCGGCCTCCCCCCATCCTGCAAGGGCCCCAGAGCTCTCTTGGCGTTGGCTTTTTCCCACTCACTGCACAAGCCTCAGGATGCCAGTGGGAATCACCCAGAACAGACAGGGGTCATGCCGGGGATGGCCCTTGGCCAGGAGCAAGTGCTGACTGGGTGCTGGCCTGTTAGTGTTGTCGCTGGGGAGTCACAGGGGTGCGACTACGGTCCTGGCTGGGTCTCCGCCCCCATGGTGGGGCCGGCCCCTGGCGCTGGACATTCAGGCTGTTTCTTAGTATTTCCTGGCAGAAAACACCATATGGCACATCTTCGTGTCTGGAGGCTATTTTTGTTGTTTTTCATTTTTTGAGCTCTTTAGAAAAAATAAAGGAGTACGAGGTTGAAGGTTTGGACACTTCTGCTTTTCTAATTATAACTCTCATGGCCGCTGGTCCTTCTCCTGTAGCTCGTATGGGGTACTTGCTCTACATATTGCAGTCAGTGAAAATTCTAAGAGAAAAGCCCCCCAAATCGGTACGGTTTTGTCCTGTGAACACGCATGCACACATGCACACACACGCAGTGGGCCCTGCCTGTGTGGGTGTGTTTGTCTGAGCTGGAAAGGGCCTCTAGCCTGATGGGAGGCACAGTCTCAGCACAGTCCTTAGGGTCTTGTCCGGGCTCCAGTTGCCAGTGCCAAGTGTTTGTGCTGAGGTCTCTTCCGTTCATCATGGTGATGACGGCCGGCAGTGAGGGCCCTTGTGCTGGAGCCTCGGAATTCTCTGTTCTTCCAGGCCGGGGCCAGGGCTGACATAACTTGTTTTTTCCATCCAGTCATCATGATTGGAGCCCAGAGTTGGTTGTAAGCTAGCTAGTCCGTCCCTTCCATGATGACTTCCTGCCAACCACAGGGCTGGGAGCTTGGAGCGAGGACAGAGACCCACCGGCCCGATGTCACCCACAGGAAATCTGGATCCAGCAGGGCACATGTGGCCACACAGGCCACTTGTCTAGGAGGGAAACTGCTGGGGCCCTGCAGAAGATGAGGCTGCAGGCTCACGGGTGCAGAGGCGAAGCAGCCTCATGGTCTCACACTCTGTCCGCGGCCTTGGAGACAGCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGCATTTCCCATGTGCCTCCTCTGTGAAAACAGCCCAAATTAATGACAGCAGATGCTGAAGTCTGAGATGGTCAGATGTTAGGAAGGGGATTGGCTGTGACCACCTGGGACCTGCCCACCTGGCTCATGAGGCTACGGCCCAAAGTTGCCAGCTCCTCAGATTTTTCCAGAGCAGCTGGAACCTGCATTGTTTTGTAAAATCTTCAGAATTCAGGTTTTCTGAAAACCCTATGATGGTCCCACCAGTCCCGGTGTGGGCTGAATCTGCTTCCTGAGCTGGGTCCTGCTGGCTGGGTCGGAGGAGCTAAGAGCTGGCATCCCCGGCTTTCTCGCCTTTGTTCTGCTGGGATGTGGTAGGGAGATCAGCTGTGCAGCTTTGACGCCTGGCTCTGGTACCAGGATGGGTGGGAGCCCCCAACCCTCGCTCCTGGGTGCAGAGCGTGGTTGTATCTGGGGCCGGGGCCTCTGACCCCCTGTCCCCGCTGCAG
Seq C2 exon
ATTGAGATGGCCATCCTGCGGTTCCCTTACGAGTCCTGGGGGACCCCGTTCCAGCAGCTGAAGCAGGTGGTGGAGGAGCCGTCCCCCCAGCTCCCAGCCGACCGTTTCTCCCCCGAGTTTGTGGACTTCACTGCTCAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000034152:ENST00000342679:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.074
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(9.5=100)
A:
NA
C2:
PF0006920=Pkinase=FE(17.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development