HsaINT0099006 @ hg38
Intron Retention
Gene
ENSG00000076984 | MAP2K7
Description
mitogen-activated protein kinase kinase 7 [Source:HGNC Symbol;Acc:HGNC:6847]
Coordinates
chr19:7903843-7909896:+
Coord C1 exon
chr19:7903843-7904068
Coord A exon
chr19:7904069-7909754
Coord C2 exon
chr19:7909755-7909896
Length
5686 bp
Sequences
Splice sites
5' ss Seq
CCAGTAAGC
5' ss Score
5.34
3' ss Seq
ACTGGTTCTCACCCCCCTAGCCC
3' ss Score
7.89
Exon sequences
Seq C1 exon
CGGCGGCTCGACGGGGTCATCCGGGCGCAGGCGCAGTGCGGTGTTTGTCTGCCGGACTGACGGGCGGCCGGGCGGTGCGCGGCGGCGGTGGCGGCGGGGAAGATGGCGGCGTCCTCCCTGGAACAGAAGCTGTCCCGCCTGGAAGCAAAGCTGAAGCAGGAGAACCGGGAGGCCCGGCGGAGGATCGACCTCAACCTGGATATCAGCCCCCAGCGGCCCAGGCCCA
Seq A exon
GTAAGCACGGCGGCGTGGGGGAGGGGGCGGGCGGGCGGGGCGGGGCGCGCGCCGCGGGAGGCCCCGCCCCCACCACAAGGCCCCGCCCCCGCTTCCGGGGCGCTCGCTCTCCTCTCCGCCCCCCCCGCTGCGGGCTCGCGGGGCGAGGGTCACGGTGACCCGGGGGGCGTGGAGCCGGCGAGCTCCGGGGGGTTCGCACCCTCAGGGCTTGGGAGCCCAGTTCCCGGACCCAGGCGAGGCCCCCAGCTGATGACCCGCCCCCATCGCCGTGATCCTCTGGGTCGGGCTTCCCCGACTCCACGCGACAGTGACCACATCCAGGTCGCCCCGAAAACACAGACACGTCCCTGTTGACCTGATGCTACCACTCTCGTCATCTCAGGGACTGTCTGGCGCCCCCCTCCCCCGGCCTGGGGGCTTGTCAGCCCCGTGCAGCGACGATCTACGCACACGCGCACGCCTGGCTCGGGGACACCTGAGGTTACTTGACCACATAGAGCCCCTCCCCATCTCTTCTGACCCGAGGATTCTCCCTCTCGCTCTCCCTGTGACCGTGTCTGAGGTGGGGGGACGGGAGGGGGTCCCTTCTCCCCCTCTTGGCGACAGTGACCATGGCATTGGGCTCAGCAGACCCCCTCCCACATACACCAGGCCCCGCAAATCCCTGTGACCAGTTTCACTGCCACCATCTTGGTGAGCGTGTGGTGTCTGACCTCCAGAAATGCACATCGACCCCCAGCCAGCCCGGTGACTTTGTCACCTGTGTTCAAGTGATGGCTCCCCTTCCCTTCACACCCACACCCACCTGACCTGGGGACACCTGGGGCCAGTGTGACTCTAGGCCTGCTCCCGCCGCGCCCCAGCATACATCCACCTGCTTTCTGATCAGTCCCACCACCTCGGTACCTACCTCCCTGACACCTTGTCATCCTAGATCAGTACCTCTCGCTTCACACACACCTGGCCTGGGAACACTGACCATATCTAGTCTCCCGGCTTTTTCCCCAAGATCCTGGTCTCTAAATCCTCTGGGCTGGAGGAAATTAGATTTTCAAACCCTGTGAACACCACCCCTGACCCATGATCCTTTTTGTGTCTTTCTTGACCCAGTAAAATTCTCTCTTGTCTCCTCTGATGTGACCTTCGTAGTTTATTTAGTTCTCTCTATGGAGTCATTATGGCAGGCGAGAAAGGTACCCCCGTATCTGGGCACCCCACCCATTCCCTGGTCACCCAGCCTGACCTTCACAGCCTGACACCCTCCTGTCCCTCCCTCTCCTGACCTGAGTCAGCGTGGGTTCCTCCTTGGGGAGTCTCTTGGGGGTCCAGAGAAATCATGGAGGTGGGGATTCTGGTGCAGGACACTGCCTGAGACAAGAAGCCCAGCCAAGACACGGGTCCCTGCTAGCCCCTGGGGGCCGCCCTCCCTGGCCCCTGAGTGGATGAGACAGGGTTGAGTCCAGGATCCCGGGTGCCTTCAGGGGTGGCCGTTCCCATGCAGAGCTAGGAGGCCGGTGGCAGGCAGGCCCCCGAGGAGTCCCCTCCAGGCGTCTCTGTCTGTGTCAACTCCATCCCATCCTCCCCGCCCTCCCCATCTCTGTCGGTTCCTAGCCATCTCTGCAGTTCGGTGCCTCCCCCTCCTCCTCGTTTATGATTTGATTTCTTTTCTTTTGGACGAATCAGTCGTTTCTGTTGTGATTTATCGTGGTGTTGTTTTTTTCTTCCTTTTCCCCATCCAGTTATTGTGATCACTCTAAGCCCTGCTCCTGCCCCGTCCCAACGAGCAGGTACCAGCCTTTTTATCATCGCTGCTTGGACATCTGCACCATTGACCTAACCGCTGCCCCGGCCGCAGAATGGCGTCCCCCAGCCCCCATGCTCTGTGTGTGTCCCCATGTCCCTTCCCCTCACTCTCACTTTCTCTCTCACTCCACTCAAGCAGCGGTCAGCCCAGCCCAGCCTCCTCTGCGTCCTCCCTCCTCCTCCCCCTCCCTTACTCCCAGCTCCACTTTGGACTCCCTGGAGGAGGAGGTGGGCTCCCCCACTGAATGGGAGTCTGTGGCCTCCGGGGGTGGGGGGGGTGCACGCCTGTGTGTGTGTAACTGAGAGAACGAGAAAGTTGGGCCTGGTGGGTGGGTGGCCTGTGCCTATGGATCTCTCTCAACAACTAGGTGAACACATAGCACCCCCCGGGTTCCATACCAGCCCTGGGCGCCAGGGACACAGCAGTGAATAGAACAGATGGAGCCCCTCTCCTCTGTAGCGGGGGGCTGCAATAGGGGGGCCCACTGGACAAGGAGCACATTCCCACCAGAGAGAACATTCTAGCTGGGTGAGCGGCCCTGCAGGGGGCCAGCCTGGGGGAACCTCTGGAGACGGTGGGAATTGAACAAAGCCTCTGGGGAGGCCAGGCACGGTGGCTCACACCTGTGATCCCAACACTCGGGGAGGTTGAGGCTACAGGGAGCCATGATCACACCACTGCACCCCAGCCTGGGTGACAGCGAGATCCTGTCTCAAAAATTTAAAAACTGGGCCAGGCGCAGTGGCTCATGCCTGTAATTTCAGTACTTTGGGAGGCCAAGGAGGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTGCATTAAAAATACTAGAGATTAGGCCAGGCACAGTGACTCACACCTGTAATTCCAGCACTTTGGGAGACCGAGGCGGGTGGCTCACCTGAGGTCGGGAGTTCGAGACCACCCTGACCAACATAGAGAAACCCCGTCTCCACTAAAAATACAAAATTAGCCGGGCATGGTGGCACATACCTGTAATCCCAGCTACTCGGGAGGCTGTAATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAACCGCTTGAACCCGGGAGGCGGAGATTGCAGTGAGCTGAGATCGCACCATTGCACTTCAGCCTGGGCAACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAACATAAAAGATTAGGTGGAGGTTGCAGTGAGCTGAGATCGCGCCACTGCATTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAATTTAAAAAGCGTCTTGAAGGAGTTGGGGGGGGAGAGAAGACAGGGCCGCCAGGGCTCTGAGCGCAGCGCCAGCCTGTGTGGGGCATGCAGGCTGTGCCCCACGCCTGTGTTGGGAGAGAGAGTAGATGGGGTGCCTGGCCCTGTGAGTGGTTGTGAGTATGTGTGTCCGAGGGCAAGGGGGACTCTGTCCCGGCTGCATGGGTGTTAGGTCCACGGCATGCCCCGGGTGTGTGTTGTGCGTGCGTGCACTTGCACGGCATGTGCGTGCATGTTGACATGGCAGCCGGTGCACCTGTGGCTCCTGTCGGCAGACACGTGCCCTCCAGCCTCTCGCTCTCTCTCATCCGTTCTCTTTCTCATCCTCACCCTCTTGCTCTCACTCCACCCTCCTGAGCTGCCATGTGGCCATCACCACCTCTGTGGCCTCTGTTCTCAGGGCCTTTGTGTACCTCCTTCCCCCAGTGCCTACCTGAACCCTCCCTTCCATCCCCCCATGCTCCAGTCTGTGGTCCGGCAGCCTCCTCCCCAGGCTCCGGGGCCACCCTCGGAAGGCCTGGTGGGCTCTGTCAGGGAAGGGGCCCACAGGACTCCTCGAGGGCTGTGGTCGTCAACCGCTGAGTGCAGGGTGTGAGCGGGACTCGGATACTCTCTGAGGGCGGGAACTAGGCAGTGTCTCAAGAGATGCCAGGTGCACAGGGGTTGGGGGCTGGGTTGGGGGGAGCACAGGCCCTCGGGAGCCAGAAGGGGACTGGGGCTGTGGCTCAGGCCATGGACAGAGCAGAGGCGCAGGGACCTGAAGAAGCAGAGGGAGAAGCCTGGCCAACATAGCGAGACCCCATCTCTACTCAAAAGACAAAAATTAGCTGGGTGTGGTGGCGTGTACCTATAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGGGGATGTTGCAGTGAGTTGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGAACCTATCTCAAAAAAAAAAAAAAACAGTGGGAGGTGACGTGGTGCTGCAGAGGCGGCAGTGGCCAGGACAGCGGGAGGGGCACGGGAGGTGAGGCCTCTAGGCCAGTCATGAACGCTGGGCCTGGCTGTGTCCCAAGGTCCCCAGAGCCCTTCCCCTGCTCCTGCCTGGTCCTCCAGGAGGGGAGCTAGGGGGCACAGCTCCTGCAGGGGCTGGCAGGACCAGATAGGGGCAATGCTGGGCCTCCTGCATTGGGACTGAGGCGTCTTCCTGCCCCTCCTACTGGCTGAGATCAGGGTCCTGGGCACACGGGAGGGACGGGGTTTAGCTGCCAGCATGGAGCGGGTTTGTCTGTTCATATTAGTCCCTGGGCACCAGTCACCAGGAGCCTGCAGAACTGTGGGGAGAAAAGGTGGACGAGGCAGGAGGAAAAGAGGGGAGAGGGGCTTGTTGGCTGAGGGCTTTGGAGAGCGGCAGGCCCCAGCTCCTGTGGGAGGGGCACCTTGGTAGGTGTGTGTAGCCGTTGTCAGGGCCTCTAGGATGTGACGTGTCAGGATTGGCTCCTCTGGAGGCCACGTTAGCATCCCGGCCTCTGTTCCTGCACCCTGTTGCCAGCCCAGCCAGGGAGACCCTAGCTCCTCCGGGAAGCTGCCCTCCTGTCCCAGGCCCCTCTCTGGCCTGTCTCTGCAGCGCCTCCTCTGGGCACCTGGGCCCTAGTCTTGGTTCCTGTCTGTCTGTCTGTCTCCTGCCCTCCCACCCCTAATGCCGCCTGCCCACCCCAGGGTGCCTGCTGCCTGCCCGCCGCCTGCCCACCCGCTGTAGCATGCCCGAGCTGCCCGCATGCAGGCTGCTGGATGAGCCAACCCCCGCCTGGCCCAGCATTGGCCCCACCTGGTCCCGCCAGCCCCTGCAGGAGCTGTGCCCCCGAGCTCTCCTCCCAGAGGATGCAGGCCCCCTGAGGTCCTGTCCTGCCCCCATGGGCCCCAGCTCTGCAGGCCAGGCCAGGAGGCCCTCATGTCAGCCCACTGGCCCGAGGGGGGCCCTCCCTGACCCCGGAACAGAAGATAGGGCAAGGCAGCCTGAAGCCTGGGTCTCGTGCCCGCTGCCTCCCCAGCGTGGCCCTGCTCGCTCTTGTCTGGGAGCCAACTTCAGTGCTACCAGCAGAGCCACAGCCTGGGCCAGCCCTGGCAGGCACTCCGCCCTGGCCTATCCATCCTGTGGGTGCTGTGGCCCTGGGCCTGCTTCCTGGGCAGAAGTGGGAGGAAGTGCACACACCTGTCAGGGAGGCCCCCTGGCCGAGGGACACCTCAGGTCCCCATCTCGTTTCTCCGTCAGCGTAGACTTGGGGCTCCCTCTCCCCTGCTAGCCTCCTCCATCTCTTTCCAGGTCAGGGGATGAGACAAGGGACCCTGAGAACAGTCTGGGGTGGGAGGGAGACCCCAGCTCCTCCAGCCCAGCAGGGCAGGGGGCTGTGCCAGCCTAGCTCGGGAAACCCAGGAGGGGAAGGTGAGGGTCCCGACCCCTCCCTGGAGTGCCAGATGTGGAGCTGACACCAGCTGGGCGCTGACCCCCCTCCCTGCCACTGGTTCTCACCCCCCTAG
Seq C2 exon
CCCTGCAGCTCCCGCTGGCCAACGATGGGGGCAGCCGCTCGCCATCCTCAGAGAGCTCCCCGCAGCACCCCACGCCCCCCGCCCGGCCCCGCCACATGCTGGGGCTCCCGTCAACCCTGTTCACACCCCGCAGCATGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000076984:ENST00000397981:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.979 A=NA C2=0.865
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development