HsaINT0099014 @ hg19
Intron Retention
Gene
ENSG00000076984 | MAP2K7
Description
mitogen-activated protein kinase kinase 7 [Source:HGNC Symbol;Acc:6847]
Coordinates
chr19:7976135-7976463:+
Coord C1 exon
chr19:7976135-7976215
Coord A exon
chr19:7976216-7976320
Coord C2 exon
chr19:7976321-7976463
Length
105 bp
Sequences
Splice sites
5' ss Seq
TTGGTGAGT
5' ss Score
9.27
3' ss Seq
CCTGCCCGTCTCCCTCCCAGGTG
3' ss Score
11.47
Exon sequences
Seq C1 exon
CCCGAGCGCATTGACCCCCCAGACCCCACCAAGCCGGACTATGACATCCGGGCCGACGTATGGAGCCTGGGCATCTCGTTG
Seq A exon
GTGAGTTGGGGCCCTCCCCTGTTCTCCAGCCAGGAGTGAGGGCTTCTGGGGGACTCGGAGGGAGGAGAACATAAACCTGTCCAGCCCTGCCCGTCTCCCTCCCAG
Seq C2 exon
GTGGAGCTGGCAACAGGACAGTTTCCCTACAAGAACTGCAAGACGGACTTTGAGGTCCTCACCAAAGTCCTACAGGAAGAGCCCCCGCTTCTGCCCGGACACATGGGCTTCTCGGGGGACTTCCAGTCCTTCGTCAAAGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000076984-MAP2K7:NM_145185:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.148 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(10.0=100)
A:
NA
C2:
PF0006920=Pkinase=FE(18.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCCCAGACCCCACCAAG
R:
CAGTCTTTGACGAAGGACTGGA
Band lengths:
209-314
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)