HsaINT0099014 @ hg38
Intron Retention
Gene
ENSG00000076984 | MAP2K7
Description
mitogen-activated protein kinase kinase 7 [Source:HGNC Symbol;Acc:HGNC:6847]
Coordinates
chr19:7911250-7911578:+
Coord C1 exon
chr19:7911250-7911330
Coord A exon
chr19:7911331-7911414
Coord C2 exon
chr19:7911415-7911578
Length
84 bp
Sequences
Splice sites
5' ss Seq
TTGGTGAGT
5' ss Score
9.27
3' ss Seq
GAGAACATAAACCTGTCCAGCCC
3' ss Score
-0.22
Exon sequences
Seq C1 exon
CCCGAGCGCATTGACCCCCCAGACCCCACCAAGCCGGACTATGACATCCGGGCCGACGTATGGAGCCTGGGCATCTCGTTG
Seq A exon
GTGAGTTGGGGCCCTCCCCTGTTCTCCAGCCAGGAGTGAGGGCTTCTGGGGGACTCGGAGGGAGGAGAACATAAACCTGTCCAG
Seq C2 exon
CCCTGCCCGTCTCCCTCCCAGGTGGAGCTGGCAACAGGACAGTTTCCCTACAAGAACTGCAAGACGGACTTTGAGGTCCTCACCAAAGTCCTACAGGAAGAGCCCCCGCTTCTGCCCGGACACATGGGCTTCTCGGGGGACTTCCAGTCCTTCGTCAAAGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000076984:ENST00000397981:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.160 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(10.0=100)
A:
NA
C2:
PF0006920=Pkinase=FE(20.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATGGAGCCTGGGCATCTCG
R:
GACTGGAAGTCCCCCGAGAAG
Band lengths:
172-256
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development