HsaINT0099914 @ hg19
Intron Retention
Gene
ENSG00000136536 | MARCH7
Description
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:17393]
Coordinates
chr2:160604316-160609082:+
Coord C1 exon
chr2:160604316-160605414
Coord A exon
chr2:160605415-160608912
Coord C2 exon
chr2:160608913-160609082
Length
3498 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAAT
5' ss Score
8.39
3' ss Seq
AAATGTGCCTTCTTTTCCAGCCT
3' ss Score
7.67
Exon sequences
Seq C1 exon
ATGTTCAAGACAGAGTTCCTTCATATTCACAAGGAGCAAGACCAAAAGAAAACTCAATGAGCACTTTACAGTTGAATACATCATCCACAAACCACCAATTGCCTTCTGAACATCAGACCATACTAAGTTCTAGGGACTCCAGAAATTCTTTAAGATCAAATTTTTCTTCAAGAGAATCAGAATCTTCCCGAAGCAATACGCAGCCTGGATTTTCTTACAGTTCAAGTAGAGATGAAGCCCCAATCATAAGCAATTCAGAAAGGGTTGTTTCATCTCAAAGACCATTTCAAGAATCTTCTGACAATGAAGGTAGGCGGACAACGAGGAGATTGCTGTCACGCATAGCTTCTAGCATGTCATCTACTTTTTTTTCACGAAGATCTAGTCAGGATTCCTTGAATACAAGATCATTGAATTCTGAAAATTCTTACGTTTCTCCAAGAATCTTGACAGCTTCACAGTCCCGTAGTAATGTACCATCAGCTTCTGAAGTTCCCGATAATAGGGCATCTGAAGCTTCTCAGGGATTTCGATTTCTTAGGCGAAGATGGGGTTTGTCATCTCTTAGCCACAATCATAGCTCTGAGTCAGATTCAGAAAATTTTAACCAAGAATCTGAAGGTAGAAATACAGGACCATGGTTATCTTCCTCACTTAGAAATAGATGCACACCTTTGTTCTCTAGAAGGAGGCGAGAGGGAAGAGATGAATCTTCAAGGATACCTACCTCTGATACATCATCTAGATCTCATATTTTTAGAAGAGAATCAAATGAAGTGGTTCACCTTGAAGCACAGAATGATCCTCTTGGAGCTGCTGCCAACAGACCACAAGCATCTGCAGCATCAAGCAGTGCCACAACAGGTGGCTCTACATCAGATTCGGCTCAAGGTGGAAGAAATACAGGAATATCAGGGATTCTTCCTGGTTCCTTATTCCGGTTTGCAGTCCCTCCAGCACTTGGGAGTAATTTGACCGACAATGTCATGATCACAGTAGATATTATTCCTTCAGGTTGGAATTCAGCTGATGGTAAAAGTGATAAAACTAAAAGTGCGCCTTCAAGAGATCCAGAAAGATTGCAGAAAATAAAAGAGAG
Seq A exon
GTAAATTCGAATACCTGTCTTAAGCCTATAAATCAAAAATAGAGAAAGAACTCTTCATTTCTTTTTTTTCTTTTCTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCAGTCTGTCACCCAGGCTGGAGTGTAATGGCACCATCTCGGCTCACTGCAGCCTCGGCCTTCCAGGTTCAAGCAGTTCTCCTGTTTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCACTCCACCACACGTGGCTAATTTTAGAATTTTAGTAGGGACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTTAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCCAGCCTAAAACTCTTCATTTCAAAATTGGCTTCTTATAAAATTGAAATCTGAAGGGTTGTTTTGTTTTTGTTTTTTTTTGTTGTTGTTGTTGTTGTTGAGATGGAGTCTCTGTTGCCCAGGTTGGAGTGCAGTGGCACAGTCTTGGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCCTGCCACCATACCTGGCTAATTTTTGTATTTTTAGTAGAGGCAGGGTTTCACCACATTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAATGATCCACCTGCCTCCACCTCTCAAAGTACTGGGATTACAGGCATGAGTCACTACTTCCAGCAGGAAATTTCATCCCTTTACATCCAGTAAGATGTTTCATTCATAGGTAAATAGATAAGAATTAATAACTGAAGGTAGGCAATGGTTGGGGCGGGGGGGGCGGTTGTGAATTGTGTCAGAAAGTAAAGGTTATTTTAACCGGGTTGGAATACATATACATGCAAAGACAAAAACCTTAATGTCTTACCCAATTCCTTAGTAGACTAATGCTAAATGGGGTTAGTAAGAGGAACTGGATGACCATGGATTACCAATAAATCTGTCTTAGCCTTTATTAAGATGATTTATTAACCATTTATTTACATTTCTCACTGCAAATCTTTTTTTGGAATTTGATGCACAAAATTTACTTTGATTCACAAGATAAAATTTGATGCACAAAATAATTTTTGTGTTTGAAGTCCAAGTATATACTGAATATTCTCTTTCTTTAAACTTTTTGTAGAGACAGGGTCTCGCTTTGCTTCCCATGCTGGTCTCAAACTCCTGGCTTCAAGCGATCCTCATGCTTCAGCCTCCAAAAGTGCTGAAATTACAGGCATGAGCCACCATGCCCAGCCAGTTCTTTAGATATTAGTATTTAACAGAGATACCAGTTTAGGCCGGGCGCAGTGGTTCACGCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCACAAGGTCAGGAGATTGAGACCATCCTGGCTAACATGCTGAAACCCTGTCTCTATTAAAAATACAAAATTTAGCTGGGTGTGGTGGCATGCACCTGTAGTCGCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGATTGCACCACTGCACTCCAACCAGGCGACAGAGCAAGACTCTGTCTCAAAATAAAATAAAATAAAATAAAATAACAGTTTAAATGCAGGGCATAGAATCTTTTTATACAAAGAAATCTTTATAGAGTTGAAGGTTGCTTATAAATCACTGTTAAGAGTGAAAAGACAAAAAAACAGAGATCTTAGTCCCAGCCTGACTCTTAATTTAGTCATCCTAGTCTAATTACTTAGTATTAAAATAGTTATTAAAATGAGATAAATTAGTTTATTTGAAATACACTTGGAGGAAGAAAAGACTTATATAAAGTTAATGTTGTGGGATTTTTTTTTTCTTTTTCACAAAGGCCTAATAGAATTGTTGGGAAGCATAATTGTTACTGTTATTTTTAGATTTTTTTGTACTTTAATAAGAAAATACTTTCAAATCCAACTCTGGTGATAAAGGAAACTCTGCACACTTTCTGAGATGTTGGGCATTGGGCTACCATACTCCTATTTTTCATTTTATAGGACAGATTTTACCATGTGGCTGTTATTTTCCTGCTTTTAAACTTGCTATTTTTCCTTTTTTGTAGAAAGAGATTTACTCTACCCTGGTAGTGTTTGCTTTAATGTTTGCTTGTTACAGCAGCTTCCTCCAATTGCAGGCTGTCTGCTGTCTGCTAAGGGATGTAGTAACATATTTTCAGCCCTTAAGGTTAGATTAATTTAAGTACAGTAGTGTAGGCAGAGAGCAAAGCGTTACTTTAGTTATCTTCAGAGAGAAATGATTGAGCCAGTACCACTCTATCTGGTTAATTAAAAAGCAGCATTTGGTTATTTTGCCAGAGAGAGTGTGTGTGTATGTTTGTATTTCTGTATTACATCTTTCCTCATACCTAAGGATTTTAAGACATTCTACAATTAAAAATGGTACAGAAAAATTGAATCCACCAAGTGAATAGTTGAAACCAGGAAGGGAAGAAAGTTAAAGGTAAAATGTAAATACCATGTTTTCAATCTTTAAAAATAATTTATGCTTGAGGTTATGTCTGATTAACCCAGGGCATGAAAGTCTCCTAGCGGCTGTATATCCATCTCTTTTCACAAATCTTTTGCTAAGTTCATTTAGGAATCCATGTATTCCAGGTTGTATTTCAGTAACAGTTCAGCATTCTGTATTACCAATTTACTGTATACCTGTTTCATGCCAACAGTGGACTAACGCAGTAGGAATTTTAACAACTACTTACCTTATTATATAAAACTATTACTCTGCATTTATATATTAAGCAGTACACAATGGCCTGTTAAATAGAGGACGTAGGTTAATGGAATCTTTTATAAGATTGCTGCGCCGAGGGGGCAGATGGAGAATTTTAAAGCATTCTTTCAAATTTTTTTCTGTAATACAAAAGTTTATCAGTTTAAACATGGTTCTGGTAACATGTAAATGAGAATCTACAAGCCAGTATGTGTTTAATTCATGGAAGTAGCCCTAAAATTTGAGGGGAGGCAAGGGGCAAAAGTGATAAGTTTATCTTACCTTTATACTGTTGGACTTGAAGTAGTCTGGAATACTACAGAAATTAAAATCTCTTAGGGGTACTTGTAAAGTCATTGAGAAAAATATAGATCTTAAACTGTCATTTGCCAATGACAAAATTACTTAAATCATTTGAAAATAAATGATAGGTTAGCCTATTTTACTTACCTTTAAAATACTTGTTACAATTTTTATTCTCAATGAGAGAGTTTTTCATTTTCAATCAGAGGGTTGCTGATGAATATAATTGTTATTGTTTTGTTGTTGTTACTGTTTGCTTTTTTCCACCCAGAGACAGTGTGAGTAGAAATAACAAAAAAGAAAGCTTGTGATTATGTATGACTGAAGTAACCAACCAGGATGAGTTATGATAGCTTTGGGAAATGTGCCTTCTTTTCCAG
Seq C2 exon
CCTCCTTTTAGAGGACTCAGAAGAAGAAGAAGGTGACTTATGTAGAATTTGTCAAATGGCAGCTGCATCATCATCTAATTTGCTGATAGAGCCATGCAAGTGCACAGGAAGTTTGCAGTATGTCCACCAAGACTGTATGAAAAAGTGGTTACAGGCCAAAATTAACTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136536-MARCH7:NM_022826:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.807 A=NA C2=0.049
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF129062=RINGv=PU(76.8=74.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)