HsaINT0101575 @ hg19
Intron Retention
Gene
ENSG00000148297 | MED22
Description
mediator complex subunit 22 [Source:HGNC Symbol;Acc:11477]
Coordinates
chr9:136207755-136211188:-
Coord C1 exon
chr9:136210980-136211188
Coord A exon
chr9:136208545-136210979
Coord C2 exon
chr9:136207755-136208544
Length
2435 bp
Sequences
Splice sites
5' ss Seq
CAGGTATAA
5' ss Score
7.46
3' ss Seq
GGTTTCTGGTGGTGGAAAAGCTC
3' ss Score
-1.94
Exon sequences
Seq C1 exon
GTCCGAGCCGGCGAGTCCCTGATGAAGCTGGTGTCCGACCTCAAGCAGTTCCTGATCCTCAATGACTTCCCCTCCGTGAACGAGGCCATTGACCAGCGCAACCAGCAGCTGCGCACACTGCAGGAGGAGTGCGACCGGAAGCTCATCACGCTGCGAGACGAGATCTCCATTGACCTCTACGAGCTGGAGGAGGAGTATTACTCGTCCAG
Seq A exon
GTATAAATAGCGCTGGACTCCCCATGCAGAGCGGGAGCCTGCCTACCTGGGCCTGGCCAGCAGGCAGGGCTGCCTTCTGCTTTTTCAAATTCTTGCTGGTCTTAGCAGTGGAGCCATGCCTGGGTTTCAGAGCAGAGCTCCTGGCCAGAGCGTTTGACCGACAGACAATTCACATCCATATGCCAGGGCCCTGGGCCTTTCCCACAGTGCAATGTGATGAAAACCACAGGACTCACGCCAGTCGGATAGGCCGAGTCTGGAGAAGGGAGGCGCCTGGCTGTATCCCCCGCAGGCCCTCTTCCGAGAGCCTTCCTCCTCGGGCAGTGCGTTCTGGGGCTGTGCTGCTCCTGTTACCTTCTGAATCCATATGTAGAGATTTCAGCCAAGGCTGGGCCAGCCTTTTTTGGGCAGTCAGGTCCACACCTATGTCCAGGGCACCAGGGATGCAATTCCATGTGGATGTCACCAAACCCCAGTGTGGAGGCAGGGACAGTCATGGGAATGTGGGGGATGAAGCCCAGGCAGGGAATGGCCTTGAAAGCCATTGGAGCTCCAATTCGTGACCCACTCAGCCTTATCCACGGAGCTGGAGCCAACCTACGTGCCAGGCCCCATGCTGGGTCCCAGGGATGCAGAAGGGTCAAAACCCATCATCCTGACCCTTGTGGGGCTCCGTAAGAAGCTGAAACCTTCGACCGTTTGAGCTGGAGGGGCCCTGAGAAATCAGAGTCTACGTATCATTTACTTAGGGGGAAACTTAGGCTGGAGACAGGGAGGCCTTCCACTCTGCCCCATTAGCTTAGAAAATCAAGATTCAGTCCAGCAGATGCAGAGTCCATGTCCATCTTGTGCCTTCTCCTGGACAAACCTTTCCTTCCTGGTGGTGGATTTAAAATACTCCTTTCTGCCCATTGGCCATGCTGGGAGCCACAGCTATCCAGAGCCAGCATGACCTGGGGCTTGGTTTCCCTGCCCTGGGCTCAGTGGCACTGCTGAGCTGCAGCAGTCCTAGAGTTTTCCAGGGGGTTCTGAGGGAATCTTTGGTCCCCAGTACTCATTAACTCAGCAGACATGAGGCAGCATTTCCTCCACACTAGGGTGGCTGAGAGGGGTCCTGGGGTGTTTCAGACCCTTCTGGGCATCTCCTTCCACAGCTGTTCAGTTTGTCGGTCTCTTTGAGGCAGCCACCGTCCCTGAGGGCCCCTGCACAGAGCAGCTGTGGGCCTGTAATTCAGCCTGCCTGCCTTGCCTTGGGGCAGGGAGAGAGGGAACCTGCTCACGGCCCTGCAGCAGAGCAGGGCGCAAACCCAGGACATCTGTGCCAGGCTTCCCATGCCCTCCCCCAACAGTCCCTCAGCTTCACCCAGCGGGGCTTCCAGGCCAGCCTGTGTCCCCTCCCGCAGGCCTCCTGTCCACACCAGCGCCCCCTGGGGGGCCTCACACAGCCCCTGTGGCAGAAGCAGTTGCCCTCCTCTGTACATTGCCTTTAAGCGACCAGGTCCTGGCCGAGTTTCCTCTGCCCCTTCTTGCTGGTCCCCCAAAGGGCGCTCCGCTCCCTGCCCTGCCCTGCCCTGCCCTGTTCCGCATGAGCTGCGCCTCTGTGCTCGCCTGCCCCCTCTCTGCTTGTTAGTTGCTCTTTCTGGCTCTGCCTCTCCTTTGCTTTCCTCGGGATGCCACTCTGTGCCCAGGACGGTTCTGAGACTGAACACTGAGGGCAGGAGCAAGGGAGGAAGCCAGGGGCGAGGCAGGCCGCGGGAAAGCCAGGGCCCCTGCCTGCAGGTTAGAAAGAGGCGAGCGTGGATTGTCACAGCTGCGGGCATGGGAAGGGCTAGCTGAGCTCTTCACCTGCATCCTGGCTGCCGTGAGGATTCCCCGTGTTAGAGGTGGGGACGCCTGCTGGAGGCCGCCTGGCTGATGTAGGGCTATCGGGAAGTGCCAGGGCCTGTGTTCCCAACTGTCGCCCCCTTCAGGCTAAGTCTCAGGCAGGGACAGACCCAGAAAGAACACAGTCTGCCCTCAGAGAGCTCTTTGCAGTGTAGTGACACTGGGGTTTCTGCAGTCAGGGAGGAGGGAGGGTGGCCAGGCTGACAGCTTTTTGCAAGAGGAGGGGGACCAGCACCAGCTGGGAGGCATAGGCTAGGACAGGCCCACGTGGAGGCTGGGCAGGAAGGGCCTGCTGAGGTCACACAGCTGTTGGTGGTTGGGCCAGGGCGGCTTCCTCCTTTCAGAATGCTAGGGTGGCTCTCACCACTGGCCGCCTCTCCTTGCCAGGCCTGCCAACTCAGGGGACAGATGGAGCAGGAGTGGAGAAAGGGAAAGGCAGGTCTGGGGTGTGGTCGTGTTTTCTTAACTCTGCTTCTGTCTTGCTCTCCCCTCCCCTGGCTTTCCTCTCTGCCTGCTCCTGTCTCTCCCTGGGGTTTCTGGTGGTGGAAAAG
Seq C2 exon
CTCAAGCCTTTGCGAAGCTAATGACCTGCCTCTGTGCGAAGCTTACGGGAGGCTGGACCTCGACACAGACTCTGCTGATGGCCTCTCGGCCCCTCTGCTGGCGTCCCCGGAGCCCAGTGCTGGCCCCCTACAGGTGGCAGCCCCTGCCCACTCCCATGCTGGTGGCCCTGGCCCCACTGAGCACGCCTGAGCCTCCGGGGCCACGCTTCGTTCTCAGGAACAAAACCTGAGGCAGCCCTTTGGATGCCCTCACAGCCTTGCTTCTCTCAGCCTAGGTTCCCATTTGGGGACTTCAGGACCCCAGAGCCACTAGGACTTCCTTGGGAAGCCCGTTAGCCCAGGGTGGGTCCCACCAGGACAGTAGGGAAACAGTTGTTTCCCTAGCCATTTCCGAATAGCCCATCATTCCGAGTCATCATCTCTGTTTGCTGCCTTCCTGGCCAGCCAGGTGGAAGAAAGTTTCCAAGCTAGGTCTGGCCCGTTGGGGATCTCAGCAGTGGGGCAGGAGGGTGCCTGATTTCGGGGAGTCCTGACCCGAGCCTGTTGTCAGAGTTGGGAGGGGCTCTGAGCAGTGTTGGGCAGGCCGGGTCTCCCATCCCGAGGCCAGCGTTCCTGTGCAGAGCCCCATCCACTGGTTCTTGCCCTGAGCCACATATGTCTGTGCCATGGGCTGAGTGCCACGACAGGCCCGTGTGACAGCTGCTGCCCACGCATGTGGAAGCTAGGTGGGACTCATTCCTAATTCTGCCGTTGTAATGAGACTTGATTAAAACACCGCCACTTTTTTGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148297-MED22:NM_133640:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.072 A=NA C2=0.438
Domain overlap (PFAM):
C1:
PF061797=Med22=PD(52.1=87.1),PF146811=UPRTase=PD(46.5=75.7)
A:
NA
C2:
PF061797=Med22=PD(52.1=83.6),PF146811=UPRTase=PD(47.0=74.0)
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)