Special

MmuINT0097426 @ mm9

Intron Retention

Gene
ENSMUSG00000015776 | Med22
Description
mediator complex subunit 22 [Source:MGI Symbol;Acc:MGI:98446]
Coordinates
chr2:26760787-26763821:-
Coord C1 exon
chr2:26763613-26763821
Coord A exon
chr2:26761514-26763612
Coord C2 exon
chr2:26760787-26761513
Length
2099 bp
Sequences
Splice sites
5' ss Seq
CAGGTACAA
5' ss Score
7.09
3' ss Seq
GGTTTCTTGTGGTGGCAAAGCTC
3' ss Score
-0.31
Exon sequences
Seq C1 exon
GTTCGAGCTGGTGAGTCACTGATGAAGCTGGTATCCGATCTCAAGCAGTTTCTGATCCTCAACGACTTCCCGTCTGTGAATGAAGCCATCGACCAGCGTAACCAGCAGCTTCGAGCCCTGCAGGAGGAGTGTGACCGCAAGCTCATCACCCTGCGGGACGAGGTCTCCATTGACCTATATGAGCTGGAGGAGGAGTACTACTCGTCCAG
Seq A exon
GTACAAATAGGGCTGGACTGCCATGCAGGTGCTGCCTGCTGCCTGCCCAGACCAGCTAGGGCCTGCAATGGCCTTGTGTTTTTCCAAGTTCTCCTTGGCAGCAGAGCCCCTGACTAGCTCGTTTGACGGACAGACAGTCATAGCCAGCCACCAGCAGGGGCCCAGGCCTTCCCTTCAATGAAGAGGGATGAAAACACAGGACTTGGTTGTGTGTCAACGGCTGTGGCCAGAAAAGGGTATCCCCCAGGGGGCGAGGAAGCCCTCCAGGGCAACACAGTCTCTGTCTTACTGCTTTAAATCTCTTGTCTGTCTAGACAGTTTAGTCAAGGCTGGATTGGCCCCTTGTGGCCTTCCAGGTCTCTAACGACGTTCACTTTCTGGGACAGCCCTGCCTACTGCTTGCTCAGAGATTCAGTTCCATGTGAATGTCATCAGACTCACAGTGGAGAGGTGGGATGGGGGAGGGGTAAGGAACTCAAGCAGGGTGGCTTTGACTCCTGGGCCCAAGATACCTGGATGTCAGCTCGGCCTTATTCATGGAGCTGGAGTCTCCTGGTGTCAGACCTATGTTAGTCTCAGAGGATAGCAGCAGGCAGGATCTGTCACATAGCTCTCTACAGGGCCACTTAGAATGTTGATACCTGAAACTTTCTGATCCAGAGAGGCCTTGAGAAATCAAGAGTCCAGTGTAAAATATGTCGTCGGAACCGGGCTGGAGAATGGAGGCCTTGCCCCACCCCATTAGCTTGAAGTTAAGGTTCCGGTCAGCAGCACCCTGCCTGACTCCCCCTGGTGGTAGGTTTGCTCCTGCTGCTGCTGCACAGAAGCTGCAGTCAACTACAGATGTCCAGTGCTGCAGTGGACATCTTGTTCCCATCTTAGACTCAGTGTCACTGCCAAGCTTCAGTAGTTCTAAAGTTCTCCAGAGAGTTCTGGGGTTATCTTTGGTCTCAGTGTTCATCAGCTTAGCAGAAAAGTGGGAGTATCTACTGTACCCCAAAGTGGCAGAGACTTAGACCAACCCAGGGTGAGTTCCTCACATCTTCCTGTCACTACCTTGTAGTACTTCAAGGACACTTGAGCGGATGAGTACTGGGACAGTGACTCAGTCCTGTACAAGGGTTGAGGGGATAAATTGCTCAGATAGGAACCCAGAGTGCTGGGTTTCCAAAGCCTCGGCCCCTCTGCATCACGTGCATACGTTTCTGGGATGATCTGTGTCCTCTTTGGGCAATCACCTCTCTCATATTCCTCATGGTAAAGCAGCTGCCCCATGCCTAGGAATTTCCTTAAATGGCAGAGTTCTTCGGTAGGTGAGGCAGTAGGTTTTGTCTGCCCCTATCAGCCTCCTGCCCACACCACCACCAGTTGCCCAGCTTCCCCTCTGCATGGCTACTCTTGCCTGTATACGAACTGCTTGCTCTTTCTGGCTTTGCCTTCCCTCCATTCTCCTGGGGATGCTACTCCCTTTGTCTTGGGTAGTTCTGCGAGAGACTGCTGGGGACAGGCATGGGAGAAAGCTAGGGCCTTGTGCATATTAGACAGCTGTAGAAACAGATGTGGTCCAAGTAGCCACTGCTATGACCACTGAGGCATTGTGCTTGCCTCCTCCTGTCTCTGGCTTTCCCTGTGTAATGTAAGGAAATGGAATGTGTAAAGCCTGGGGCTTAGAGCTGTAGAGCTAGAGTAGTGGTATATAGAGAAATGCTCAGACCTGTATTGCTGACTGTTACCCAGTTAGGCCAGGACCCTGTAGGGATGGAAACAGGTCTGCCACCAGGAGCTCTTTGTAAAGTCTCATCACTACCCTACTGGTAAGGGATGGGTAACAGGTAGAGGCTGATAGGAACAAGGAGAGTCCTATGTGTCAAGAAGGACCCATGGGGACAGTTTGCCTAAGTCACATGGCCTGTTGACACCACCTTTCTTTGGATGCAAGAGTGGCCAGAACCGCTTAGCAGAGGGGCCAGCACAGAGGAGAAGAAGGGGAGGCAGTCAGGTGATGTTCATTTCTTAACTCTGCATCTGTCTTGCTTTCCCCTCCCTGGCTTTCCTCTGCCTGCTCCTGTCACTCCTGGGGGTTTCTTGTGGTGGCAAAG
Seq C2 exon
CTCAAGTCTCTGCGAAGCTAATGACCTGCCTCTGTGTGAAGCTTACTGGAGGCTGGACCTCGACGCAGATTCTGCTGATGGCCTCTCAGCCCCTCTTCTGGCGTCCCCGGAGACTGGTGCTGGTCCCTTACAGTCTGCAGCCCCTGTCCACTCCCATGGTGGTGGCCCTGGCCCTACAGAACACACCTGAGCCTCTTGGGGTACCATCGCAGGGTAGCCCTCCCTAGGGCCTAGTTTATCAGAAAGGAAGTGCTGTGGATACCCAGCACAGCCTAGCTTTTTTCAGTTTTAGCTCCCTTGGGGACTTTGGGATCAGGAGCCACTGTAGCCTCAGGAACCTGTCCAGGCCAGGGCCAGTTCCCCGTGATGGTTGGGGAATGCTGTCCAGTTATTTACAGCAGGTGGCTCCCTTCCTGACTGCCAGTGGAAGTTTGTCCCATTGAAGACCTTGAATAGGGAGGGTGGTTGGTGATAGGAAGACAGCCTCAGTTTGTTTAGAATTGTGAGGTATTCAGTGGACCTTAGTCAAGTCCAGTTACCCATCCTTAGGTTCAGGTTCTATAGAGAGCCCTGTCCACTGCCTGCTGCCTGGAGCATAAATGTCTCTGCCACAGCTGACTGTCCAAGATTGTGTGAGAGGCAGCTAGCCAGGGTGTCTTCCTGGATTCTCCCACCATTTCCTTCTGCTACTTTTGAGATGAGACTGTTGAATAAAACATTAGCTTTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000015776-Med22:NM_001033908:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
Alternative protein isoforms





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.078 A=NA C2=0.540
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF061797=Med22=PD(52.1=87.1),PF146811=UPRTase=PD(47.0=77.1)

							
A:
NA

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000015920





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000116442
  



Associated events







Conservation


Human
(hg38)
chr9:133341695-133344124 
ALTERNATIVE
HsaINT0101575
(MED22)
Human
(hg19)
chr9:136208545-136210979 
ALTERNATIVE
HsaINT0101575
(MED22)
Rat
(rn6)
chr3:5454405-5456442 
Cow
(bosTau6)
chr11:104305839-104308265 
ALTERNATIVE
BtaINT0091485
(MED22)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
chr17:7526653-7530588 
ALTERNATIVE
GgaINT0126007
(MED22_CHICK)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"