HsaINT0101770 @ hg38
Intron Retention
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]
Coordinates
chr5:127420044-127422772:+
Coord C1 exon
chr5:127420044-127420207
Coord A exon
chr5:127420208-127422669
Coord C2 exon
chr5:127422670-127422772
Length
2462 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGC
5' ss Score
9.37
3' ss Seq
TGATGCTGTTTTCCATGCAGGAT
3' ss Score
10.64
Exon sequences
Seq C1 exon
GCTGGCACGGGGTGGACTGCTCCATCAGATGTCCCAGTGGCACATGGGGCTTTGGCTGTAACTTAACATGCCAGTGCCTCAACGGGGGAGCCTGCAACACCCTGGACGGGACCTGCACGTGTGCACCTGGATGGCGCGGGGAGAAATGCGAACTTCCCTGCCAG
Seq A exon
GTATGCACAAATCAGCGCCCTGACGGAAAACGCCTATGAGGAACTGATGTTGTAAAGTTGGCTTCTTTTTGCATTTTTCCTGACTTCAAGTGGCTCACTGTGAACCCAACTTCGGTAACTACTGGAAGAATCCAGGTATTTGGATTCAAATTGGACGTAGGATTGGAAAAGAGATAGACATGGAAACTGGTTAGATAGGCTCTGCGAGAATTTCTTCCTTCTTTTCCTTCATCTTGTTCAGTTTCCTCAACCCCCACCCTTTACTTTCTGTTTCTTATTCACCCATCTCTTGGTGGCAGCCAGTGAACAGTACTGGTCTCCAAATATTTTGTTTCCACTATCATGGAAATCTCCCTGCCTTTATGGTAGAAAGTGGCAGGGAGTTGAAAGGAGGGTGGTGACTGATGTCATAGAAATGCTCATGGAAGTGTTGAAAGAAGGTTTGGAAACAATGTCTTTTAACATAAGTATCTCTGGAGCCACAAAAATTTCTTAAGATGTCCCTATAGCTCACTCTATTCCCTTGACCTACTTTGGAGATACAGGTCATTAGAAATCTCATACTGCATCTACCTCAAGCTGTCAGGGAGTGCAAACGGGAAGTGCATTCTGGAGTAAGCTGCTGATTTCTTTTCCATCACTCTTTCTTTCTATAGCAATTATTTTCTCCTGAGCCATTAGGCATTCTCTCTGTGGTGTGTGTTCTCTGCCTCCAGGACATCATCTGATGGCGAGTTAACAATGTGACCCCCTGAACTGGGCCCCTCGAGAAGGGCCTTCCACAATGCTCTTGTCTCTCTGGGCTTCCTCCTCATTAAGTACAACCCACTTCCCAAAATAGAAAGGATCCCACTCATGGATATCCCATGGACAGAGCTGTCAGCTTTGCTGCCTCTCATCACTCTAGTGAACAAATTATCAGTACTTGGAGATGAGCTTGAAGATCACTTTTTACTCCCTATCTGATTGTAGACAAAGCAAAGCCCCTGGCACAATCTCGTCCTTTTTCATACCTTAGAGGAGTTAGTAAATCAGTGAAGGCTGAGGGTTTAGTGGTTCATATCATGACAAAACTAAATCCTGTGTAGCTGTATCAAACATTGGTGGGGTCTACAAAATGATTGTTTTCTTTTTCTTATTTTAACAAGTTCTAGACAAATAATTATTCATCTAGCACCCACTACCTGTCTATGCTGGTTCCCATGTTCCTCCTCTGTGGTAATTCTGTACCCCTGTTTCTCTTAGTTCTTGGGTGGTGTTGGGAAGGCTTGTAGTGCCTCCCTCATTTCCCAGGATCTGTGGTGAAAGAGCTGAACTTTCCATTCTTTCTCCATAAACAAAACAATCATGTCTATGAGGAGTCTTGTCTCCATCAGACCATCCAAACTGACGTGCACATGAAAGTATAAAAGATCTGGAAGGGGAGGAGCAAGGAGGTGTGTCAACTCATACTTAGGACTGTGAGTCAGGATATTTTGTGTGGCTTAGACTTCTTCCTGAAAAGCAGGATAATAATCAGAGAAAAGTAACAAAATATCTTCATTTTTCTTTATAGTACCATGTATCTCGTTGGCAACTTATGGCAATGAACTTAATTCAATTAAAACTATAATTTTTAAGATTAGTTTATAATTTAAAATTTTTTTAAATTATAAATTTTTTTATATTTTATAAAATATAAATAGGCAGGAGAATGGTGTGAACCCGGGAGGCAGAGCTTGCAGTGAGCCGAGATAGCGCCACTGCCGTCCGGCCTGGGTGAAAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAATGACCCTGACCCACACAAAAAAGCTCTAAAATTATAGTTTTAAAACTATAATTTTATAATTTAAAAAATTTTTAAAGTGTGTTGGCATGATTGGCTTCACTATTTATATGTCCCAACCGTTGTGTCAGGCATAAACTAGGGTTTGAGTGACTTTAAAACACTGACTTCCTGGAGCCTATATTTTGGGGACTAAGAAGACATAGAAAGAGGTGATTAAGATGCATCCCTCTGGCTGGGTGCGGTGGCTCACGCCTGTAATCCAAACACTTTGGGAGGCTGAGGCGAGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACAAGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCTGGCAAGGTGGCAGGTGCCTATAGTCCCAGCTACTCGGGAGGCTGAGAATTCCTTCAACCCGGGAGGCCGAGGTTGCGCTGAGCTGAAATCACACCACTGCACTCCAGTCTGGGCAACAGAGCGAGACTCCATCTCAAAAAAAAAGAAAAAAATAAATAAAGATACATCCCTGTAAGAAGCGTTTGGGACAGCAGGGTACTGTATGTGAAATGGCTGACAGTGGCCTTTTCCTCTTCTGTTGTGGGATTTCCCAGGCCCTCATTGCTGCCTTTGATGCTGTTTTCCATGCAG
Seq C2 exon
GATGGCACGTACGGGCTGAACTGTGCTGAGCGCTGCGACTGCAGCCACGCAGATGGCTGCCACCCTACCACGGGCCATTGCCGCTGCCTCCCCGGATGGTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794:ENST00000274473:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF126612=hEGF=PU(69.2=25.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development